Navigation Links
Effects of High Blood Pressure Drug May Mimic Celiac Disease
Date:6/22/2012

FRIDAY, June 22 (HealthDay News) -- A new report suggests that the common blood pressure drug olmesartan (Benicar) can cause symptoms that mimic celiac disease, leading to misdiagnosis and unnecessary treatment.

It's not clear how often people who take the blood pressure-lowering drug will develop the gastrointestinal problems that are similar to those caused by celiac disease. For the moment, though, the side effects appear to be unusual, said Dr. Peter Green, director of the Celiac Disease Center at Columbia University Medical School, who was not involved with the study.

Still, Green noted, his center has seen patients who developed celiac disease-like symptoms while taking olmesartan and some have been quite ill. "One went into kidney failure and needed dialysis," he said.

According to the new study from the Mayo Clinic in Rochester, Minn., 22 patients -- aged 47 to 81, average age 70 -- had symptoms of chronic diarrhea and weight loss of an average of 40 pounds. Fourteen of the patients needed to be hospitalized.

Tests showed that these patients didn't have celiac disease, a condition that causes gastrointestinal problems due to an allergy to gluten, which is found in products such as wheat and rye. However, all of the patients were taking olmesartan.

After they stopped taking the drug, all of the patients' symptoms improved; all but three went on to take other blood pressure medications.

It is not clear why the drug may cause the gastrointestinal symptoms, the study authors noted in the report published online June 21 in the Mayo Clinic Proceedings.

"These patients are usually elderly and have been on the drug for quite some time," said Green. Researchers should continue exploring the issue, he suggested.

While the study uncovered an association between celiac disease-like symptoms and use of olmesartan, it did not prove a cause-and-effect relationship.

"We thought these cases were celiac disease initially because their biopsies showed features very like celiac disease, such as inflammation," study author Dr. Joseph Murray, a Mayo Clinic gastroenterologist, said in a news release from the clinic. "What made them different was they didn't have the antibodies in their blood that are typical for celiac disease."

"It's really an awareness issue. We want doctors to be aware of this issue, so if they see a patient who is having this type of syndrome, they think about medications as a possible association," Murray said. "We've reported an association. What needs to be known next is the science to understand why there is such an association."

More information

For more on celiac disease, visit the U.S. National Library of Medicine.

-- Randy Dotinga

SOURCES: Peter Green, M.D., director, Celiac Disease Center, and professor of clinical medicine, Columbia University Medical School, New York City; Mayo Clinic, news release, June 21, 2012; June 21, 2012, Mayo Clinic Proceedings, online


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Young girls more likely to report side effects after HPV vaccine
2. Preteens More Likely to Report HPV Vaccine Side Effects
3. Breast cancer patients suffer treatment-related side effects long after completing care
4. Breast Cancer Treatment Side Effects May Last for Years
5. Baldness Drug May Cause Sexual Side Effects: FDA
6. Study examines adverse effects among different radiation therapies for prostate cancer
7. LA BioMeds Dr. John Tsuang examines effects of Ibudilast and metamphetamines
8. Moffitt researcher publishes book on nutritional management of cancer treatment effects
9. Researchers see BPA effects in monkey mammary glands
10. Many Primary Care Docs Dont Know Long-Term Effects of Chemo: Survey
11. Dartmouth researchers investigate the cognitive effects of athlete head impacts
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Effects of High Blood Pressure Drug May Mimic Celiac Disease
(Date:12/9/2016)... PITTSBURGH, PA (PRWEB) , ... December 09, 2016 , ... ... would permit amputees to safely ride all types of amusement park rides. , The ... Additionally, the unit is easy to use and could be set up in a ...
(Date:12/9/2016)... ... December 09, 2016 , ... ... Pennsylvania Cable Network (PCN) during the summer of 2016. The program was made ... by the United States Department of Health and Human Services Administration. The ...
(Date:12/8/2016)... ... December 08, 2016 , ... ZyDoc , a ... and Conventional Data Capture Methods for Input to Electronic Health Records: A Comparative ... of the comparative usability study demonstrate that a dictation-based method (“NLP Entry”) using ...
(Date:12/8/2016)... ... December 08, 2016 , ... David J. Dykeman , Ginger ... Traurig, LLP, will speak at DeviceTalks West, Dec. 12, 2016, at the Fairmont Newport ... attorneys from the firm’s global Life Sciences & Medical Technology Group have been featured ...
(Date:12/8/2016)... ... ... STATEN ISLAND, N.Y., Nov. 24, 2016 — Richmond ... of trauma, maternity, cancer and chronic obstructive pulmonary disease (COPD) services from three ... , Among the recognitions, the American College of Surgeons' (ACS) named the hospital's ...
Breaking Medicine News(10 mins):
(Date:12/9/2016)... , Dec. 9, 2016   Hudes Laser ... December featuring the multi-wavelength Astanza Trinity laser and ... specializes in laser tattoo removal, IPL hair removal, ... ultrasound therapy. Hudes Laser Aesthetica is setting high ... and promises to deliver effective, long-lasting ...
(Date:12/9/2016)... OSAKA, Japan , Dec. 9, 2016 ... ; President & Representative Director, CEO: Dr. ... with amyotrophic lateral sclerosis (ALS) given edaravone intravenously in ... functional loss as measured by the ALS Functional Rating ... th International Symposium on ALS/MND in ...
(Date:12/9/2016)... 9, 2016  Axovant Sciences Ltd. (NYSE: ... focused on the treatment of dementia, today announced ... Phase 2b trial evaluating treatment with intepirdine (RVT-101), ... donepezil plus placebo in people with mild-to-moderate Alzheimer,s ... intepirdine to treatment was associated with reduced progression ...
Breaking Medicine Technology: