Navigation Links
Early menopause can result in earlier onset dementia
Date:1/27/2010

Women experiencing an early onset of menopause could develop dementia at a younger age. Research by Tonnie Coppus of Erasmus MC has indicated this. She studied women with Down Syndrome, who are known to have an early onset of menopause. The results of her research can be translated to apply to the general population. Her results will be published in the Journal of Alzheimer Disease today.

Women with Down Syndrome have an earlier onset of menopause compared to women in the general population, 44 years of age and 52 years of age, respectively. Coppus' findings show a strong relationship between the age of menopause onset and the age at which dementia is diagnosed. Coppus: "Women with Down Syndrome with an early onset of menopause also appear to suffer from dementia at an early age. In addition, my study shows that these women also die younger."

Alzheimer's disease is the major cause of illness and death among people with Down Syndrome. The Epidemiology department of Erasmus MC has been studying more than 500 people with Down Syndrome, above the age of 45, since 2000. In particular, the factors affecting the onset of dementia and death are studied. The health development found within this group is in fact an accelerated version of the developments found in the general population. The research results can therefore be translated to similar results for the general population.

A first step in the development of Alzheimer is the build up of so-called amyloid in the brain. The deposition of this amyloid occurs under influence of a certain gene, higher levels of which are found in people with Down Syndrome. Down Syndrome is a chromosomal disorder in which there are three copies of chromosome 21. This chromosome has various genes that play a role in neurological diseases. The most important of these is the gene that is responsible for the production of the protein amyloid. Coppus: "Studying the various factors that influence the development of Alzheimer's disease among people with Down Syndrome also improves our understanding of the role of amyloid in the development of Alzheimer's disease within the general population."

As it appears, not only can a relationship with the age of onset of dementia be determined but also a relationship between early onset of menopause and dying young. Coppus: "As dementia itself also leads to a reduced life expectancy, I made calculations in which I corrected the results of the effect of dementia on death. Despite this, the relationship between early menopause onset and dying young remains. The research results provide substantial information on the relationship between menopause and dementia and the relationship between menopause and death."


'/>"/>

Contact: Ceciel van Hemel
c.vanhemel@erasmusmc.nl
31-010-703-5285
IOS Press
Source:Eurekalert

Related medicine news :

1. New Test Might Smell Early Stage Lung Cancer
2. Early EKG Seems to Improve Odds After Heart Attack
3. Mayo Clinic and IBM Advance Early Detection of Brain Aneurysms
4. Ronald McDonald House Charities(R) (RMHC(R)) Awards Nearly $3 Million to Non-Profit Organizations
5. Mayo Clinic and IBM advance early detection of brain aneurysms
6. Ultrasound plus proteomic blood analyses may help physicians diagnose early-stage ovarian cancer
7. Nearly 7,500 RNs Ready to Deploy to Haiti
8. PRA International Rolls out Client Access to Oracle(R) RDC for Early Phase Studies
9. Might not be a tomorrow: Youth anticipate early death
10. Loss of Smell Could Be Early Sign of Alzheimers
11. Nearly 50,000 Vaccinated at 2-Day H1N1 Clinics; Pennsylvania Department of Health Continues Vaccination Efforts
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/28/2017)... (PRWEB) , ... June 28, 2017 , ... Eating disorders ... that every 62 minutes, at least one person dies as a direct result from ... greater need exists for qualified treatment providers. The iaedp Foundation meets this challenge by ...
(Date:6/28/2017)... ... 28, 2017 , ... American Farmer proudly announces the participation of Pure Line ... series, scheduled to broadcast fourth quarter 2017. American Farmer airs Tuesdays at 8:30aET on ... garden pea seed. As demand grew, the small company located in Moscow, Idaho extended ...
(Date:6/28/2017)... MT (PRWEB) , ... June 28, 2017 , ... ... provides insurance management and financial planning assistance to clients in southern Montana, is ... programs offered by Zoo Montana. , The outreach programs offered by Zoo Montana ...
(Date:6/28/2017)... Cincinnati, OH (PRWEB) , ... June 28, 2017 ... ... and financial consulting firm servicing communities throughout the greater Cincinnati metropolitan area, is ... help provide temporary lodgings for families with children receiving treatment in nearby hospitals. ...
(Date:6/27/2017)... ... June 27, 2017 , ... DrugDev understands that ... they can trust the sponsor to pay them correctly and on time. As the ... establish payment strategies that encourage sites to work on their studies. , At a ...
Breaking Medicine News(10 mins):
(Date:6/7/2017)... -- Endo International plc (NASDAQ: ENDP ) ... Joseph R. Goodwin , U.S. District Court Judge for ... , entered a case management order in MDL 2325, ... Litigation (the "MDL") that includes a provision requiring plaintiffs ... on specific causation within one hundred twenty (120) days ...
(Date:6/5/2017)... , June 5, 2017 Kohll,s Pharmacy & Homecare is ... the United States . The Raizer is a ... fallen person up to an almost-standing position within ... operated by one assistant and does not require ... enough that a child can operate it, and ...
(Date:5/30/2017)... DarioHealth Corp. (NASDAQ: DRIO), a leading global digital health ... it will be presenting at the 7th annual LD Micro Invitational ... Raphael , CEO, of DarioHealth will be giving the presentation and ... June 6th & 7th, 2017 at the Luxe Sunset Bel Air ... space. About LD Micro LD ...
Breaking Medicine Technology: