Navigation Links
Egg allergy: Not a reason to avoid flu vaccine after all
Date:10/18/2010

ANN ARBOR, Mich. Having an egg allergy is not a reason to avoid getting the 2010-2011 flu vaccination.

According to new recommendations by the American Academy of Allergy, Asthma & Immunology website, anyone with a history of suspected egg allergy should first be evaluated by an allergist or immunologist for appropriate testing and diagnosis but can probably receive the vaccination.

Matthew J. Greenhawt, M.D., M.B.A., clinical lecturer at the University of Michigan Health System and James T. Li, M.D., Ph.D., chair of the Division of Allergic Diseases in the Department of Internal Medicine at Mayo Clinic, co-authored the guidelines based on recent studies one conducted at the University of Michigan - that show that most egg-allergic individuals can receive the flu vaccine safely under the care of their allergist/immunologist.

In the past, people with egg allergy were told not to get the influenza vaccine because the vaccine contained egg protein and could trigger an allergic reaction. Research in the past year shows that influenza vaccines contain only tiny amounts of egg protein. Clinical studies have shown that the vast majority of persons with egg allergies did not experience a reaction when immunized with the influenza vaccine.

The safety of administering egg-containing immunizations to egg-allergic children and adults received new interest during the recent global pandemic of the H1N1 Influenza A virus in 2009-2010.

The H1N1 Influenza A vaccine (H1N1), like the seasonal Trivalent Influenza Vaccine (TIV) is grown on embryonated chicken eggs, which led to concerns that residual contamination of ovalbumin could provoke allergic reactivity in people with egg allergies. The 2010 influenza vaccine has incorporated the H1N1 strains. A single TIV is being offered this season.

Historically, though caution has been recommended in administering influenza vaccine to egg-allergic individuals, previous experience suggests that many people with diagnosed or suspected egg allergy can receive influenza vaccination successfully, if precautions are followed.

Examples of precautions that have been used include vaccine skin testing, a 2-step graded dose (10%, followed by 90% of the age appropriate dose after a brief observation period), or stepwise desensitization.

Given the urgency to protect children last year from the global influenza pandemic, investigative groups have re-examined the issue of the safety of this vaccine in egg-allergic people, and the field has advanced significantly since the last influenza season.

According to the new recommendations, the authors no longer recommend the practice of skin testing to the seasonal Trivalent Influenza Vaccine (TIV), although it may be useful as an extra level of caution in cases where the patient has a documented history of a past allergic reaction to the vaccine.

Anyone with a history of suspected egg allergy should first be evaluated by an allergist or immunologist for appropriate testing and diagnosis. Patients with a confirmed egg allergy can then receive the vaccine safely using one of two protocols: a two-step graded challenge or a single, age-appropriate dose.

"It is not necessary to withhold influenza vaccination from egg-allergic patients, says Greenhawt. "Our recommendations provide two flexible approaches to vaccination. Each approach is backed with recent evidence that it is safe. Most allergists should be able to identify with one of our recommended approaches, and as such, be able to vaccinate their egg-allergic patients with confidence."

Greenhawt notes that the safety of these vaccines in individuals with severe egg allergy needs to be studied further.

A few concepts bear further study, such as the safety of these vaccines in individuals with severe allergy to egg, but it appears that most egg-allergic patients can safely receive influenza vaccination if desired, Greenhawt says. Greenhawt is the lead investigator on a follow-up study that looks at the vaccine's safety in severely egg-allergic patients.

Providers should no longer withhold the vaccine on account of a patient's egg allergy, and should feel comfortable selecting the precautionary strategies for administering the influenza vaccine, he adds.


'/>"/>

Contact: Margarita B. Wagerson
mbauza@umich.edu
734-764-2220
University of Michigan Health System
Source:Eurekalert

Related medicine news :

1. Another Reason to Buy a Hot Tub: Bullfrog Donates Spa to Humanitarian Effort
2. Studies of womens attitudes to social egg freezing find reasons differ with age
3. Study examines reasons patients with early stage lung cancer do not have surgery
4. Ear Infection is the Most Common Reason Why an American Child Sees the Doctor
5. A Thousand New Reasons to Love Uni K Wax Centers Earn 5,000 Points for Referring A Friend New Rewards Program and New Centers
6. Research validates surgery alone offers reasonable overall survival for stage I SCLC
7. Diagnostic techniques help IBD patients avoid ionizing radiation exposure
8. Experimental obesity drug avoids brain effects that troubled predecessors
9. Employers took many measures to protect employees and avoid business impact of H1N1 flu outbreak
10. Avoid Becoming Social Media Roadkill: Top 5 Ways to Combat Negative Word of Mouth (Free Webinar)
11. Limiting blood flow interruption during kidney surgery avoids chronic kidney disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... SAN LUIS OBISPO, Calif. (PRWEB) , ... October 13, 2017 , ... ... with Alzheimer’s or dementia. However, many long-term care insurance companies have a waiver for ... mean is the 90-day elimination period, when the family pays for care, is often ...
(Date:10/13/2017)... ... October 13, 2017 , ... Yisrayl Hawkins, Pastor and Overseer at The House ... most popular and least understood books in the Holy Scriptures, Revelation. The Book of ... baffled scholars for centuries. Many have tossed it off as mere rubbish, but Yisrayl ...
(Date:10/13/2017)... , ... October 13, 2017 , ... “America On The ... identity. “America On The Brink” is the creation of published author, William Nowers. ... great-grandchildren. As a WWII veteran, he spent thirty years in the Navy. ...
(Date:10/12/2017)... ... 2017 , ... The company has developed a suite of ... authorities worldwide. From Children’s to Adults 50+, every formula has been developed by ... , These products are also: Gluten Free, Non-GMO, Vegan, Soy Free, Non-Dairy*, Preservative ...
(Date:10/12/2017)... ... 12, 2017 , ... Information about the technology: , Otomagnetics ... enable prevention of a major side effect of chemotherapy in children. Cisplatin and ... For cisplatin, hearing loss is FDA listed on-label as a dose limiting toxicity. ...
Breaking Medicine News(10 mins):
(Date:10/2/2017)... FLINT, Mich. , Oct. 2, 2017 ... acquired 8th Day Software and Consulting, LLC , ... 8th Day Software, based in Tennessee ... Management LLC. 8th Day expands EnvoyHealth,s service offerings for ... product development. "In ...
(Date:10/2/2017)... 2, 2017 The Rebound mobile app is poised ... reverse the tide of prescription drug addiction. The app empowers ... intake and stepping down their dosage in a safe, controlled ... December 2017; the first 100,000 people to sign up will ... http://www.rebound-solution.com/ ...
(Date:9/27/2017)... Israel and NEW YORK , Sept. 27, ... with mobile health and big data solutions, today announced that its MyDario ... Please check your local TV listings for when The Dr. Oz Show ... ... season this month. ...
Breaking Medicine Technology: