Navigation Links
Elderly patients in need of heart valve replacements have alternative to surgery
Date:6/15/2010

Doctors at the University Heart Center in Hamburg, Germany successfully used transcatheter valve-in-valve implantation in elderly patients with degenerated bioprostheses in aortic and mitral position. This minimally invasive procedure was used as an alternative treatment option for patients who were at high surgical risk. Full details of the study are available in the June issue of Catheterization and Cardiovascular Interventions, a journal published by Wiley-Blackwell on behalf of The Society for Cardiovascular Angiography and Interventions.

Recently, heart valve replacement surgery made headlines after broadcast journalist, Barbara Walters, underwent the procedure last month. Each year more than 300,000 patients worldwide have this surgery to repair problematic or diseased heart valves. The replacement valves can be mechanical, of which modern versions can last indefinitely, or tissue (xenograft) valves that on average last 15 years. With mechanical valves, patients must also be treated with anticoagulant drugs. However, reoperation which is the standard treatment to replace degenerated valves, is not always an option for patients who are at greater morbidity risk due to advanced age and other compounding issues such as renal dysfunction.

In the current study, Moritz Seiffert, M.D., and colleagues report on their experience with transcatheter valve-in-valve implantation in 5 patients with significant xenograft degeneration of 15.4 years after aortic (n=4) and mitral (n=1) valve replacement. The mean age of patients was 82 years and predicted operative mortality was 55.8% based on the European System for Cardiac Operative Risk Evaluation (EuroSCORE). Successful transcatheter valve-in-valve implantation was performed in all patients through a transapical access with a 23-mm Edwards Sapien valve deployed into the degenerated valve.

Post-procedure results show the mean trans-valvular gradients were reduced from 31.2 to 19.0 mm Hg in the aortic location and 9 to 3 mm Hg in the mitral position. Doctors did not report any significant regurgitation (backwards blood flow). Two high-risk patients expired within 30 days due to low cardiac output and acute hemorrhage, respectively. One of the deaths occurred in a patient who presented with a EuroSCORE of 88.9%.

"Transcatheter valve-in-valve implantation offers an alternative treatment option for elderly patients who have disproportional operative risks," said Dr. Seiffert. The doctors highlight that reoperative valve surgery was not an option in these candidates and valve-in-valve implantation turned out to be a valuable bail-out procedure.

"As the aged population continues to grow, a minimally-invasive procedure such as transcatheter valve-in-valve implantation is a promising alternative," concluded Dr. Seiffert. "However adequate patient selection and an interdisciplinary approach are crucial to the success of this procedure."


'/>"/>

Contact: Dawn Peters
Healthnews@wiley.com
781-388-8408
Wiley-Blackwell
Source:Eurekalert

Related medicine news :

1. Elderly drivers ability to detect hazards doesnt degrade with age according to Ben-Gurion U.
2. Eyeglass Change Might Keep Elderly From Falling
3. Elderly Falls Linked to Altered Blood Flow in Brain
4. Kidney Removal May Be Ill-Advised for Some Elderly
5. Kidney removal does not prolong the lives of elderly patients with localized kidney cancer
6. 1 in 4 Chronically Ill Elderly Lives Alone
7. More than one-quarter of elderly patients lack decision-making capacity at death
8. More Family Support Can Raise Fears For Some Elderly
9. Knee replacement in elderly patients shown to improve balance
10. Death After Discharge Rates Higher in Elderly ICU Patients
11. Young Men and Elderly Women at Biggest Risk for Shoulder Dislocations
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/27/2016)... Viejo, California (PRWEB) , ... June 27, 2016 , ... ... are fully customizable inside of Final Cut Pro X," said Christina Austin - CEO ... another unique style. Final Cut Pro X users can now reveal the ...
(Date:6/27/2016)... ... June 27, 2016 , ... ... strategic partnership with Connance, a healthcare industry leader providing predictive analytics to ... technology combine to provide health systems, hospitals and ambulatory surgical centers with ...
(Date:6/27/2016)... Overland Park, KS (PRWEB) , ... June 27, 2016 , ... ... leader in retailers of Eyeglasses . , Millions of individuals in the United ... life, eyeglasses have become a way to both correct vision and make a fashion ...
(Date:6/26/2016)... ... 26, 2016 , ... On June 10-11, 2016, A Forever Recovery, a holistic ... World’s Longest Breakfast Table in Battle Creek, MI, where the rehabilitation facility is located. ... some of the world’s leading providers of cereal and other breakfast foods. Its residents ...
(Date:6/26/2016)... ... June 26, 2016 , ... PawPaws brand pet supplements ... that was developed to enhance the health of felines. The formula is all-natural and ... main herbs in the PawPaws Cat Kidney Support Supplement Soft Chews are ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... -- Jazz Pharmaceuticals plc (Nasdaq: JAZZ ) ... Improvements Act of 1976, as amended ("HSR"), with respect ... Nasdaq: CPXX ) expired effective June 24, ... As previously announced on May 31, 2016, Jazz Pharmaceuticals ... which Jazz Pharmaceuticals has commenced a tender offer for ...
(Date:6/24/2016)... HILL, N.C. , June 24, 2016 /PRNewswire/ ... healthcare decisions and regulators/payers have placed more emphasis ... new environment, patient support programs in the pharmaceutical ... for patients, medications. Consequently, pharmaceutical companies are focusing ... ensure they are providing products and services that ...
(Date:6/24/2016)... CAMBRIDGE, Mass. , June 24, 2016 /PRNewswire/ ... the Spaulding Rehabilitation Network,s Dean Center for ... of Physical Medicine and Rehabilitation, MIT Hacking Medicine, ... Center for Innovation, today announced the five finalists ... Hackathon for Lyme disease.  More than 100 scientists, ...
Breaking Medicine Technology: