Navigation Links
Elevated Urate Levels May Slow Parkinson's in Men
Date:4/14/2008

Those with highest amount had almost half the risk of needing to start treatment

MONDAY, April 14 (HealthDay News) -- Men with naturally high levels of the antioxidant urate in their blood appear to develop the symptoms of Parkinson's disease slower than those with lower levels do, a new report says.

The findings, published in the April issue of the Archives of Neurology, support early laboratory studies about urate's protective qualities and offer hope for future disease therapies to delay Parkinson's symptoms such as tremors, rigidity and difficulty walking and talking.

Urate is a salt derived from uric acid, and it is a normal component of blood; however, high levels can lead to gout and kidney stones.

In a two-year study of 800 men recently diagnosed with Parkinson's, researchers from the MassGeneral Institute for Neurodegenerative Disease and Harvard School of Public Health found that those with the highest urate levels at the study's start had almost half the risk of needing to start Parkinson's treatment drugs as did those with the lowest levels.

Brain scans showed that participants with higher urate levels also lost the fewest dopamine-producing neurons. Parkinson's disease is caused when brain cells that produce the neurotransmitter dopamine are destroyed.

"These findings, combined with prior knowledge of urate's protective properties in laboratory studies, raise the possibility that urate-elevating strategies could be used to slow the neurodegeneration of Parkinson's disease," study author Michael Schwarzschild, an associate professor of neurology at Harvard Medical School, said in a prepared statement.

"Potential benefits of urate have to be tempered against the known risks of elevated urate levels, which include gout and kidney stones. From what we know now, urate elevation should only be attempted in the context of a closely monitored clinical trial, in which potential benefits and risks are carefully balanced," Schwarzschild said.

More information

We Move has more about Parkinson's disease.



-- Kevin McKeever



SOURCE: Harvard School of Public Health/Massachusetts General Hospital, news release, April 14, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Impact of elevated homocysteine levels on vision under study
2. Ranexa(R) Significantly Reduces Incidence of CV Death, MI or Recurrent Ischemia in MERLIN TIMI-36 Patients With Elevated BNP
3. Store-bought freshwater fish contain elevated levels of mercury, arsenic and selenium
4. CRESTOR(R) Now Indicated to Slow the Progression of Atherosclerosis in Patients With Elevated Cholesterol
5. Elevated liver enzymes associated with higher future mortality
6. Envisat makes first ever observation of regionally elevated CO2 from manmade emissions
7. Saturated Fat: Even a Little Splurge May Be Too Much
8. Molecular profiling can accurately predict survival in colon cancer patients
9. PET scans can accurately detect a breast tumors response to chemotherapy
10. ADA Calls for Scientifically Accurate Patient Brochure Explaining Filling Choices
11. Dr. Laura Jana Offers Parents Five Key Ways to Ensure Accurate Dosing of Liquid Medication to Infants
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Elevated Urate Levels May Slow Parkinson's  in Men
(Date:2/7/2016)... Orion, Clarkston, Metamora, Michigan (PRWEB) , ... February ... ... to correct pelvic organ prolapse with the latest techniques and the most minimally ... risk for pelvic organ prolapse, particularly after menopause. Other risk factors include surgery ...
(Date:2/7/2016)... ... February 07, 2016 , ... ... MyDecision™ empowers employers and organizations with the tools and information to lower the ... elements to cut the cost of providing employee healthcare benefits by as much ...
(Date:2/6/2016)... ... February 06, 2016 , ... FOR ... AT AORN SURGICAL CONFERENCE & EXPO , WHAT:     , This conference is ... 5000 perioperative nurses in attendance to study the latest evidence-based recommendations and ...
(Date:2/6/2016)... ... February 06, 2016 , ... With the FCPX LUT: Summer ... to their footage. A LUT is a Lookup Table that contains a mathematical formula ... indicated by the table. By manipulating each pixel, LUT's can change each color range ...
(Date:2/6/2016)... ... 06, 2016 , ... Research has shown that building shame ... frequency and level of relapse. , At the 2016 iaedp Symposium, ... explore the critical tasks of the recovery phase and beyond including relapse prevention ...
Breaking Medicine News(10 mins):
(Date:2/8/2016)... NORRITON, Pa. , Feb. 8, 2016 /PRNewswire/ ... of November Research Group (NRG),s pharmacovigilance technology ... pharmacovigilance system-related consulting services and an Oracle Argus ... compliance services to Life Sciences companies. ... strengthens and expands HighPoint,s life sciences capabilities and ...
(Date:2/8/2016)... , Switzerland and PALO ALTO, Calif. , ... biological and chemical manufacturing, and Kodiak Sciences Inc., a ... treatment of retinal disease, announced today agreements for the ... Lonza will manufacture material at multiple sites, including Slough ... --> --> Retinal diseases, such ...
(Date:2/8/2016)... , Feb. 8, 2016  Avista Pharma Solutions ("Avista ... Setzer as Chief Financial Officer (CFO). Mr. Setzer is ... of experience in various roles within growing technology and ... served as the Executive Director of Finance at INC ... Raleigh, NC . Previously, Mr. Setzer served ...
Breaking Medicine Technology: