Navigation Links
Effect of medication is affected by copies of genetic information
Date:4/10/2013

The results may help to explain why certain medications have strong side effects on sperm and eggs, and why certain organisms remain unaffected by environmental changes. This is shown by studies that researchers from the University of Gothenburg, together with researchers from Norway and France, are now publishing in the journal PLOS Genetics.

All cells in our bodies contain copies of the genetic information. However, different cells contain different numbers of the complete genetic information. Normal human cells usually contain two copies of the genetic information, and thus two copies of every gene. Eggs and sperm, however, only contain one set of genes.

"At the same time, the cells of many plants and amphibians contain many more copies of genetic information, and the number of copies can also vary during an organism's development and between different stages of life," explains Jonas Warringer, a researcher at the University of Gothenburg's Department of Chemistry and Molecular Biology.

Research has often overlooked this variation in genetic information. However, Jonas Warringer and his colleagues have now used ordinary baker's yeast to show that the number of copies of genetic information has a decisive effect on the properties of cells.

Jonas and his colleagues collected yeast samples from around the world and created two variants of each yeast culture one with two copies of the genetic information, and the other with just one copy. The researchers then examined the properties of these yeast cells, such as their tolerance to cancer medication and antibiotics. The study, which is reported on in the journal PLOS One, shows that the number of copies of genetic information has a decisive effect on the properties of cells.

"The cells with two copies of genetic information showed greater tolerance to some substances," continues Jonas, "while in other cases those with only one copy had an advantage. Surprisin
'/>"/>

Contact: Jonas Warringer
jonas.warringer@cmb.gu.se
46-073-022-6322
University of Gothenburg
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Young girls more likely to report side effects after HPV vaccine
2. Preteens More Likely to Report HPV Vaccine Side Effects
3. In children born with severe heart defect, surgical management has little effect on neuro outcomes
4. Novel compound demonstrates anti-leukemic effect in zebrafish, shows promise for human treatment
5. Breast cancer patients suffer treatment-related side effects long after completing care
6. Breast Cancer Treatment Side Effects May Last for Years
7. Baldness Drug May Cause Sexual Side Effects: FDA
8. Study examines adverse effects among different radiation therapies for prostate cancer
9. HIV Prevention Pill Cost-Effective for High-Risk Men: Study
10. Pig stomach mucins are effective as anti-viral agents for consumer products
11. LA BioMeds Dr. John Tsuang examines effects of Ibudilast and metamphetamines
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/30/2014)... Researchers at the Monterey Bay Aquarium Research Institute (MBARI) ... four and one half yearslonger than any other known ... clean and guarded them from predators. This amazing feat ... the young octopuses of having plenty of time to ... survive for years with little or no food. , ...
(Date:7/30/2014)... 30, 2014 Frozen shoulder (Adhesive capsulitis) affects ... to develop this nasty condition which occurs most frequently in ... last up to two and half years if not treated. ... and with good reason: it can render your shoulder so ... is, if you aren't in too much pain to get ...
(Date:7/30/2014)... (HealthDay News) -- For patients with asthma, just believing ... airway inflammation for at least 24 hours, a new ... but also what you think you smell," study author ... in Philadelphia, said in a Monell news release. ... When we expect that an odor is harmful, our ...
(Date:7/30/2014)... --,Although the vast majority of kids with autism have ... differently from children who have trouble processing sensory stimuli, ... can be overly sensitive to sound, sight and touch. ... a lack of concentration. Complicating matters, some kids ... have trouble tolerating loud noises, like a vacuum. Others ...
(Date:7/30/2014)... adults who were breastfed for three months or ... of chronic inflammation associated with cardiovascular and metabolic ... at Washington University in St. Louis. , "This ... implications for children,s health decades later," said Molly ... School and a co-author of the study with ...
Breaking Medicine News(10 mins):Health News:Deep-sea octopus broods eggs for over 4 years -- longer than any known animal 2Health News:Deep-sea octopus broods eggs for over 4 years -- longer than any known animal 3Health News:Good News for Diabetics Suffering from Frozen Shoulder 2Health News:Good News for Diabetics Suffering from Frozen Shoulder 3Health News:Good News for Diabetics Suffering from Frozen Shoulder 4Health News:Even Thinking an Odor is Harmful May Spur Asthma Symptoms 2Health News:Different Areas of Brain Affected in Autism, Sensory Disorders 2Health News:Different Areas of Brain Affected in Autism, Sensory Disorders 3Health News:Birthweight and breastfeeding have implications for children's health decades later 2
... ... Dr. Howard Herman, M.D., a physician with the Atlanta Snoring Institute, ... importance of paying attention to sinus pain in order to prevent infection, ... nose, and throat doctor and head and neck surgeon at the Atlanta ...
... ... Hearing Healthcare Provider , ... Bonita Springs, FL (PRWEB) October 28, 2009 -- PHSI (Physician Hearing ... ophthalmologists with the tools needed to care for an ever-growing demographic of patients. ...
... ... platforms , ... -- New York Merchants Protective Co., Inc. , is proud to announce it will ... . , , , , ,NYMPC has been approved as an authorized Geutebruck solutions provider, ...
... , OAK BROOK, Ill., Oct. 28 Understanding the ... for health care providers, including enhancing safety and helping ... malpractice litigation. In fact, many academic medical centers are ... to improve the quality of care for patients. ...
... 27 Addus HomeCare Corporation announced today that it has ... common stock at $10.00 per share. Addus shares will ... Market under the ticker symbol "ADUS". The closing of ... 2009. Addus expects to receive net proceeds from the ...
... , TUESDAY, Oct. 27 (HealthDay News) -- Combining chemotherapy ... neck cancer increases their event-free survival to 2.2 years ... new study. , According to the study authors, "events" ... researchers looked at the 10-year outcomes of 966 patients ...
Cached Medicine News:Health News:Atlanta Snoring Institute Doctor Provides Expert Advice on Relief of Flu Symptoms and Prevention of Sinus Infection 2Health News:Atlanta Snoring Institute Doctor Provides Expert Advice on Relief of Flu Symptoms and Prevention of Sinus Infection 3Health News:Atlanta Snoring Institute Doctor Provides Expert Advice on Relief of Flu Symptoms and Prevention of Sinus Infection 4Health News:PHSI, INC. Develops Revolutionary Vision-Hearing Program 2Health News:New York Merchants Protective Co. Designated as Authorized Geutebruck Solutions Provider 2Health News:New York Merchants Protective Co. Designated as Authorized Geutebruck Solutions Provider 3Health News:UHC Benchmarking Project Focuses on Patient- and Family-Centered Care in Academic Medical Centers 2Health News:UHC Benchmarking Project Focuses on Patient- and Family-Centered Care in Academic Medical Centers 3Health News:Addus HomeCare Corporation Prices Initial Public Offering 2Health News:Adding Chemo Helps Head, Neck Cancer Patients 2
(Date:7/30/2014)... Fla. , July 30, 2014  Today the US ... indoor and outdoor sun tanning or sun burns stating they ... statement Surgeon, General Boris Lushniak , says that "skin ... types and that too much exposure to indoor and outdoor ... for Dermatology and Aesthetic Medicine, in Boca Raton, ...
(Date:7/30/2014)... , July 30, 2014  El Camino Hospital, a ... care, is utilizing the Leaf Patient Monitoring system to ... and movement of patients susceptible to bed sores. ... month-long, 138-patient study of the system, which showed dramatic ... Turning patients regularly is the one of the most ...
(Date:7/30/2014)... YORK , July 30, 2014 ... is available in its catalogue: mHealth ... http://www.reportlinker.com/p0356852/mHealth-and-Home-Monitoring-–-6th-Edition.html Executive summary ... are delivered, leading to better outcomes, decreased costs ... market for mHealth solutions is still in an ...
Breaking Medicine Technology:Indoor and Outdoor Sun Tanning or Sun Burns Directly Linked to Deadly Melanoma Skin Cancer 2El Camino Hospital Utilizes Cutting-Edge Leaf Patient Monitor System to Help Reduce Risk of Pressure Ulcers 2El Camino Hospital Utilizes Cutting-Edge Leaf Patient Monitor System to Help Reduce Risk of Pressure Ulcers 3mHealth and Home Monitoring - 6th Edition 2mHealth and Home Monitoring - 6th Edition 3mHealth and Home Monitoring - 6th Edition 4mHealth and Home Monitoring - 6th Edition 5mHealth and Home Monitoring - 6th Edition 6mHealth and Home Monitoring - 6th Edition 7mHealth and Home Monitoring - 6th Edition 8mHealth and Home Monitoring - 6th Edition 9mHealth and Home Monitoring - 6th Edition 10mHealth and Home Monitoring - 6th Edition 11
... Pharmaceuticals, Inc. (NYSE Amex: INO ), a ... against cancers and infectious diseases, has expanded its scientific ... in the fields of vaccines and cancer immunotherapeutics. Joining ... Professor of the Scripps Research Institute and founder of ...
... The Board of Directors of MSA (NYSE: MSA ... President of the company, responsible for Global Product Leadership.  Dr. ... 1, will assume the role of President of MSA International, ... his new role, Dr. Muschter will become a member of ...
Cached Medicine Technology:Inovio Pharmaceuticals Adds Two Medical Innovators to Its Scientific Advisory Board 2Inovio Pharmaceuticals Adds Two Medical Innovators to Its Scientific Advisory Board 3Inovio Pharmaceuticals Adds Two Medical Innovators to Its Scientific Advisory Board 4Inovio Pharmaceuticals Adds Two Medical Innovators to Its Scientific Advisory Board 5MSA Elects Dr. Thomas Muschter to Vice President 2
... Enzyme-linked immunosorbent assay method for ... autoantibodies to myeloperoxidase in human serum. ... can be used as an aid ... and other conditions associated with elevated ...
... of this Enzyme ImmunoAssay (EIA) is as ... immobilised on a 96 well microtiter plate. ... washing, the trapped molecule is covalently linked ... groups. After washing and denaturing treatment, Angiotensin ...
... determination of Ang II is ... the pharmacological effect and efficiency ... angiotensin converting enzyme inhibitors (ACE ... antagonists as well as for ...
Anti-RSV IgA Assay (ELISA)....
Medicine Products: