Navigation Links
Elevated Antibody Levels May Predict Rheumatoid Arthritis Risk
Date:9/7/2012

FRIDAY, Sept. 7 (HealthDay News) -- Elevated blood levels of an antibody called rheumatoid factor are associated with an increased long-term risk of rheumatoid arthritis, a new study contends.

Women in their 50s and 60s who smoke appear to have the highest risk, according to the Danish researchers.

The researchers measured rheumatoid factor levels in more than 9,700 people, aged 20 to 100, who did not have rheumatoid arthritis at the start of the study. The participants were followed for up to 28 years. During that time, 183 people developed rheumatoid arthritis.

People with a rheumatoid factor level twice the normal level (less than 25 international units per milliliter) had a 3.3-fold increased risk of developing rheumatoid arthritis. Those with the highest rheumatoid factor levels (100 IU/mL or more) had a 26-fold increased risk.

The highest 10-year risk of rheumatoid arthritis (32 percent) was found in women aged 50 to 69 who smoked and had rheumatoid factor at the highest levels. The lowest 10-year risk (0.1 percent) was found in men 70 and older with rheumatoid factor at normal levels.

The findings do not prove that rheumatoid factor is a cause of rheumatoid arthritis, but do suggest that people with a positive rheumatoid factor test should be referred to a rheumatologist for examination, the researchers said.

The study was published online Sept. 6 in the British Medical Journal.

Rheumatoid arthritis is a chronic inflammatory joint disorder that affects about 1 percent of people worldwide, according to the American College of Rheumatology. Women are three times more likely to develop the condition than men.

More information

The American Academy of Family Physicians has more about rheumatoid arthritis.

-- Robert Preidt

SOURCE: British Medical Journal, news release, Sept. 6, 2012


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Study confirms early elevated HIV infection risk in some Step Study participants
2. Nerve growth factors elevated in pancreatic cancer model
3. Male Ontario students show declines in fighting; females show elevated bullying and mental distress
4. Children exposed to 2 phthalates have elevated risk of asthma-related airway inflammation
5. Antibody therapy prevents gastrointestinal damage following radiation exposure in mice
6. Scientists Pinpoint Antibody That May Be Specific to MS Patients
7. NIH scientists map first steps in flu antibody development
8. Normal triglyceride levels in people of African descent may hinder diagnosis of metabolic syndrome
9. Heart failure patients with diabetes may benefit from higher glucose levels
10. Cholesterol Levels Vary Widely by Country: Study
11. Low oxygen levels could drive cancer growth
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Elevated Antibody Levels May Predict Rheumatoid Arthritis Risk
(Date:6/27/2016)... ... June 27, 2016 , ... TherapySites, the ... affiliation with Tennessee Counseling Association. This new relationship allows TherapySites to ... Counseling Association, adding exclusive benefits and promotional offers. , "TCA is extremely excited ...
(Date:6/26/2016)... ... ... Quality metrics are proliferating in cancer care, and are derived from many ... the beholder, according to experts who offered insights and commentary in the current issue ... the full issue, click here . , For the American Society of Clinical ...
(Date:6/26/2016)... ... ... blind and certified personal trainer is helping to develop a weight loss fitness plan that ... the two major problems leading the fitness industry today:, , All ... They don’t eliminate all the reasons people quit their exercise program , ...
(Date:6/25/2016)... ... , ... The temporary closing of Bruton Memorial Library on June 21 due to a possible ... often overlooked aspect of head lice: the parasite’s ability to live away from a human ... but a necessary one in the event that lice have simply gotten out of control. ...
(Date:6/25/2016)... ... June 25, 2016 , ... Dr. ... from injury. Recently, he has implemented orthobiologic procedures as a method for treating ... one of the first doctors to perform the treatment. Orthobiologics are substances that ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... HILL, N.C. , June 24, 2016 /PRNewswire/ ... healthcare decisions and regulators/payers have placed more emphasis ... new environment, patient support programs in the pharmaceutical ... for patients, medications. Consequently, pharmaceutical companies are focusing ... ensure they are providing products and services that ...
(Date:6/24/2016)... FRANCISCO, Calif. , June 24, 2016 /PRNewswire/ ... ), a biopharmaceutical company developing novel therapeutics for ... unmet needs, today announced the closing of its ... of common stock, at the public offering price ... in the offering were offered by GBT. GBT ...
(Date:6/24/2016)... , June 24, 2016 ... Markets has announced the addition of the " ... offering. This ... and provides an updated review, including its applications in ... the total market, which includes three main industries: pharmaceutical ...
Breaking Medicine Technology: