Navigation Links
Early menopause predicts a milder form of rheumatoid arthritis
Date:6/8/2012

Berlin, Germany, June 8 2012 : A new study presented today at EULAR 2012, the Annual Congress of the European League Against Rheumatism, shows that early menopause predicts a milder form of rheumatoid arthritis (RA). New insights on factors influencing RA are good news for sufferers of the chronic inflammatory disease that currently affects over 2 million women in Europe. 1,2

The study, based on 134 incident RA cases, found that patients aged over 45 years with a history of early menopause were 50% less likely to develop severe RA (16% versus 35%) and more likely to develop a mild/moderate rheumatoid factor (RF) negative phenotype (58% versus 20%). There was no major difference in RA severity depending on oral contraceptive use or history of breast feeding. This study highlights that hormonal changes may influence pathways that are distinct from those leading to severe, progressive disease.

Dr. Mitra Pikwer from Skne University Hospital, Sweden, and lead study author commented: "We already know that hormonal factors may influence the risk of RA, but this is the first study we know of that investigates the impact of menopausal age on the severity of RA. This is an important breakthrough, both in helping us understand the impact that hormones may have on the development of this disease and potentially also in helping us predict the long-term prognosis for our patients."

The study identified patients who answered a questionnaire in a community based health survey (conducted between 1991 and 1996) and later developed RA. Information on hormonal predictors including breastfeeding history, history of oral contraceptive use and menopausal age (early menopause ≤45 years or normal/late menopause > 45 years) was obtained via the questionnaire. By a structured review of the patients medical records, relevant information such as use of disease modifying anti-rheumatic drugs (DMARDs) including biological treatment, radiographic erosions, rheumatoid factor (RF) status as well as Health Assessment Questionnaire (HAQ*) data was collected. These variables were added to the SPSS TwoStep Cluster Analysis in order to reveal natural groupings of RA severity.


'/>"/>

Contact: Candice Debleu
eularpressoffice@cohnwolfe.com
44-789-438-6425
European League Against Rheumatism
Source:Eurekalert

Related medicine news :

1. 9 in 10 Blacks With High Blood Pressure Have Early Heart Disease
2. Study Spots Early Warning Signal for Sudden Cardiac Death
3. A systems approach to preventing obesity in early life
4. Research With Dogs Points to Early Test for Arthritis
5. Early Study Hints at Link Between Certain Sunscreens, Endometriosis
6. Early biomarker for pancreatic cancer identified
7. Clemson professor awarded nearly $600,000 4-year grant to study language of plants
8. Back Pain Therapy Often Yields Early Benefits: Study
9. Revenue-driven surgery drives patients home too early
10. Highly targeted irradiation as good as whole breast radiotherapy in early stage cancer
11. Southeast program to fight diabetes awarded nearly $10 million by HHS
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/24/2017)... Tampa, Fla. (PRWEB) , ... June 24, 2017 ... ... Fla., is now offering genetic testing for medications in select Florida and Texas ... of pharmacogenomics. , This new application of genetic testing recognizes the role ...
(Date:6/23/2017)... ... June 23, 2017 , ... The Rhode Island ... Care Management Alerts and Dashboards, an innovative new service enabling healthcare providers to ... Care Management Alerts and Dashboards provide near real-time data about patients admitted to ...
(Date:6/23/2017)... ... June 23, 2017 , ... The Military Officers Association of America (MOAA) announced ... Veterans Affairs, retired Marine Col. Thomas G. Bowman. , Bowman currently serves as the ... an intimacy with the issues and challenges veterans face with the VA. Following a ...
(Date:6/23/2017)... (PRWEB) , ... June 23, 2017 , ... The Aesthetic ... facelift . Dr. Talei has come up with a proprietary technique that he calls ... lifts tissues that have dropped. For all ages, patients can expect to look refreshed, ...
(Date:6/23/2017)... Santa Monica, CA (PRWEB) , ... June 23, 2017 , ... ... PureLife as the endorsed amalgam separator supplier for CDA members. As part of the ... a reduced price of $99, saving more than $400 off the retail value. This ...
Breaking Medicine News(10 mins):
(Date:6/9/2017)... ALTO, Calif. , June 9, 2017 ... device company focused on the design, manufacture, sale and ... the market on the progress of its commercial roll-out ... is now available in more than one hundred (100) ... AeroForm offers a needle-free alternative for ...
(Date:6/7/2017)... , June 7, 2017 Endo International ... June 7, 2017, the Hon. Joseph R. Goodwin ... of West Virginia , entered a ... Inc. Pelvic Repair System Products Liability Litigation (the "MDL") ... MDL cases to provide expert disclosures on specific causation ...
(Date:6/3/2017)... -- Eli Lilly and Company (NYSE: LLY ... 3 MONARCH 2 study showed that abemaciclib, a ... with fulvestrant, significantly improved progression-free survival (PFS) compared ... hormone-receptor-positive (HR+), human epidermal growth factor receptor 2-negative ... progressed after endocrine therapy (median PFS, 16.4 vs. ...
Breaking Medicine Technology: