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Elderly patients in need of heart valve replacements have alternative to surgery
Date:6/15/2010

Doctors at the University Heart Center in Hamburg, Germany successfully used transcatheter valve-in-valve implantation in elderly patients with degenerated bioprostheses in aortic and mitral position. This minimally invasive procedure was used as an alternative treatment option for patients who were at high surgical risk. Full details of the study are available in the June issue of Catheterization and Cardiovascular Interventions, a journal published by Wiley-Blackwell on behalf of The Society for Cardiovascular Angiography and Interventions.

Recently, heart valve replacement surgery made headlines after broadcast journalist, Barbara Walters, underwent the procedure last month. Each year more than 300,000 patients worldwide have this surgery to repair problematic or diseased heart valves. The replacement valves can be mechanical, of which modern versions can last indefinitely, or tissue (xenograft) valves that on average last 15 years. With mechanical valves, patients must also be treated with anticoagulant drugs. However, reoperation which is the standard treatment to replace degenerated valves, is not always an option for patients who are at greater morbidity risk due to advanced age and other compounding issues such as renal dysfunction.

In the current study, Moritz Seiffert, M.D., and colleagues report on their experience with transcatheter valve-in-valve implantation in 5 patients with significant xenograft degeneration of 15.4 years after aortic (n=4) and mitral (n=1) valve replacement. The mean age of patients was 82 years and predicted operative mortality was 55.8% based on the European System for Cardiac Operative Risk Evaluation (EuroSCORE). Successful transcatheter valve-in-valve implantation was performed in all patients through a transapical access with a 23-mm Edwards Sapien valve deployed into the degenerated valve.

Post-procedure results show the mean trans-valvular gradients were reduced from 31.2
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Contact: Dawn Peters
Healthnews@wiley.com
781-388-8408
Wiley-Blackwell
Source:Eurekalert

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