Navigation Links
Egg allergy: Not a reason to avoid flu vaccine after all
Date:10/18/2010

ANN ARBOR, Mich. Having an egg allergy is not a reason to avoid getting the 2010-2011 flu vaccination.

According to new recommendations by the American Academy of Allergy, Asthma & Immunology website, anyone with a history of suspected egg allergy should first be evaluated by an allergist or immunologist for appropriate testing and diagnosis but can probably receive the vaccination.

Matthew J. Greenhawt, M.D., M.B.A., clinical lecturer at the University of Michigan Health System and James T. Li, M.D., Ph.D., chair of the Division of Allergic Diseases in the Department of Internal Medicine at Mayo Clinic, co-authored the guidelines based on recent studies one conducted at the University of Michigan - that show that most egg-allergic individuals can receive the flu vaccine safely under the care of their allergist/immunologist.

In the past, people with egg allergy were told not to get the influenza vaccine because the vaccine contained egg protein and could trigger an allergic reaction. Research in the past year shows that influenza vaccines contain only tiny amounts of egg protein. Clinical studies have shown that the vast majority of persons with egg allergies did not experience a reaction when immunized with the influenza vaccine.

The safety of administering egg-containing immunizations to egg-allergic children and adults received new interest during the recent global pandemic of the H1N1 Influenza A virus in 2009-2010.

The H1N1 Influenza A vaccine (H1N1), like the seasonal Trivalent Influenza Vaccine (TIV) is grown on embryonated chicken eggs, which led to concerns that residual contamination of ovalbumin could provoke allergic reactivity in people with egg allergies. The 2010 influenza vaccine has incorporated the H1N1 strains. A single TIV is being offered this season.

Historically, though caution has been recommended in administering influenza vaccine to egg-allergic individuals, previous experience suggests that many people with diagnosed or suspected egg allergy can receive influenza vaccination successfully, if precautions are followed.

Examples of precautions that have been used include vaccine skin testing, a 2-step graded dose (10%, followed by 90% of the age appropriate dose after a brief observation period), or stepwise desensitization.

Given the urgency to protect children last year from the global influenza pandemic, investigative groups have re-examined the issue of the safety of this vaccine in egg-allergic people, and the field has advanced significantly since the last influenza season.

According to the new recommendations, the authors no longer recommend the practice of skin testing to the seasonal Trivalent Influenza Vaccine (TIV), although it may be useful as an extra level of caution in cases where the patient has a documented history of a past allergic reaction to the vaccine.

Anyone with a history of suspected egg allergy should first be evaluated by an allergist or immunologist for appropriate testing and diagnosis. Patients with a confirmed egg allergy can then receive the vaccine safely using one of two protocols: a two-step graded challenge or a single, age-appropriate dose.

"It is not necessary to withhold influenza vaccination from egg-allergic patients, says Greenhawt. "Our recommendations provide two flexible approaches to vaccination. Each approach is backed with recent evidence that it is safe. Most allergists should be able to identify with one of our recommended approaches, and as such, be able to vaccinate their egg-allergic patients with confidence."

Greenhawt notes that the safety of these vaccines in individuals with severe egg allergy needs to be studied further.

A few concepts bear further study, such as the safety of these vaccines in individuals with severe allergy to egg, but it appears that most egg-allergic patients can safely receive influenza vaccination if desired, Greenhawt says. Greenhawt is the lead investigator on a follow-up study that looks at the vaccine's safety in severely egg-allergic patients.

Providers should no longer withhold the vaccine on account of a patient's egg allergy, and should feel comfortable selecting the precautionary strategies for administering the influenza vaccine, he adds.


'/>"/>

Contact: Margarita B. Wagerson
mbauza@umich.edu
734-764-2220
University of Michigan Health System
Source:Eurekalert

Related medicine news :

1. Another Reason to Buy a Hot Tub: Bullfrog Donates Spa to Humanitarian Effort
2. Studies of womens attitudes to social egg freezing find reasons differ with age
3. Study examines reasons patients with early stage lung cancer do not have surgery
4. Ear Infection is the Most Common Reason Why an American Child Sees the Doctor
5. A Thousand New Reasons to Love Uni K Wax Centers Earn 5,000 Points for Referring A Friend New Rewards Program and New Centers
6. Research validates surgery alone offers reasonable overall survival for stage I SCLC
7. Diagnostic techniques help IBD patients avoid ionizing radiation exposure
8. Experimental obesity drug avoids brain effects that troubled predecessors
9. Employers took many measures to protect employees and avoid business impact of H1N1 flu outbreak
10. Avoid Becoming Social Media Roadkill: Top 5 Ways to Combat Negative Word of Mouth (Free Webinar)
11. Limiting blood flow interruption during kidney surgery avoids chronic kidney disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/28/2016)... ... 28, 2016 , ... "Color Grading media can be time consuming but with ... media," said Christina Austin - CEO of Pixel Film Studios. , With the ... stylish color grades to their footage. A LUT is a Lookup Table that contains ...
(Date:5/27/2016)... ... ... Southland Log Homes , designer and manufacturer of America’s Favorite Log Home™, ... found on its website at SouthlandLogHomes.com. , The designs of the wood barn ... of timber post and beam construction. The result is a barn that not ...
(Date:5/27/2016)... ... 27, 2016 , ... This campaign aims to provide a path to improved ... can control and change. , As nearly 795,000 Americans suffering from a new or ... States. Plus, with an estimated 129,000 of these people dying from stroke, it’s become ...
(Date:5/27/2016)... ... 2016 , ... Aimed at nurses and employees in the health care world, ... in the nursing and health care industry. It also provides insight to the developing ... , As the nursing industry is coming out of one of the biggest ...
(Date:5/26/2016)... ... 2016 , ... W.S. Badger Co. Inc ., the maker of certified ... Work Works Award for its use of effective workplace strategies to increase business and ... administered by the Families and Work Institute (FWI) and the Society for Human Resource ...
Breaking Medicine News(10 mins):
(Date:5/24/2016)... , May 24, 2016  NxStage Medical, Inc. (Nasdaq: ... focused on advancing renal care, today announced that ... participate in the following schedule of investor conferences. Where ... available at http://ir.nxstage.com/ .   ... Healthcare Conference NY, NY           Friday, June 10, 2016 ...
(Date:5/24/2016)... -- The innovator of COMBO ... s first dual therapy stent, introduces catheters for lower ... a global company specializing in the provision of life-changing ... to treat peripheral artery disease. The JADE™ and Scoreflex™ ... lower limb and arteriovenous (AV) fistula intervention. ...
(Date:5/24/2016)... England , May 24, 2016 ... and Education in Clinical Neurophysiology  Elsevier ... information products and services, today announced the launch of ... an open access journal that focuses on clinical practice ... research, case reports, clinical series, normal values and didactic ...
Breaking Medicine Technology: