Navigation Links
Early signs of heart disease in preadolescent children with type 1 diabetes
Date:2/14/2011

Cardiovascular disease is the leading cause of death in patients with diabetes. Patients with type 1diabetes have a 200 percent to 400 percent greater chance of developing cardiovascular disease than those without diabetes. Medical College of Wisconsin researchers at Children's Hospital of Wisconsin discovered the early signs of cardiovascular disease are likely to manifest before the onset of puberty in many children with diabetes.

Those findings are published in the February 2, 2011 online version of Diabetes Care and will be in the March 2011 issue of Diabetes Care.

Led by Dr. Ramin Alemzadeh, professor of pediatrics at the college and pediatric endocrinologist at Children's Hospital of Wisconsin, and Senior Clinician Scientist at Children's Hospital's Max McGee Juvenile Diabetes Research Center, the researchers studied 21 preadolescent children (avg. age 8.5 years) with type 1 diabetes, and compared that group to 15 healthy siblings. Investigators looked at flow-mediated dilatation (FMD), a gauge of the health of a major blood vessel of the upper arm artery, in both groups. FMD percentage (FMD%,) is a way to measure any stiffening of the blood vessels; stiffening blood vessels is an early precursor of cardiovascular disease.

Children who had high blood pressure, family history of high cholesterol or premature cardiovascular disease from other causes were excluded. Blood samples were collected from all participants to monitor cholesterol and sugar levels.

When tested, the blood vessels of children with type 1 diabetes had a lower FMD% change, which means their blood vessels were less expandable than the control group suggesting that higher circulating glucose results in increased rigidity of blood vessels independent of serum cholesterol levels. The patients with diabetes also had vascular inflammation, which is a known harbinger of future cardiovascular risk. Long-term studies are needed to evaluate the progression of those vascular changes through puberty and beyond.


'/>"/>

Contact: Maureen Mack
mmack@mcw.edu
414-955-4744
Medical College of Wisconsin
Source:Eurekalert

Related medicine news :

1. JCI online early table of contents: Feb. 14, 2011
2. Early Birth Risky, Even With Fully Developed Lungs: Study
3. Nearly 25% of Women With Early Ovarian Cancer Not Given Recommended Biopsies
4. Removing Many Lymph Nodes in Early Breast Cancer Not Always Needed: Study
5. Researchers predict nearly 1.3 million cancer deaths in Europe in 2011
6. Universal Flu Vaccine Shows Promise in Early Trial
7. Giving Baby Solid Foods Too Early Linked to Obesity Later
8. JCI online early table of contents: Feb. 7, 2011
9. Urine-sniffing dogs: Early detection of prostate cancer
10. Obesity Has Nearly Doubled Worldwide Since 1980: Report
11. Early infusion of donor T cells prevents graft versus host disease in blood cancer patients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/19/2017)... ... January 19, 2017 , ... ... has recently unveiled impressive transportable capabilities with their iMedHD2™ Portable Teleultrasound ... extension to RMT technology that delivers HD, dynamic, streaming ultrasound images and video ...
(Date:1/19/2017)... ... 19, 2017 , ... Dr. Andrew Lian-Jie Li ... trained Mohs and cosmetic surgeon. After extensive dermatology research training at the National ... in internal medicine at the Emory University and dermatology training at the University ...
(Date:1/19/2017)... Texas (PRWEB) , ... January 19, 2017 , ... Students ... GenCure Tissue Donation Awareness Scholarship competition., The winner will earn a $1,000 scholarship and ... The competition begins Feb. 1, and the deadline is May 31, with the winner ...
(Date:1/19/2017)... ... January 19, 2017 , ... Allegheny Health Network (AHN) officials today ... access to the Network’s programs and services in the greater Pittsburgh region. Starting January ... will be offered one for that same afternoon. , AHN is ...
(Date:1/19/2017)... ... 2017 , ... For the third year running, Noto Insurance ... surrounding area, is inaugurating a charity event to help raise funds for ... Gehrig's disease or motor neurone disease, is a deadly neurological disorder that affects ...
Breaking Medicine News(10 mins):
(Date:1/19/2017)... NEW YORK , Jan. 19, 2017 /PRNewswire/ ... reach USD 233.7 billion by 2025, according to ... The market is anticipated to be predominantly driven ... companies, resulting into the large-scale production of new ... widen the influx of drugs at an unprecedented ...
(Date:1/19/2017)... -- Report Details ... Alzheimer,s Disease Therapeutics and Diagnostics ... new study reveals trends, R&D progress, and predicted revenues ... Alzheimer,s disease therapeutics and diagnostics market. Our new report ... How is the Alzheimer,s disease therapeutics and diagnostics market ...
(Date:1/19/2017)... According to a study conducted by Persistence Market Research ... CAGR of 6.5% during the forecast period 2016-2024. According to the ... the leading market for cryotherapy globally during the forecast period  ... Highlights from the Report  ... adequate supply of gas in order to provide smoother maintenance services ...
Breaking Medicine Technology: