Navigation Links
Einstein scientists find crucial molecule involved in spread of breast cancer
Date:6/8/2011

June 8, 2011 (Bronx, NY) Researchers at Albert Einstein College of Medicine of Yeshiva University have identified a key player in the spread of breast cancer. The findings, published today in the online edition of Nature, identify a critical molecule that helps cancer spread beyond the primary tumor. The research highlights a potential new strategy against metastatic disease. The study's senior author is Jeffrey Pollard, Ph.D., professor of developmental and molecular biology and of obstetrics & gynecology and women's health at Einstein. He also holds the Louis Goldstein Swan Chair in Women's Cancer Research and is the deputy director of the Albert Einstein Cancer Center.

People rarely die from their primary (original) tumor. Instead, most cancer deaths occur because the cancer has spread, or metastasized, to other parts of the body. "By focusing on sites where cancer had spread, we were able to detect a molecule that stimulates metastasis," said Dr. Pollard. "This raises the possibility that metastasis could be kept from progressing or even prevented if the stimulating molecule could be blocked. This we achieved in mouse models of breast cancer."

Metastasis begins when cells break away from the primary tumor and gain the ability to move on their own. These cells invade nearby blood vessels (a process known as intravasation) and are carried by the bloodstream to other parts of the body. The bloodborne tumor cells then escape from vessels in a process known as extravasation. Once these tumor cells escape from the vessels, they seed new and deadly tumors that grow in these distant locations.

In previous studies, Dr. Polla
'/>"/>

Contact: Kim Newman
sciencenews@einstein.yu.edu
718-430-3101
Albert Einstein College of Medicine
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Einstein secures $11 million to continue research on brain aging and Alzheimers disease
2. Einstein Montefiore lung specialist to receive award for work with 9/11 rescue workers
3. Feinstein scientists identify abnormal disease pathway in dystonia
4. Susan Band Horwitz, Ph.D., of Einstein, receives lifetime achievement award in cancer research
5. Einstein-Montefiore researcher will test nanoparticles against pancreatic cancer
6. ALBERT EINSTEIN COLLEGE OF MEDICINE HELPS ADDRESS NEED FOR IMPROVED CANCER CARE IN RURAL AMERICA
7. Feinstein Institute to share $5M US Department of Defense grant
8. Einstein scientist awarded $4 million to develop genetic strategy to combat tuberculosis
9. Einstein awarded NIH grant to study drug-resistant TB
10. NIH awards $10M to Einstein for diabetes research
11. Scientists create humanized mouse model for hepatitis C
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/22/2014)... The United States is now mandating that all ... Africa land at one of five airports equipped ... In a statement released Tuesday, Homeland Security ... air passengers from Guinea, Liberia and Sierra Leone ... -- New York City,s Kennedy International Airport, Washington ...
(Date:10/22/2014)... 2014 Hay House is pleased to announce ... Upgrade Your Life (Paperback; $10.82) written by the highly esteemed ... This book is meant to help readers of all ... recovery. , Recovery 2.0 is not the average self-help ... is a guide for what comes next. For ...
(Date:10/22/2014)... Best Cheap Hosting USA is among the most ... recently announced that iPower ( http://www.best-cheap-hosting-usa.com/go/iPower/ ) is the ... the world. , “iPower is one of the most ... various kinds of useful products for new and old ... customer service and a number of features which will ...
(Date:10/22/2014)... Although there are only 24 hours in a ... who have trouble finding time within their busy schedules for exercise ... periods of time to get in shape. Here are five ways ... go. , Change Up Your Commute , Consider riding a ... some exercise into your daily routine. If you must use your ...
(Date:10/22/2014)... WALTHAM, MA (PRWEB) October 22, 2014 ... developing new solutions for the treatment of bacterial infections, ... J. Sinskey has joined its board of directors. ... Microbiology and Engineering Systems at The Massachusetts Institute of ... the MIT faculty since 1968. Dr. Sinskey also holds ...
Breaking Medicine News(10 mins):Health News:Passengers From Ebola-Affected Countries Must Land at Designated U.S. Airports 2Health News:Passengers From Ebola-Affected Countries Must Land at Designated U.S. Airports 3Health News:Hay House Announces The Official Release of Recovery 2.0: Move Beyond Addiction and Upgrade Your Life 2Health News:Hay House Announces The Official Release of Recovery 2.0: Move Beyond Addiction and Upgrade Your Life 3Health News:Best Cheap Hosting USA Has Recently Announced The Best Cheap Web Hosting Companies In 2014 2Health News:HealthGuideMD Presents Ways to Improve Your Exercise and Fitness 2Health News:Akeso Biomedical Appoints Dr. Anthony J. Sinskey to Board of Directors 2
... and Erosive ... Esophagitis, OSAKA, Japan, Oct. ... and,Development Center, Inc., a wholly owned United States (U.S.) subsidiary,received notification from ... able to complete its review of the TAK-390MR New,Drug Application (NDA) by ...
... Pulse Report Released Today, SOUTH BEND, Ind., ... report released today confirms patients have heightened expectations,of ... to choose where,they receive care. Health care facilities ... experience to maintain and improve patient retention,rates. The ...
... achievement, a feature story on Mary Hall will appear on ... ... 18, 2008 -- Mary Hall, CEO of iHealthspot, Inc. a leading ... membership into Fort Lauderdale City Limits "Profiles of Excellence" in the ...
... to Care in Underserved,Communities, SAN DIEGO, Oct. ... care to underserved residents of San Diego County,La ... the,expansion of its telemedicine program, thanks to a ... used to purchase new equipment including a camera,that ...
... TB, fight other drug-resistant bacteria , , FRIDAY, Oct. 17 ... perfecting a new class of broad-spectrum antibiotics that could ... , The new antibiotics compounds -- all of which ... other bacteria -- also show promise as a more ...
... Oct. 17 /PRNewswire-FirstCall/ - The Westaim Corporation,announced ... its wholly owned,subsidiary iFire Technology Ltd. and ... sell its equipment, patents and intellectual property,for ... sale is subject to,several conditions, including iFire ...
Cached Medicine News:Health News:FDA Adds Three Months to Review of Takeda's New Drug Application for TAK-390MR 2Health News:Report Confirms Consumer Selection is a Driving Force in Health Care Today 2Health News:Report Confirms Consumer Selection is a Driving Force in Health Care Today 3Health News:Mary Hall, CEO of iHealthSpot, Inc., is Awarded Membership Into Fort Lauderdale City Limits "Profiles of Excellence" 2Health News:La Maestra Community Health Centers Expands Telemedicine Program 2Health News:La Maestra Community Health Centers Expands Telemedicine Program 3Health News:Scientists Hot on Trail of New Antibiotics 2Health News:Westaim announces sale of iFire Technology Ltd. assets 2
(Date:10/22/2014)... YORK , Oct. 22, 2014 Sanomedics ... August 2014 report by Global Research & Data Services, ... per year from 2014 through 2018, as demand for ... States is the world,s largest market for ... with advanced thermometers is Sanomedics International Holdings, Inc. ...
(Date:10/22/2014)... REDWOOD CITY, Calif. , Oct. 22, 2014 ... ) today announced that results from the  IAP310 ... and Pain Medicine (RAPM), a peer-reviewed journal ... placebo-controlled, Phase 3 trial evaluating the safety and ... sufentanil sublingual tablet system (SSTS), for the treatment ...
(Date:10/20/2014)... , Oct. 20, 2014  PneumRx, Inc. ( ... pulmonology, today announced completion of enrollment in their RENEW ... Clinical Study is the FDA-approved IDE pivotal trial for ... emphysema. It was anticipated that the study, ... 2013, would take until the end of 2014 to ...
Breaking Medicine Technology:Sanomedics International Holdings Analyst Report: Taking Some Heat by BrokerBank Securities, Inc. 2AcelRx Announces Publication of Zalviso Phase 3 Abdominal Trial Results 2PneumRx Completes RENEW Pivotal Trial Enrollment 2PneumRx Completes RENEW Pivotal Trial Enrollment 3
... Pharmaceuticals, Inc. (Nasdaq: CADX ), a biopharmaceutical company ... principally for use in the hospital setting, announced today ... present the company,s corporate overview on Tuesday, October 27, ... the BIOCOM Investor Conference at the Hyatt Regency La ...
... , SAN DIEGO, Oct. 20 Anadys Pharmaceuticals, Inc. (Nasdaq: ... the BIOCOM Life Science Investor Conference on Monday, October 26, ... conference is being held at the Hyatt Regency La Jolla ... Chief Executive Officer of Anadys, will provide an overview of ...
Cached Medicine Technology:Anadys Pharmaceuticals to Present at Two Upcoming Investor Conferences 2
... The Sphincter of Oddi ... (PNET) works with the Polygraf™ ... and analyze pressure signals from ... The PNET software and Polygraf ...
... VoiceControl is a unique tool ... voice commands to activate shortcut ... eliminating the need to perform ... you can devote your full ...
... Analysis for POLYGRAM NET™ works with the ... analyze multichannel EGG signals. The EGG analysis ... by performing an automatic electrode impedance check ... beginning of a recording. If the electrode ...
... POLYGRAM NET™ (PNET) works with the ... analyze pressure and EMG signals from ... graphic format. The PNET software and ... or water-perfused manometry catheters as well ...
Medicine Products: