Navigation Links
Elderly Dutch lung patients' survival improved by new treatment options between 2003-2009
Date:7/6/2011

New developments such as stereotactic ablative radiotherapy and improvements in surgical care in early-stage lung cancer have led to large survival gains for elderly Dutch patients, according to a population-based study presented at the 14th World Conference on Lung Cancer in Amsterdam, hosted by the International Association for the Study of Lung Cancer (IASLC).

The median survival for Dutch non-small cell lung cancer (NSCLC) patients increased by nearly 8 months between 2003 and 2009, following the advent of stereotactic ablative radiotherapy.

"In fit patients, surgery is accepted as the standard of care in an early-stage lung cancer, with radiation therapy widely considered a second choice," said Dr. Suresh Senan of VU University Medical Center in Amsterdam, one of the investigators.

However, only about one in every three patients aged 75 years and older is fit to undergo surgery. Until about 2003, up to 40 percent of elderly Dutch patients were left untreated because the second choice, conventional radiation -- which takes approximately 6-7 weeks to deliver and is associated with high recurrence rates -- was considered unattractive, Dr. Senan said.

Stereotactic ablative radiotherapy (SABR) was introduced in the Netherlands in 2003 and rapidly became the standard of care for peripheral stage I lung tumors measuring up to about 6 cm. SABR is a form of high-precision radiotherapy, characterized by the use of very high biological doses of radiation delivered in between 3 and 8 fractions in a 2-3 week period as an outpatient procedure.

Using data from the Netherlands Cancer Registry (NCR), researchers determined that the median survival of all elderly Dutch NSCLC patients increased to 24.4 months from 16.4 months between 2001 and 2009.

Radiotherapy utilization increased to 37.7% from 31.2%, and the corresponding median survival for patients treated with radiation increased by nearly 10 months, to 26.1 months from 16.8 months. No significant change in survival was seen in the group of patients that received no treatment.

"Patients who are aged 75 years and older, and who are fit to undergo surgery, should also be informed about a second curative modality of SABR, and about the differences in mortality and complications between these two treatments," Dr. Senan said. "Participation in the ongoing prospective clinical trials comparing surgery and SABR in fitter patient populations should be strongly encouraged."


'/>"/>

Contact: Renee McGaw
renee.mcgaw@ucdenver.edu
31-205-493-413
International Association for the Study of Lung Cancer
Source:Eurekalert

Related medicine news :

1. Alcohol drinking in the elderly: Risks and benefits
2. Not all hospitals treat elderly the same
3. Study shows elderly drivers support competency tests
4. CPAP decreases cardiovascular mortality in elderly patients
5. Families need to know more about feeding tubes for elderly dementia patients
6. Socializing May Keep Elderly Minds Sharp
7. Thyroid Drugs May Raise Fracture Risk in Elderly
8. Being Housebound Linked to Alzheimers in Elderly
9. Experts Offer New Guidance for Blood Pressure Control in Elderly
10. Chronic Kidney Disease Tied to Heart Problems in Elderly
11. Researchers find many elderly men are undergoing unnecessary PSA screenings
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/18/2017)... ... January 18, 2017 , ... During ... disease to enamel erosion, and those dental problems can increase the risk of ... many pregnant women are failing to get the dental care they need. Agoura ...
(Date:1/17/2017)... ... January 17, 2017 , ... In the ... Activewear is a stand-out company for several differences from other mainstream brands. ... on demand, this is called 'Agile' manufacturing - http://www.leanproduction.com/agile-manufacturing.html . It allows ...
(Date:1/17/2017)... Florida (PRWEB) , ... January 17, 2017 , ... Kevin ... Producers of AsSeenOnTV.pro will be featuring DRTV campaigns regarding the topic of Beauty and ... become a better version of themselves. What better way to commit to these changes ...
(Date:1/17/2017)... ... January 17, 2017 , ... ... continuing education for EMS and firefighting professionals, has released four new continuing education ... new courses are taught live in an online classroom and meet the requirements ...
(Date:1/17/2017)... ... ... Neil H. Greco Insurance Agency, a northern New Jersey firm that provides ... a charity drive to raise awareness of heart disease and promote habits that improve ... is responsible for 1 in every 4 deaths at the national level each year. ...
Breaking Medicine News(10 mins):
(Date:1/18/2017)... SHANGHAI , Jan. 18, 2017 In ... of revolution, which is where the Upgrade of ... year of the 13th Five-Year Plan for Economic and Social ... (the 13th Five-Year Plan), and the state council of ... the "13th Five-Year" national strategic emerging industry development plan, identifying ...
(Date:1/18/2017)... Invetech, the leading developer of ... , has announced a collaboration agreement with Erytech ... treatments for acute leukemia and other oncology indications ... will develop systems to enable the commercial-scale manufacture ... platform, which uses a novel technology to encapsulate ...
(Date:1/18/2017)... , Jan. 18, 2017  Tarix Orphan LLC today ... granted a Rare Pediatric Disease (RPD) designation for the ... Dystrophic Epidermolysis Bullosa (RDEB), a rare genetic skin disorder. ... treatment is limited to supportive care. "The ... Drug Designation previously granted by the FDA in this ...
Breaking Medicine Technology: