Navigation Links
Effectiveness of Progesterone in Reducing Preterm Births May Be Altered by Genetic Predisposition
Date:1/29/2009

-Fetal Medicine Unit Network and the University of Utah, assessed whether women with genetic variations known as single nucleotide polymorphisms (SNPs) in the human progesterone receptor gene were more or less likely to respond to 17P for the prevention of recurrent spontaneous preterm birth.

All patients had at least one prior spontaneous preterm birth. The study extracted DNA from the saliva of 389 patients, and then genotyped 20 SNPs in the region of the progesterone receptor gene. Two hundred and fifty-eight (66 percent) of the study participants received 17P and 131 (34 percent) were controls and received a placebo.

Spontaneous preterm birth was less common among women who received 17P. However, after controlling for factors known to be associated with recurrent prematurity, including smoking, number of prior preterm deliveries, and pre-pregnancy body mass index, two SNPs were identified among African-American patients to be predictive of response to progesterone treatment. There was also an interaction between progesterone treatment and genotype of 3 additional polymorphisms for non-African-American women delivering very preterm (less than 32 weeks gestation).

Today's award-winning study, The Relationship Between Polymorphisms in the Human Progesterone Receptor and Clinical Response to 17 Alpha-Hydroxyprogesterone Caproate for the Prevention of Recurrent Spontaneous Preterm Birth, is the sixth study by SMFM members to be honored by the March of Dimes for innovative research focused on preventing premature births. The March of Dimes is conducting a multi-year, multi-million dollar campaign aimed at using research and awareness to reduce the growing rate of premature birth.

The Society for Maternal-Fetal Medicine (est. 1977) is a non-profit membership group for obstetricians/gynecologists who have additional formal education and training in maternal-fetal medicine
'/>"/>

SOURCE March of Dimes
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine news :

1. Statement on Comparative Effectiveness Research Under Senate Appropriations Committee Stimulus Bill
2. Comparative Effectiveness Research Must Put Patients First
3. InNexus Biotechnology Completes Preclinical Study Confirming in Vivo Effectiveness and Safety of Lead Candidate DXL625, Schedules Meeting With FDA
4. Comparative Effectiveness Research Tools Address Variations in corporate spending
5. Mayo researchers offer new insight into effectiveness of procedure to stop heavy menstrual bleeding
6. Haemacures Human Fibrin Sealant Demonstrates Effectiveness in Skin Graft Fixation Proof-of-Concept Study for Burn Injury
7. Integrated Benefits Institute Announces Availability of 2007 IBI Benchmarking Data for Employers to Evaluate Effectiveness of their Health and Productivity Programs
8. Naturally Safe Cold Remedy Challenges Effectiveness of Over-The-Counter Cold Medications
9. New Study Demonstrates Cost Effectiveness of NeuroStar TMS Therapy(R) in the Treatment of Depression
10. WorldHeart Announces Effectiveness of Reverse Stock Split
11. Genes influence effectiveness of weight-loss drug
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/28/2015)... 28, 2015 Take a bite of ... into action. Acids tumble into the stomach, ready to ... valve-like structure lets these acids run amok, triggering a ... common symptom. More than 60 million Americans have heartburn ... where heartburn starts, and how it can be stopped. ...
(Date:3/28/2015)... March 28, 2015 Emergency Medical Care ... care in Manhattan, recently commemorated its three-year anniversary of ... Manhattan. In addition to 24-hour urgent care, Emergency Medical ... , At this time, Emergency Medical Care’s Urgent ... asthma, chest pain, eye injuries, ear infections, fevers, insect ...
(Date:3/28/2015)... Pitching speed, player’s height, and pitching for multiple teams ... according to new research released today at the American Orthopaedic ... “Our findings indicate that a 10 inch increase in height ... history of injury, a 10 mile per hour increase in ... history of injury, and playing for more than one team ...
(Date:3/28/2015)... 28, 2015 Early surgery may not ... V AC joint injuries, according to new research from ... the American Orthopaedic Society for Sports Medicine’s ( AOSSM ... faster when surgery was not performed. , The final ... surgical treatment and 17 receiving non-surgical therapy. Of the ...
(Date:3/28/2015)... (PRWEB) March 28, 2015 Aureus ... healthcare staffing, including physical therapy jobs, has announced ... the Ohio Physical Therapy Association Annual Conference to ... Columbus Downtown Hotel in Columbus, OH. , ... opportunities, and exhibits with products and services. ...
Breaking Medicine News(10 mins):Health News:Bypass Your Heartburn Worries This Easter With Tylers Coffee 2Health News:Emergency Medical Care Celebrates Three Years of 24/7 Walk-In Urgent Care Services 2Health News:Researchers Highlight Shoulder and Elbow Injury Possibility in Youth Players 2Health News:For Type V AC Joint Injuries, Early Surgery May Not Be the Best Approach 2Health News:Healthcare Staffing Leader, Aureus Medical Group, to Exhibit at the Ohio Physical Therapy Association Annual Conference 2
... 2007, the progress made in the 1990s and early ... pregnancy and childbearing stalled, and may even have reversed ... "Changing Behavior Risk for Pregnancy Among High School Students ... MD, MPH, professor and chair of the Heilbrunn Department ...
... different approach to choosing the best treatment options for early ... experts in a report from the 11th St Gallen conference. ... Annals of Oncology [1] today (Thursday 18 June), ... emerged from the conference of more than 4,800 participants from ...
... May Lead to Elimination of Specialty Care Programs , ... Chicago is preparing to notify hundreds of clients that its ... soon disappear, if the State of Illinois,s "50% budget" comes ... and individuals with epilepsy to a full range of medical, ...
... and Food-Related Health Emphasized , , CHICAGO, June 17 ... policy resolution in support of practices and policies within health ... sustainable food system. The resolution also calls on the AMA ... educate the health care community and the public about the ...
... radiation therapy have a substantially higher risk of stroke, according ... Journal of the National Cancer Institute . ... stroke and transient ischemic attack (TIA), or a "mini stroke," ... the long-term risks, Flora E. van Leeuwen, Ph.D., of the ...
... of the future could be smaller, faster, more powerful ... researchers at the Department of Energy,s Oak Ridge National ... Science , involves a method to measure intrinsic ... held tremendous promise but have eluded experimental proof. Now, ...
Cached Medicine News:Health News:Teens are heading in wrong direction: Likely to have sex, but not use contraception 2Health News:St. Gallen consensus 2009: A radically different approach to treating early breast cancer 2Health News:St. Gallen consensus 2009: A radically different approach to treating early breast cancer 3Health News:Epilepsy Services on the Chopping Block 2Health News:American Medical Association Passes Resolution Supporting Sustainable Food System 2Health News:American Medical Association Passes Resolution Supporting Sustainable Food System 3Health News:Hodgkin lymphoma survivors have increased risk of stroke and transient ischemic attack 2Health News:ORNL finding could help electronics industry enter new phase 2
(Date:3/27/2015)... 2015 Object recognition technology has a unique ... elderly. The VelaSense ® mobile platform ... independent, productive and fulfilling lives. VelaSense ® will ... to identify objects from a one million object database, ... object databases for personal use. Visus ...
(Date:3/27/2015)... /CNW Telbec/ - Russell Williams , President of ... welcomes the 2015-2016 Quebec Budget, noting the fiscal discipline ... biopharmaceutical industry. However, the association is concerned about the ... the government,s intent to strive for a balanced budget ... Quebec,s economic development is encouraging," ...
(Date:3/27/2015)... Texas , March 27, 2015  Victoria Vein & ... services with the Astanza Duality laser in Victoria, ... vein disease as well as advanced laser treatments for a ... entering the tattoo industry to provide more services for their ... has helped many Victoria residents get ...
Breaking Medicine Technology:VelaSense Object Recognition Technology for the Blind was unveiled at Baruch College's CCVIP 8th Annual Conference 2Quebec 2015-2016 Budget: Rx&D welcomes fiscal discipline and biopharma working group, but the decrease in government spending on medicines is questioned 2Quebec 2015-2016 Budget: Rx&D welcomes fiscal discipline and biopharma working group, but the decrease in government spending on medicines is questioned 3Victoria Vein And Surgery Clinic Uses Advanced Astanza Duality Tattoo Removal Technology 2
Manufactured with a radiopaque line running down the length of the tube, position can be easily visualized by x-ray....
The all silicone construction of the shaft and neck flange provides the utmost in patient comfort. , ,The Aire-Cuf® tracheostomy tube offers a more traditional and familiar air-filled cuff desig...
... Extra vertical length tubes are often ... fistulas, stenosis, and tracheal malacia. Available ... features two independently inflatable cuffs. Greater ... possible since cuff sites can be ...
... Bivona® Mid-Range Aire-Cuf® Adjustable Neck ... TTS™ tube except this tube features ... Aire-Cuf®., ,Adult Mid-Range Aire-Cuf® Adjustable ... a trach tie, disconnect wedge, and ...
Medicine Products: