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Einstein-Montefiore researcher will test nanoparticles against pancreatic cancer
Date:1/3/2011

January 3, 2011 ─ (BRONX, NY) ─ A five-year, $16-million grant from the National Cancer Institute will take advantage of specialized expertise developed by scientists at Albert Einstein College of Medicine of Yeshiva University and Montefiore, the University Hospital and Academic Medical Center for Einstein. The research carried out by a group of five institutions, including Einstein, that comprise the Texas Center for Cancer Nanomedicine could lead to novel ways to diagnose and treat pancreatic and ovarian cancer using nanoparticles.

Nanoparticles are engineered materials that are 100 nanometers or less in size. (A nanometer is one billionth of a meter.) Nanoparticles impregnated with drugs are called nanomedicines.

"We will be investigating nanomedicines for both imaging and treating pancreatic tumors," said Einstein-Montefiore principal investigator Steven Libutti, M.D., professor and vice chair of surgery at Einstein and Montefiore, director of the Montefiore-Einstein Center for Cancer Care, and associate director for clinical services of the Albert Einstein Cancer Center. "Our part of the consortium is developing nanoparticles that will specifically target unique aspects of the blood vessels found in pancreatic adenocarcinomas and pancreatic neuroendocrine tumors."

Pancreatic cancer is the fourth-leading cause of all cancer deaths. Currently, there is no test for early detection of the disease, which killed nearly 37,000 people in 2010. Only 5.6 percent of people diagnosed with pancreatic cancer live for five years or longer, according to the National Cancer Institute.

Dr. Libutti has developed mice tha
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Contact: Kim Newman
sciencenews@einstein.yu.edu
718-430-3101
Albert Einstein College of Medicine
Source:Eurekalert

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