Navigation Links
Embryonic Stem Cells Repair Human Heart
Date:8/27/2007

Problems with cell survival, functioning may have been solved in rat experiments

MONDAY, Aug. 27 (HealthDay News) -- Experiments in rats show that human embryonic stem cells can repair damaged heart muscle, improve heart function and slow the progression of heart failure.

Using stem cells to repair damaged hearts is something that appears promising, but so far it has been fraught with problems.

Previous experiments have shown that it is possible to create heart cells from embryonic stem cells. However, most of these cells do not become heart muscle cells, and many don't survive once transplanted into a damaged heart.

"We found a way to increase the survival of these cells," said lead researcher Dr. Charles Murry, director of the Center for Cardiovascular Biology and Regenerative Medicine at the University of Washington, in Seattle.

Murry's team created a "survival" cocktail that prevented the cells from dying. The treated cells were then implanted in rats that had had their hearts damaged to simulate a heart attack.

"If we prepared our cells in this cocktail and transplanted them, we could get virtually 100 percent of the rats to have human heart muscle grafts in them," Murry said.

The researchers compared the rats receiving the cells with three other groups of rats. One group received only injections of water, and another group was given the survival cocktail without cells. The third group was given non-cardiac cells.

The researchers found that the rats that didn't receive the human heart cells all developed heart failure, according to the report in the Aug. 27 online issue of Nature Biotechnology.

"In contrast, the animals that got the human heart muscle grafts implanted in them had a complete reversal of the progression of heart failure," Murry said.

The study shows that growing heart muscle in an injured heart is possible, Murry noted. "In pat
'/>"/>

Copyright©2007 ScoutNews,LLC.
All rights reserved

0

GOOD

Page: 1 2 3

Related medicine news :

1. Embryonic Cells Might Prevent Parkinson’s Disease From Worsenin
2. Embryonic Genetic Testing Is Boosting IVF Pregnancies
3. Sperm stem cells could be an alternative to embryonic stem cells in future
4. T-cells Developed from Human Embryonic Stem Cells
5. Treatment of Spinal Cord Injury with Embryonic Stem Cells
6. Human Embryonic Stem Cells Could Be Later Used In Therapeutic Cloning
7. Researchers Create Genetically-Matched Embryonic Stem Cells for Transplantation
8. Embryonic Selection of Sex can Avoid Conceiving Blind Children
9. Lipid Plays Big Role in Embryonic Development
10. Mice can Produce Embryonic Stem Cells Similar to That of Humans
11. Bush Again Vetoes Embryonic Stem Cell Research Bill

Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/9/2009)...onnector Corporation announces that their design, ... Minneapolis, MN (Vocus) No...the leading manufacturer of miniature high-rel con...nd QA systems have been certified to the ISO 9001:... Quality System Standard., , ,The company,s entire...
(Date:11/9/2009)...thletes are under increasing pressure to play only...sity Health System study of 519 junior tennis play...he risk of injury. Researchers who analyzed 3,366 ... competition found that players who specialized in...rnaments for medical reasons, typically injuries. ...
(Date:11/8/2009)...rengthen Medicare, improve coverage for all Americ.../ -- SUMMARY: Yesterday the United States House ...orm legislation that would strengthen Medicare for...nies that prices millions of Americans out of affo...lth Care for America Act (H.R. 3962) makes prescri...
(Date:11/8/2009)...f the game later, doctors say , , SUNDAY... talk of the NFL this season, sidelining such star...ie Parker. , Officials at the American Podiatri...atric Sports Medicine are warning athletes to take...e football and lacrosse. , "Many fall sports at...
(Date:11/8/2009)...Solutions is pleased to announce that it has been ... for ReSound who recently received an award on the... award includes not only the Veterans Administrati...ederal agencies. , New Yo...ions is pleased to announce that it has been succe...
Breaking Medicine News(10 mins):Health News:Omnetics Connector Corporation Achieves AS9100 Certification 2Health News:Young tennis players who play only 1 sport are more prone to injuries 2Health News:AARP NY Praises House Passage of Health Care Reform Bill 2Health News:AARP NY Praises House Passage of Health Care Reform Bill 3Health News:AARP NY Praises House Passage of Health Care Reform Bill 4Health News:Rx for Fall Foot Injuries 2Health News:3D Global Solutions Selected to Program Manage GN ReSound/VA Digital Hearing Aid Contract 2Health News:3D Global Solutions Selected to Program Manage GN ReSound/VA Digital Hearing Aid Contract 3
...n kid is exhibiting antisocial behaviour, breaking...attention , then the root cause could be the tende...ther than in the morning. The finding is b...s/eveningness', along with the ratio of cortisol r...
...Minogue earned an incredible 4.5million pounds in ... . Despite retreating from the public eye ... doubled her income from the preceding year. ...2.63 million pounds. The 39-year-old was d...
...ways handed over the new five state-of-the-art coa... a train, to Impact India Foundation here today. S... Shri Lalu Prasad said that since 1991, Impact Ind...iors of India where medical facilities are almost ...
...ss Lindsay Lohan's MySpace conversations with alle...aked . Apparently, the 'Mean Girls' star k...h the site and one of them gave Star magazine the ... the 21-year-old says that she wants to marry Rons...
...m the University of Pittsburgh School of Medicine ... an effective treatment for human liver cancer in... Using a newly available monoclonal antibody, ...ccording to the researchers, this finding has sign...
...risk caused by exposure to asbestos has prompted t...bestos . The society has rejected long-held federa...rt of the fire-retarding mineral still being mined... of the Canadian Cancer Society, said. The ...
Other Medicine News:Health News:Late Nights may Make Preteens Antisocial and Aggressive 2Health News:New Lifeline Express Train Inaugurated 2Health News:A New Monoclonal Antibody Kills Cancer Cells 2Health News:Canadian Cancer Society Calls for Ban on Asbestos 2
(Date:11/7/2009)...swire/ -- Most patients with hereditary angioedema...ming HAE attack giving the patients sufficient tim... associated with that attack, according to survey ...ege of Allergy, Asthma & Immunology (ACAAI) An...s fatigue and nausea, which occur frequently befor...
(Date:11/6/2009)...-FirstCall/ -- Oxygen Biotherapeutics, Inc. (OTC B...usly approved reverse split of its common stock wi...Nov. 9, 2009 on a 1-for-15 split-adjusted basis. O...r the new symbol OXBT. The stock also will have a ...mes effective. ,, "This reverse split was overw...
(Date:11/6/2009)...Nov. 6 In consultation with the U....umer Healthcare, Division of McNEIL-PPC, Inc., is ...of product lots of TYLENOL® Arthritis Pain Ca...Z-OPEN CAP. McNeil is initiating the recall after ...ociated with these lots that led to a small number...
Breaking Medicine Technology:Prodromal Symptoms Warn of Hereditary Angioedema Attacks, Give Patients Time to Start Therapy and Decrease Morbidity 2Prodromal Symptoms Warn of Hereditary Angioedema Attacks, Give Patients Time to Start Therapy and Decrease Morbidity 3Oxygen Biotherapeutics, Inc. Announces 1:15 Reverse Stock Split to Take Effect Nov. 9, 2009 2Oxygen Biotherapeutics, Inc. Announces 1:15 Reverse Stock Split to Take Effect Nov. 9, 2009 3McNeil Consumer Healthcare Announces Voluntary Recall of Certain Lots of TYLENOL(R) Arthritis Pain 100 Count with EZ-OPEN CAP 2Los Angeles DUI Attorney Claims Diabetics Often Falsely Convicted of Drunk Driving 57756 1Los Angeles DUI Attorney Claims Diabetics Often Falsely Convicted of Drunk Driving 57756 2Frost 26 Sullivan 3A Key Therapeutic Areas to Remain Strongest Drivers of CRO Revenue Growth in the United States 57752 1Frost 26 Sullivan 3A Key Therapeutic Areas to Remain Strongest Drivers of CRO Revenue Growth in the United States 57752 2Frost 26 Sullivan 3A Key Therapeutic Areas to Remain Strongest Drivers of CRO Revenue Growth in the United States 57752 3Volcano Corporation Announces Schedule of Events for the 2009 Transcatheter Cardiovascular Therapeutics 28TCT 29 Conference 14174 1Volcano Corporation Announces Schedule of Events for the 2009 Transcatheter Cardiovascular Therapeutics 28TCT 29 Conference 14174 2Volcano Corporation Announces Schedule of Events for the 2009 Transcatheter Cardiovascular Therapeutics 28TCT 29 Conference 14174 3Volcano Corporation Announces Schedule of Events for the 2009 Transcatheter Cardiovascular Therapeutics 28TCT 29 Conference 14174 4Volcano Corporation Announces Schedule of Events for the 2009 Transcatheter Cardiovascular Therapeutics 28TCT 29 Conference 14174 5Volcano Corporation Announces Schedule of Events for the 2009 Transcatheter Cardiovascular Therapeutics 28TCT 29 Conference 14174 6
...a national reference laboratory and a worldwide le...ment. ARUP offers an extensive test menu of highly...anatomic pathology. Owned by the University of Uta...lf of the nation's university teaching hospitals a...
...a national reference laboratory and a worldwide le...ment. ARUP offers an extensive test menu of highly...anatomic pathology. Owned by the University of Uta...lf of the nation's university teaching hospitals a...
...a national reference laboratory and a worldwide le...ment. ARUP offers an extensive test menu of highly...anatomic pathology. Owned by the University of Uta...lf of the nation's university teaching hospitals a...
...a national reference laboratory and a worldwide le...ment. ARUP offers an extensive test menu of highly...anatomic pathology. Owned by the University of Uta...lf of the nation's university teaching hospitals a...
Medicine Products: