Navigation Links
Elevated Urate Levels May Slow Parkinson's in Men
Date:4/14/2008

Those with highest amount had almost half the risk of needing to start treatment

MONDAY, April 14 (HealthDay News) -- Men with naturally high levels of the antioxidant urate in their blood appear to develop the symptoms of Parkinson's disease slower than those with lower levels do, a new report says.

The findings, published in the April issue of the Archives of Neurology, support early laboratory studies about urate's protective qualities and offer hope for future disease therapies to delay Parkinson's symptoms such as tremors, rigidity and difficulty walking and talking.

Urate is a salt derived from uric acid, and it is a normal component of blood; however, high levels can lead to gout and kidney stones.

In a two-year study of 800 men recently diagnosed with Parkinson's, researchers from the MassGeneral Institute for Neurodegenerative Disease and Harvard School of Public Health found that those with the highest urate levels at the study's start had almost half the risk of needing to start Parkinson's treatment drugs as did those with the lowest levels.

Brain scans showed that participants with higher urate levels also lost the fewest dopamine-producing neurons. Parkinson's disease is caused when brain cells that produce the neurotransmitter dopamine are destroyed.

"These findings, combined with prior knowledge of urate's protective properties in laboratory studies, raise the possibility that urate-elevating strategies could be used to slow the neurodegeneration of Parkinson's disease," study author Michael Schwarzschild, an associate professor of neurology at Harvard Medical School, said in a prepared statement.

"Potential benefits of urate have to be tempered against the known risks of elevated urate levels, which include gout and kidney stones. From what we know now, urate elevation should only be attempted in the context of a closely monitored clinical trial, in which potential benefits and risks are carefully balanced," Schwarzschild said.

More information

We Move has more about Parkinson's disease.



-- Kevin McKeever



SOURCE: Harvard School of Public Health/Massachusetts General Hospital, news release, April 14, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Impact of elevated homocysteine levels on vision under study
2. Ranexa(R) Significantly Reduces Incidence of CV Death, MI or Recurrent Ischemia in MERLIN TIMI-36 Patients With Elevated BNP
3. Store-bought freshwater fish contain elevated levels of mercury, arsenic and selenium
4. CRESTOR(R) Now Indicated to Slow the Progression of Atherosclerosis in Patients With Elevated Cholesterol
5. Elevated liver enzymes associated with higher future mortality
6. Envisat makes first ever observation of regionally elevated CO2 from manmade emissions
7. Saturated Fat: Even a Little Splurge May Be Too Much
8. Molecular profiling can accurately predict survival in colon cancer patients
9. PET scans can accurately detect a breast tumors response to chemotherapy
10. ADA Calls for Scientifically Accurate Patient Brochure Explaining Filling Choices
11. Dr. Laura Jana Offers Parents Five Key Ways to Ensure Accurate Dosing of Liquid Medication to Infants
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Elevated Urate Levels May Slow Parkinson's  in Men
(Date:6/25/2016)... , ... June 25, 2016 , ... The temporary closing of Bruton Memorial Library on ... Observer , brings up a new, often overlooked aspect of head lice: the parasite’s ability ... fumigation is not a common occurrence, but a necessary one in the event that lice ...
(Date:6/25/2016)... Oklahoma City, Oklahoma (PRWEB) , ... June 25, ... ... to helping both athletes and non-athletes recover from injury. Recently, he has implemented ... for the Oklahoma City area —Johnson is one of the first doctors to ...
(Date:6/24/2016)... Marne, Michigan (PRWEB) , ... June 24, 2016 , ... ... To deal with these feelings, many turn to unhealthy avenues, such as drug or ... Center of Marne, Michigan, has released tools for healthy coping following a traumatic event. ...
(Date:6/24/2016)... ... 24, 2016 , ... Global law firm Greenberg Traurig, P.A. announced that 20 ... by their peers for this recognition are considered among the top 2 percent of ... honors as members of this year’s Legal Elite Hall of Fame: Miami Shareholders ...
(Date:6/24/2016)... ... June 24, 2016 , ... People across the U.S. are ... Code Talker Award, an essay contest in which patients and their families pay tribute ... presented at the 2016 National Society of Genetic Counselors (NSGC) Annual Education Conference (AEC) ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... Belgium , June 24, 2016 /PRNewswire/ ... announced the appointment of Dr. Edward Futcher ... a Non-Executive Director, effective June 23, 2016.Dr. Futcher ... and Nominations and Governance Committees.  As a non-executive ... provide independent expertise and strategic counsel to VolitionRx ...
(Date:6/23/2016)... DUBLIN , June 23, 2016 ... the "Pharmaceutical Excipients Market by Type (Organic Chemical ... Preservative), Formulation (Oral, Topical, Coating, Parenteral) - Global Forecast ... The global pharmaceutical excipients ... 2021 at a CAGR of 6.1% in the forecast ...
(Date:6/23/2016)... -- Research and Markets has announced the addition ... to their offering. The ... commercial environment for MedImmune to enter. The US ageing population ... to drive considerable growth for effective anti-influenza medications. The introduction ... considerably, but development is still in its infancy. ...
Breaking Medicine Technology: