Navigation Links
Edison Pharmaceuticals announces initiation of EPI-743 Phase 2B Leigh Syndrome Clinical Trial
Date:11/13/2012

Mountain View, California; November 13, 2012. Edison Pharmaceuticals today announced the initiation of a phase 2B study entitled, "A Phase 2B Randomized, Placebo-Controlled, Double-Blind Clinical Trial of EPI-743 in Children with Leigh Syndrome." Four clinical trial sites have been selected in the United States: Lucile Packard Children's Hospital, Stanford University Medical Center Palo Alto, California; Akron Children's Hospital Akron, Ohio; Seattle Children's Hospital Seattle, Washington; and Texas Children's Hospital, Baylor University Houston, Texas.

The trial is a placebo-controlled study lasting six months, and then extending an additional six months, during which all subjects will receive EPI-743. Subjects must be between one and twelve years old, possess genetic confirmation of Leigh syndrome, and meet certain disease severity criteria. More information on the study specifics is available on ClinicalTrials.gov.

The primary endpoint of the clinical trial is the Newcastle Paediatric Mitochondrial Disease Scale. Secondary endpoints include neurologic, muscular, imaging, and biomarker indices. The study design was based on positive phase 2A data recently reported in the journal Molecular Genetics and Metabolism, "EPI-743 reverses the progression of the pediatric mitochondrial disease- genetically defined Leigh Syndrome" 107 (2012) 383-388.


'/>"/>

Contact: Lorraine Gilmore
Lgilmore@edisonpharma.com
650-641-9202
Edison Pharmaceuticals, Inc.
Source:Eurekalert

Page: 1

Related medicine news :

1. Environmentally friendly chemistry important for manufacturing pharmaceuticals
2. Scientists use sound waves to levitate liquids, improve pharmaceuticals
3. Plastic and Reconstructive Surgery Journal announces global expansion initiatives
4. NY-Presbyterian Hospital announces participation in trial for hard-to-treat hypertension
5. Northeasterns Barnett Institute announces formation of leading analytics company, BioAnalytix, LLC
6. JDRF announces winners of first phase of Agnes Varis Glucose-Responsive Insulin Challenge
7. CRF announces late breaking trials and first report investigations to be presented at TCT 2012
8. SfN announces winners of brain awareness video contest
9. COPD Foundation and BWH announces second phase of groundbreaking COPDGene project
10. NYU School of Medicine announces new clinical trial for ulcerative colitis
11. ASTRO announces 2012 fellows class
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/28/2017)... Manhattan New york (PRWEB) , ... April 28, ... ... is pleased to announce that Aditya Patel M.D. has joined the revolutionary endoscopic ... fellowship training and board certification in Interventional Pain Medicine. The patented, revolutionary eDiscSculpt ...
(Date:4/28/2017)... ... April 28, 2017 , ... People are starting to ... “Wearing a hearing aid doesn’t have the stigma it had when great-grandpa wore his ... of Greater Boston, in a NALA North American Speaker Series (NASS) segment. ...
(Date:4/28/2017)... (PRWEB) , ... April 28, 2017 , ... ... their work assisting the Brooke Grove Foundation implement a Microsoft Dynamics GP solution ... Solutions, a leading ERP expert that specializes in long-term care, Brooke Grove now ...
(Date:4/28/2017)... ... ... Christie Medical Holdings, Inc. , with its market-leading vein finder ... a leader in infusion therapy and pain management. , Intravenous (IV) therapy plays ... patients receiving a peripheral IV catheter as part of their treatment plan. Many hospitals ...
(Date:4/27/2017)... Minnesota (PRWEB) , ... April 27, 2017 , ... ... and her husband Dan Gasby the 2017 Public Leadership in Neurology Award (PLINA). ... Woodruff, retired professional athlete Tedy Bruschi, Vice President Walter Mondale, actor Michael J. ...
Breaking Medicine News(10 mins):
(Date:4/19/2017)... 2017  IRIDEX Corporation (Nasdaq: IRIX ) ... the first quarter 2017 after the close of trading ... will host a corresponding conference call beginning at 2:30 ... interested in listening to the conference call may do ... (703) 326-3030 for international callers, using conference ID: 92158987.  ...
(Date:4/19/2017)... 19, 2017 Global Prostate Cancer Therapeutics ... the prostate cancer therapeutics market analyzes the current ... prevalence of prostate cancer, launch of promising emerging ... of new drugs & therapeutic biological products, and ... to lesser side effects are some of the ...
(Date:4/19/2017)... PUNE, India , April 19, 2017 ... Type and Application, Forecast to 2022 report has covered and ... provides statistics and information on market size, shares and growth ... with major drivers, challenges and opportunities in the global market. ... Browse 152 Tables and ...
Breaking Medicine Technology: