Navigation Links
Einstein scientists propose new theory of autism
Date:4/1/2009

y brain system involved both in producing fever and controlling behavior," says co-author Dominick P. Purpura, M.D., dean emeritus and distinguished professor of neuroscience at Einstein.

The locus coeruleus has widespread connections to brain regions that process sensory information. It secretes most of the brain's noradrenaline, a neurotransmitter that plays a key role in arousal mechanisms, such as the "fight or flight" response. It is also involved in a variety of complex behaviors, such as attentional focusing (the ability to concentrate attention on environmental cues relevant to the task in hand, or to switch attention from one task to another). Poor attentional focusing is a defining characteristic of autism.

"What is unique about the locus coeruleus is that it activates almost all higher-order brain centers that are involved in complex cognitive tasks," says Dr. Mehler.

Drs. Purpura and Mehler hypothesize that in autism, the LC-NA system is dysregulated by the interplay of environment, genetic, and epigenetic factors (chemical substances both within as well as outside the genome that regulate the expression of genes). They believe that stress plays a central role in dysregulation of the LC-NA system, especially in the latter stages of prenatal development when the fetal brain is particularly vulnerable.

As evidence, the researchers point to a 2008 study, published in the Journal of Autism and Developmental Disorders, that found a higher incidence of autism among children whose mothers had been exposed to hurricanes and tropical storms during pregnancy. Maternal exposure to severe storms at mid-gestation resulted in the highest prevalence of autism.

Drs. Purpura and Mehler believe that, in autistic children, fever stimulates the LC-NA system, temporarily restoring its normal regulatory function. "This could not happen if autism was caused by a lesion or some structural abnormality of the brain," says Dr. Pur
'/>"/>

Contact: Deirdre Branley
dbranley@aecom.yu.edu
718-430-2923
Albert Einstein College of Medicine
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Einstein researchers discover protein that contributes to cancer spread
2. Lt. Col. Weinstein, New Book: Universal Health Care Will Not Work Unless
3. Senator Dianne Feinstein Denounces Prop 8
4. Feinstein Institute: Researching a Family Tree of Autoimmune Disorders
5. Chemical liberated by leaky gut may allow HIV to infect the brain, Einstein scientists find
6. Senators Chuck Hagel and Dianne Feinstein Make Lung Cancer Matter
7. NIH awards Einstein College of Medicine & Montefiore Medical Center $22M grant
8. Einstein-Montefiore Center for AIDS Research receives $8.5M award from NIH
9. The Feinstein to collaborate with Swedens Karolinska Institute
10. Pioneering Heart Surgeon, Robert E. Michler, M.D., Appointed Chair of Surgery and Surgeon-in-Chief at Einstein and at Montefiore Medical Center
11. Novel discovery by Einstein scientists could lead to much-needed kidney failure treatment
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/14/2014)... Texas (PRWEB) July 14, 2014 The ... encourage investment in the Global Mobile Health Solutions market. ... in the Health IT for Economic and Clinical Health ... February 2009. , Analysts forecast the Global Mobile ... of 34.88 percent over the period 2013-2018. According to ...
(Date:7/14/2014)... The report “Intelligent Building Automation Technologies ... Safety, Facility Management], IT Technologies & Industry Verticals ... - 2019)” defines and segments the IBAS market ... forecasting of revenues. The report also identifies the ... impacting it, along with the technology roadmap and ...
(Date:7/14/2014)... Physical fitness may buffer some of the adverse health ... study by researchers from the American Cancer Society, The ... appears in the journal Mayo Clinic Proceeding s, ... obesity and blood markers associated with cardiovascular disease is ... Sedentary behavior has been linked to an increase risk ...
(Date:7/14/2014)... TX (PRWEB) July 14, 2014 ... heart valves market in Americas. The analysis includes ... the 2007–2020 period and key company share data ... US, Canada, Brazil and Mexico. It uses data ... secondary research and in-house analysis. , Scope, ...
(Date:7/14/2014)... Secure Decisions, a leading provider of ... the Software Assurance Marketplace (SWAMP) to build a powerful ... drives everyday life. , The SWAMP, implemented by a ... Morgridge Institute for Research, is funded by the Department ... practices by building a free facility with a diverse ...
Breaking Medicine News(10 mins):Health News:Mobile Health Solutions Market to Grow at 34.88% CAGR by 2018, Says a New Research Report at Sandlerresearch.org 2Health News:Mobile Health Solutions Market to Grow at 34.88% CAGR by 2018, Says a New Research Report at Sandlerresearch.org 3Health News:Mobile Health Solutions Market to Grow at 34.88% CAGR by 2018, Says a New Research Report at Sandlerresearch.org 4Health News:Intelligent Building Automation Technologies Market Worth $74.8 Billion by 2019 - New Report by MarketsandMarkets 2Health News:Intelligent Building Automation Technologies Market Worth $74.8 Billion by 2019 - New Report by MarketsandMarkets 3Health News:Intelligent Building Automation Technologies Market Worth $74.8 Billion by 2019 - New Report by MarketsandMarkets 4Health News:Physical fitness associated with less pronounced effect of sedentary behavior 2Health News:Americas Transcatheter Heart Valves Market 2020 Forecasts in New Research Report at LifeScienceIndustryResearch.com 2Health News:Americas Transcatheter Heart Valves Market 2020 Forecasts in New Research Report at LifeScienceIndustryResearch.com 3Health News:Americas Transcatheter Heart Valves Market 2020 Forecasts in New Research Report at LifeScienceIndustryResearch.com 4Health News:Madison-based SWAMP, Secure Decisions partner to enhance software security 2Health News:Madison-based SWAMP, Secure Decisions partner to enhance software security 3
... made him the last of his line, researchers say ... powerful Habsburg royal family ruled Spain for centuries until the ... , Now, a new study suggests the reason for their ... and their unfortunate habit of marrying their own relatives. ...
... the highest level of excellence, achieving ASQ CQI Certifications. , ... ... Board of the American Society for Quality is pleased to announce ... completed the requirements to be named an ASQ-Certified Quality Inspector (ASQ ...
... 8 Saints Mary and Elizabeth Medical Center, 2233 ... Blue Cross and Blue Shield of Illinois, Childhood Health ... for children at risk for obesity and diabetes. This ... Obesity is an epidemic in the United States. Since ...
... 8 This Sunday, individuals all over the ... the women who gave them life: their mothers. While people ... the International Breast Milk Project (IBMP) hopes to inspire some ... organization that helps mothers in the United States send their ...
... Protect Patients and Consumers ROCKVILLE, Md., May 8 ... substantial increase in funding for the Food and ... budget. Following the Obama administration,s voiced support for ... increase the agency,s ability to protect American patients ...
... May 8 PRO-DEX, INC. (Nasdaq: PDEX ) ... of the Company,s fiscal 2009 third quarter financial results. The ... on Thursday, May 14, 2009 at 4:30 p.m. Eastern Time ... Company,s website at www.pro-dex.com . Mark ...
Cached Medicine News:Health News:Inbreeding May Have Doomed Spain's Habsburg Dynasty 2Health News:Inbreeding May Have Doomed Spain's Habsburg Dynasty 3Health News:Clinical Instrument Repair Consultants Receive ASQ-Certified Quality Inspector 2Health News:Blue Cross and Blue Shield Funds Diabetes Education at Saints Mary and Elizabeth Medical Center 2Health News:International Breast Milk Project Helps Mothers Worldwide 2Health News:USP Applauds President's Budget Support for FDA 2Health News:Pro-Dex, Inc. Announces Fiscal 2009 Third Quarter Financial Results Conference Call and Webcast 2
(Date:7/14/2014)... 14, 2014 Decision Resources Group finds ... influence perceptions of emerging drugs for both oncologists ... oncologists (50 medical oncologists and 50 hematological oncologists) ... managed care organizations (MCOs), reveals that despite lower ... majority of payers say this designation will likely ...
(Date:7/14/2014)... 2014  More than any other generation, Millennials born in ... -- but their eyes don,t. These mobile devices demand a ... the eye has not evolved to cope with them. The ... do comfortably often results in tired eyes, focusing problems, headaches ... Strain. Now ZEISS has invented a new type of lens ...
(Date:7/14/2014)... July 14, 2014  Diomics, Inc., provider of ... that the United States Patent and Trademark Office ... covering novel biologic sample collection materials, devices made ... forensics and diagnostics. The primary ... swabbing. Recovery of DNA from a number of ...
Breaking Medicine Technology:Breakthrough Therapy Designation is Likely to Sway Oncologists' Confidence in An Agent and Encourage Prescribing 2Breakthrough Therapy Designation is Likely to Sway Oncologists' Confidence in An Agent and Encourage Prescribing 3New Eyeglass Lens Helps Our Eyes Keep Up with our Digital Lives 2New Eyeglass Lens Helps Our Eyes Keep Up with our Digital Lives 3Diomics Announces Issuance Of U.S. Patents For Novel Biologic Sample DNA Collection Materials For Use In Forensics And Diagnostics 2