Navigation Links
Early menopause can result in earlier onset dementia
Date:1/27/2010

Women experiencing an early onset of menopause could develop dementia at a younger age. Research by Tonnie Coppus of Erasmus MC has indicated this. She studied women with Down Syndrome, who are known to have an early onset of menopause. The results of her research can be translated to apply to the general population. Her results will be published in the Journal of Alzheimer Disease today.

Women with Down Syndrome have an earlier onset of menopause compared to women in the general population, 44 years of age and 52 years of age, respectively. Coppus' findings show a strong relationship between the age of menopause onset and the age at which dementia is diagnosed. Coppus: "Women with Down Syndrome with an early onset of menopause also appear to suffer from dementia at an early age. In addition, my study shows that these women also die younger."

Alzheimer's disease is the major cause of illness and death among people with Down Syndrome. The Epidemiology department of Erasmus MC has been studying more than 500 people with Down Syndrome, above the age of 45, since 2000. In particular, the factors affecting the onset of dementia and death are studied. The health development found within this group is in fact an accelerated version of the developments found in the general population. The research results can therefore be translated to similar results for the general population.

A first step in the development of Alzheimer is the build up of so-called amyloid in the brain. The deposition of this amyloid occurs under influence of a certain gene, higher levels of which are found in people with Down Syndrome. Down Syndrome is a chromosomal disorder in which there are three copies of chromosome 21. This chromosome has various genes that play a role in neurological diseases. The most important of these is the gene that is responsible for the production of the protein amyloid. Coppus: "Studying the various factors that influence the development of Alzheimer's disease among people with Down Syndrome also improves our understanding of the role of amyloid in the development of Alzheimer's disease within the general population."

As it appears, not only can a relationship with the age of onset of dementia be determined but also a relationship between early onset of menopause and dying young. Coppus: "As dementia itself also leads to a reduced life expectancy, I made calculations in which I corrected the results of the effect of dementia on death. Despite this, the relationship between early menopause onset and dying young remains. The research results provide substantial information on the relationship between menopause and dementia and the relationship between menopause and death."


'/>"/>

Contact: Ceciel van Hemel
c.vanhemel@erasmusmc.nl
31-010-703-5285
IOS Press
Source:Eurekalert

Related medicine news :

1. New Test Might Smell Early Stage Lung Cancer
2. Early EKG Seems to Improve Odds After Heart Attack
3. Mayo Clinic and IBM Advance Early Detection of Brain Aneurysms
4. Ronald McDonald House Charities(R) (RMHC(R)) Awards Nearly $3 Million to Non-Profit Organizations
5. Mayo Clinic and IBM advance early detection of brain aneurysms
6. Ultrasound plus proteomic blood analyses may help physicians diagnose early-stage ovarian cancer
7. Nearly 7,500 RNs Ready to Deploy to Haiti
8. PRA International Rolls out Client Access to Oracle(R) RDC for Early Phase Studies
9. Might not be a tomorrow: Youth anticipate early death
10. Loss of Smell Could Be Early Sign of Alzheimers
11. Nearly 50,000 Vaccinated at 2-Day H1N1 Clinics; Pennsylvania Department of Health Continues Vaccination Efforts
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/8/2016)... ... December 08, 2016 , ... Premier Fitness Camp (PFC) and ... the ultimate weight loss and wellness program, at their world headquarters of Omni La ... immediate and long-term results to anyone seeking weight loss, personal development, a healthy lifestyle, ...
(Date:12/8/2016)... ... December 08, 2016 , ... ... continuity to its innovative Unified Instance Manager architecture, meeting the needs of ... new version optimizes the unattended auto-dialing system without agents, Presence Robodialer, provides ...
(Date:12/8/2016)... ... 08, 2016 , ... STATEN ISLAND, N.Y., Nov. 24, 2016 ... the highest standards of trauma, maternity, cancer and chronic obstructive pulmonary disease (COPD) ... Dr. Daniel Messina. , Among the recognitions, the American College of Surgeons' (ACS) ...
(Date:12/8/2016)... ... December 08, 2016 , ... California Senate Bill (SB) 863, signed into law ... in 2013 and 2014, according to CompScope™ Medical Benchmarks for California, 17th Edition ... to the study, medical payments per claim in California decreased 4 percent in 2013 ...
(Date:12/8/2016)... ... December 08, 2016 , ... ... Care Act. Dr. Botelho advocates for the mass media launching of story movements ... ongoing opportunities to share their unfortunate experiences; such a movement can generate the ...
Breaking Medicine News(10 mins):
(Date:12/8/2016)... , Dec. 8, 2016 Henry Schein, Inc. (Nasdaq: ... care products and services to office-based dental, animal health and ... equity investment in Marrodent, one of Poland,s ... $32 million. This transaction was announced on August 30, 2016. ... Poland since 2014, and Marrodent marks ...
(Date:12/8/2016)... 2016 Research and Markets has announced the addition ... to their offering. ... The report provides separate comprehensive analytics for ... and Rest of World. Annual estimates and forecasts are ... is provided for these markets. Market data and analytics are derived from ...
(Date:12/7/2016)... -- "Lantus (Insulin Glargine) Biosimilar Clinical Trial & Opportunity Insight" report by ... drug in clinical pipeline. Currently 5 biosimilar version of Lantus are commercially ... Kenya , Czech Republic , ... , Slovakia , United Kingdom ... patent on Lantus expired in 2014. Lantus is the brand name ...
Breaking Medicine Technology: