Navigation Links
Early warning: PSA testing can predict advanced prostate cancer
Date:2/14/2008

Researchers who showed that a single prostate specific antigen (PSA) test at age 50 or under could predict the presence of prostate cancer up to 25 years later, (regardless of clinical significance) have now found that a single PSA can be used to predict advanced prostate cancer.

The findings, published in the online open access journal BMC Medicine, should help physicians identify which men would benefit from intensive screening.

More men die with prostate cancer than from it and in many cases the quality or length of their lives are not affected. However, advanced prostate cancer has serious consequences, including death. Researchers from Memorial Sloan-Kettering Cancer Center, New York and Lund University, Sweden set out to investigate the ability of a single PSA test to predict a diagnosis of advanced prostate cancer in later life. Advanced cancer was defined as one where the cancer had spread locally beyond the prostate or to other parts of the body at the time of diagnosis.

The team studied blood samples collected between 1974 and 1986 as part of a large population-based study of middle-aged men. The study cohort included 161 men who had been diagnosed with advanced prostate cancer by 1999 and men of a similar age who had not developed cancer by that time. The results showed that the total PSA level was an accurate predictor of advanced cancer diagnosis in later life. The majority (66%) of advanced cancers were seen in men whose PSA levels were in the top 20% (total PSA > 0.9 ng/ml). The median time from blood test to cancer diagnosis was 17 years.

The authors write: A single PSA test taken at or before age 50 is a very strong predictor of advanced prostate cancer diagnosed up to 25 years later. This suggests the possibility of using an early PSA test to risk stratify patients so that men at highest risk are the focus of the most intensive screening efforts.

Targeting screening could allow physicians to intervene when the cancer is at an early stage and still curable. It could also reduce overdiagnosis and unnecessary treatment in men with benign tumours.


'/>"/>

Contact: Charlotte Webber
press@biomedcentral.com
44-020-763-19980
BioMed Central
Source:Eurekalert

Related medicine news :

1. ReBuilder Medical Technologies, Inc. Announces 2007 Sales Nearly Doubled Sales in 2006
2. Cancer Drug Works Against MS in Early Trial
3. Yale test detects early stage ovarian cancer with 99 percent accuracy
4. New Survey Suggests Confusion, Lack of Awareness About Heart Failure Could Be Preventing Critical Early Detection and Treatment
5. JCI online early table of contents: Feb. 7, 2008
6. New study suggests link between environmental toxins and early onset puberty in girls
7. A Reminder to Parents: Early Dental Visits Essential to Childrens Health
8. Rheumatoid arthritis sends many into early retirement
9. Early detection critical in treating pediatric thyroid cancer
10. NFL Linemen Predisposed to Cardiovascular Disease; Early Detection is Key to Getting and Staying Healthy
11. Protein Linked With Poor Prognosis in Early-Stage Breast Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... LUIS OBISPO, Calif. (PRWEB) , ... October 13, 2017 , ... ... Alzheimer’s or dementia. However, many long-term care insurance companies have a waiver for care ... is the 90-day elimination period, when the family pays for care, is often waived, ...
(Date:10/13/2017)... ... 2017 , ... Talented host, actor Rob Lowe, is introducing ... new episode of "Success Files," which is an award-winning educational program broadcasted on ... subject in-depth with passion and integrity. , Sciatica occurs when the sciatic nerve ...
(Date:10/12/2017)... , ... October 12, 2017 , ... ... now treating sleep apnea using cutting-edge Oventus O2Vent technology. As many ... sleep disorder characterized by frequent cessation in breathing. Oral appliances can offer significant ...
(Date:10/12/2017)... ... , ... Asante, a nationally recognized health system in southern ... home health joint venture through an agreement, effective October 1, 2017, to create ... health company with Asante, delivering clinically integrated care, for the past eight years. ...
(Date:10/12/2017)... ... ... On Saturday, October 21, the Health & Wellness Center at Florida Hospital ... for the American Heart Association Heart Walk. Teams of up to 10 people can ... their treadmills moving for 5 hours. Treadmills will start at 7:00 p.m. on Saturday, ...
Breaking Medicine News(10 mins):
(Date:10/7/2017)... , Oct. 6, 2017   Provista, ... more than $100 billion in purchasing power, today announced ... and information. The Newsroom is the online ... industry trends, infographics, expert bios, news releases, slideshows and ... access to a wealth of resources at their fingertips, ...
(Date:10/4/2017)... 2017 OBP Medical , a ... devices, today announced regulatory approval from ... Agência Nacional de Vigilância Sanitária (ANVISA)) to market ... retractor with integrated LED light source and smoke ... exposure of a tissue pocket or cavity during ...
(Date:10/2/2017)... -- Halo Labs announces the European launch of their new low ... MIBio 2017 in Cambridge, U.K on October ... biopharmaceutical samples with unprecedented speed and sensitivity while using far less ... Imaging. ... analysis system ...
Breaking Medicine Technology: