Navigation Links
Early menopause can result in earlier onset dementia

Women experiencing an early onset of menopause could develop dementia at a younger age. Research by Tonnie Coppus of Erasmus MC has indicated this. She studied women with Down Syndrome, who are known to have an early onset of menopause. The results of her research can be translated to apply to the general population. Her results will be published in the Journal of Alzheimer Disease today.

Women with Down Syndrome have an earlier onset of menopause compared to women in the general population, 44 years of age and 52 years of age, respectively. Coppus' findings show a strong relationship between the age of menopause onset and the age at which dementia is diagnosed. Coppus: "Women with Down Syndrome with an early onset of menopause also appear to suffer from dementia at an early age. In addition, my study shows that these women also die younger."

Alzheimer's disease is the major cause of illness and death among people with Down Syndrome. The Epidemiology department of Erasmus MC has been studying more than 500 people with Down Syndrome, above the age of 45, since 2000. In particular, the factors affecting the onset of dementia and death are studied. The health development found within this group is in fact an accelerated version of the developments found in the general population. The research results can therefore be translated to similar results for the general population.

A first step in the development of Alzheimer is the build up of so-called amyloid in the brain. The deposition of this amyloid occurs under influence of a certain gene, higher levels of which are found in people with Down Syndrome. Down Syndrome is a chromosomal disorder in which there are three copies of chromosome 21. This chromosome has various genes that play a role in neurological diseases. The most important of these is the gene that is responsible for the production of the protein amyloid. Coppus: "Studying the various factors that influence the development of Alzheimer's disease among people with Down Syndrome also improves our understanding of the role of amyloid in the development of Alzheimer's disease within the general population."

As it appears, not only can a relationship with the age of onset of dementia be determined but also a relationship between early onset of menopause and dying young. Coppus: "As dementia itself also leads to a reduced life expectancy, I made calculations in which I corrected the results of the effect of dementia on death. Despite this, the relationship between early menopause onset and dying young remains. The research results provide substantial information on the relationship between menopause and dementia and the relationship between menopause and death."


Contact: Ceciel van Hemel
IOS Press

Related medicine news :

1. New Test Might Smell Early Stage Lung Cancer
2. Early EKG Seems to Improve Odds After Heart Attack
3. Mayo Clinic and IBM Advance Early Detection of Brain Aneurysms
4. Ronald McDonald House Charities(R) (RMHC(R)) Awards Nearly $3 Million to Non-Profit Organizations
5. Mayo Clinic and IBM advance early detection of brain aneurysms
6. Ultrasound plus proteomic blood analyses may help physicians diagnose early-stage ovarian cancer
7. Nearly 7,500 RNs Ready to Deploy to Haiti
8. PRA International Rolls out Client Access to Oracle(R) RDC for Early Phase Studies
9. Might not be a tomorrow: Youth anticipate early death
10. Loss of Smell Could Be Early Sign of Alzheimers
11. Nearly 50,000 Vaccinated at 2-Day H1N1 Clinics; Pennsylvania Department of Health Continues Vaccination Efforts
Post Your Comments:
(Date:10/12/2017)... ... ... Asante, a nationally recognized health system in southern Oregon, ... health joint venture through an agreement, effective October 1, 2017, to create AccentCare ... company with Asante, delivering clinically integrated care, for the past eight years. This ...
(Date:10/12/2017)... ... October 12, 2017 , ... Dr. Parsa ... contributed a medical article to the newly revamped Cosmetic Town journal ... the hair transplant procedure known as Follicular Unit Extraction (FUE). , ...
(Date:10/12/2017)... ... 2017 , ... Leading pediatric oncology experts at Children’s National Health System ... Congress of the International Society of Paediatric Oncology (SIOP) Oct. 12-15. Chaired by ... and Blood Disorders at Children’s National, and Stephen P. Hunger, M.D., Chief of ...
(Date:10/12/2017)... GRAND RAPIDS, Mich. (PRWEB) , ... October 12, ... ... OnSite Wellness, has been named one of Michigan’s 2017 Best and Brightest in ... Best and Brightest in Wellness® awards program on Friday, Oct. 20 from 7:30 ...
(Date:10/12/2017)... ... , ... In the United States, single-family home owners pay ... York, New Jersey, Massachusetts, Texas, Virginia, Connecticut, and California—the average is $7,000 a ... rates, which contributes to the relatively lower cost of living in places like ...
Breaking Medicine News(10 mins):
(Date:10/2/2017)... 2, 2017 Halo Labs announces the European launch of ... the HORIZON at MIBio 2017 in Cambridge, U.K ... particulate matter in biopharmaceutical samples with unprecedented speed and sensitivity while ... technique Backgrounded Membrane Imaging. ... HORIZON subvisible particle analysis system ...
(Date:9/28/2017)... 2017 Cohen Veterans Bioscience and Early Signal ... wearable and home sensors for real-time monitoring of patients ... a nonprofit organization focused on disruptive health solutions for ... analytical system to record and integrate behavioral, cognitive, physiological ... ...
(Date:9/25/2017)... AMSTERDAM , Sept. 25, 2017   ... Trial Master File solutions, today—from the IQPC Trial ... Amsterdam , NL)—announced that EastHORN Clinical Services ... its clinical programs and TMF management. EastHORN, a ... Montrium,s eTMF platform to increase transparency to enable ...
Breaking Medicine Technology: