Navigation Links
Elevated Urate Levels May Slow Parkinson's in Men
Date:4/14/2008

Those with highest amount had almost half the risk of needing to start treatment

MONDAY, April 14 (HealthDay News) -- Men with naturally high levels of the antioxidant urate in their blood appear to develop the symptoms of Parkinson's disease slower than those with lower levels do, a new report says.

The findings, published in the April issue of the Archives of Neurology, support early laboratory studies about urate's protective qualities and offer hope for future disease therapies to delay Parkinson's symptoms such as tremors, rigidity and difficulty walking and talking.

Urate is a salt derived from uric acid, and it is a normal component of blood; however, high levels can lead to gout and kidney stones.

In a two-year study of 800 men recently diagnosed with Parkinson's, researchers from the MassGeneral Institute for Neurodegenerative Disease and Harvard School of Public Health found that those with the highest urate levels at the study's start had almost half the risk of needing to start Parkinson's treatment drugs as did those with the lowest levels.

Brain scans showed that participants with higher urate levels also lost the fewest dopamine-producing neurons. Parkinson's disease is caused when brain cells that produce the neurotransmitter dopamine are destroyed.

"These findings, combined with prior knowledge of urate's protective properties in laboratory studies, raise the possibility that urate-elevating strategies could be used to slow the neurodegeneration of Parkinson's disease," study author Michael Schwarzschild, an associate professor of neurology at Harvard Medical School, said in a prepared statement.

"Potential benefits of urate have to be tempered against the known risks of elevated urate levels, which include gout and kidney stones. From what we know now, urate elevation should only be attempted in the context of a closely monitored clinical trial, in which potential benefits and risks are carefully balanced," Schwarzschild said.

More information

We Move has more about Parkinson's disease.



-- Kevin McKeever



SOURCE: Harvard School of Public Health/Massachusetts General Hospital, news release, April 14, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Impact of elevated homocysteine levels on vision under study
2. Ranexa(R) Significantly Reduces Incidence of CV Death, MI or Recurrent Ischemia in MERLIN TIMI-36 Patients With Elevated BNP
3. Store-bought freshwater fish contain elevated levels of mercury, arsenic and selenium
4. CRESTOR(R) Now Indicated to Slow the Progression of Atherosclerosis in Patients With Elevated Cholesterol
5. Elevated liver enzymes associated with higher future mortality
6. Envisat makes first ever observation of regionally elevated CO2 from manmade emissions
7. Saturated Fat: Even a Little Splurge May Be Too Much
8. Molecular profiling can accurately predict survival in colon cancer patients
9. PET scans can accurately detect a breast tumors response to chemotherapy
10. ADA Calls for Scientifically Accurate Patient Brochure Explaining Filling Choices
11. Dr. Laura Jana Offers Parents Five Key Ways to Ensure Accurate Dosing of Liquid Medication to Infants
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Elevated Urate Levels May Slow Parkinson's  in Men
(Date:10/13/2017)... ... October 13, 2017 , ... ProVest Insurance ... greater Dallas, Miami, and Raleigh regions, is organizing an extended charity drive to ... and deadly chromosome abnormality. , After struggling since birth with several health challenges, ...
(Date:10/13/2017)... Ky. (PRWEB) , ... October 13, 2017 , ... The ... MPH to become its next President and Chief Executive Officer, succeeding Dr. James C. ... CEO Elect beginning July 1, 2018 until Dr. Puffer’s retirement at the end of ...
(Date:10/13/2017)... ... October 13, 2017 , ... Lori R. Somekh, founder of ... ElderCounsel, a national organization of elder law and special needs planning attorneys. “Membership in ... It also provides a forum to network with elder law attorneys nationwide,” said Somekh. ...
(Date:10/13/2017)... ... 13, 2017 , ... Ellevate Network, the leading network for professional women, brought ... gender equality at their inaugural Summit in New York City in June. The event ... audience of over 3 million. To watch the Mobilize Women video, click here ...
(Date:10/13/2017)... VA (PRWEB) , ... October 13, 2017 , ... ... of DevOps and Agile Software Development, has been awarded a contract by the ... Blanket Purchase Agreement (BPA) aims to accelerate the enterprise use of Agile methodologies ...
Breaking Medicine News(10 mins):
(Date:10/12/2017)... 12, 2017 AVACEN Medical , Inc. (AVACEN) ... their  2017 New Product Innovation Award for Its fibromyalgia ... and secondary medical device market research by Frost & Sullivan,s ... OTC, drug-free pain relief product, the AVACEN 100, offers a ... fibromyalgia widespread pain. ...
(Date:10/11/2017)... 2017  True Health, a leader in integrated ... during National Breast Cancer Awareness month to educate ... Research recently published ... more than 10 million American women are at ... or BRCA2 and have not had testing. These mutations ...
(Date:10/5/2017)...  In response to the nationwide opioid epidemic, ... (AAOMS) released prescribing recommendations that urge ibuprofen – ... a first-line therapy to manage a patient,s acute ... Recognizing the value and importance of the ... Acute and Postoperative Pain Management" stresses that practitioners ...
Breaking Medicine Technology: