Navigation Links
Early indications of Parkinson's disease revealed in dream sleep
Date:3/28/2011

During a large-scale study of the socioeconomic costs of this neurodegenerative disease, Danish researchers, some from the University of Copenhagen, discovered that very early symptoms of Parkinson's disease may be revealed in dream or REM sleep.

Parkinson's disease is a brain disease best known for the trembling it causes. It is an incurable, chronic disease and gradually affects the muscles and mental capacity, seriously afflicting the lives if the patient and his or her immediate relatives.

"In the study we saw that eight years before diagnosis, Parkinson's sufferers exhibited work and health indications that something was wrong," says Poul Jennum, professor of clinical neurophysiology at the Center for Healthy Ageing, University of Copenhagen, and the Sleep Centre at Glostrup Hospital.

Among the very early symptoms is the sleep disorder RBD, or REM sleep behaviour disorder. REM is a particular stage of sleep in which we dream, and our eyes flicker rapidly behind our eyelids, hence the term REM, or Rapid Eye Movement. To prevent us from actually acting out our dreams the body usually shuts down our muscle movement during REM sleep, but in RBD it is still active, and REM sleepers with RBD display a range of behaviours from simple arm and leg spasms to kicking, shouting, seizing or jumping out of bed.

"In some cases their behaviour may be violent and result in injuries to the patients or their partners," Professor Jennum explains.

"Our hypothesis is that the very earliest stages of Parkinson's disease show up as various other diseases such as RBD," Jennum says.

In recent years, great advances have been made in the treatment of Parkinson's disease, but we still do not have therapies to mitigate the later symptoms, costs and increased mortality of the disease.

"This may become possible if we are able to intervene earlier, and if we are able to find clear indications of Parkinson's disease eight years sooner than we are now, this may give us an important tool. The question is of course whether we can actually say that RBD is always a very early marker for Parkinson's disease. That is what we are now investigating at the Sleep Centre at Glostrup Hospital," says Jennum.

Not surprisingly the study showed that Parkinson's sufferers are more often in contact with all sections of the health service, more often unemployed, more often on benefits, and on average cost the health service DKK 50,000 a year more than healthy control subjects.

For the study, researchers used the National Patient Register to identify all the patients diagnosed with Parkinson's disease between 1997 and 2007. 13,700 patients were compared to 53,600 healthy patients of the same sex, social class, educational background etc.

The study was carried out by researchers from the Center for Healthy Ageing, the Danish Center for Sleep Medicine, University of Copenhagen, Glostrup Hospital, Bispebjerg Hospital and the Danish Institute of Health Research, and was published in the Journal of Neurology, February 2011.


'/>"/>

Contact: Professor Poul Jennum
POJE@glo.regionh.dk
01-145-402-57495
University of Copenhagen
Source:Eurekalert

Related medicine news :

1. Teens Who Smoke Early Often Try Pot Later, Study Finds
2. Pancreatic Cancer Action Network and AACR award research grants totaling nearly $3 million
3. JCI online early table of contents: March 23, 2011
4. Exposure to chemicals in environment associated with onset of early menopause
5. Poor Diet Linked to Early Signs of Heart Risks in Obese Kids
6. Drinking Behavior May Be Tied to Early Alcohol Use
7. Detection of early gastric cancer using hydro-stomach CT
8. JCI online early table of contents: March 14, 2011
9. Early success of anti-HIV preventive oral drug regimen is promising, but questions remain
10. Simple blood test detects early emphysema in smokers before symptoms appear
11. CWRU researcher sends message to postmenopausal women: Increase yearly dental checkups
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/16/2017)... Maryland (PRWEB) , ... January 16, 2017 , ... ... Thibodeau has been appointed Chief Executive Officer of the medical device company, effective ... Vixiar Chairman Robert Storey. “Kevin has a strong track record in medical ...
(Date:1/15/2017)... ... January 15, 2017 , ... Whole Health Supply, LLC is announcing the release of an ... new avenues for purchase. , The 2017 edition has wide jaws that will accommodate ... older boomers as well as diabetics. This handle is reinforced for extra strength when pressing ...
(Date:1/15/2017)... ... January 14, 2017 , ... Wondering where to go ... delivered straight to your door for a romantic, lobster feast in the comfort of ... for Valentine's Day. The dinners will be featured until February 15th, 2017. , ...
(Date:1/14/2017)... , ... January 13, 2017 , ... ... and Soul, incorporating a magnesium-rich Mediterranean diet may lower the risk of type ... Lounge notes that the many health and wellness benefits linked to a Mediterranean ...
(Date:1/13/2017)... ... ... The 18th European Congress: Perspectives in Lung Cancer will be held in ... is expertly designed to meet the educational needs of European oncology clinicians and researchers ... Dr. Giorgio V. Scagliotti, Professor of Oncology at the University of Torino, and organized ...
Breaking Medicine News(10 mins):
(Date:1/16/2017)... PUNE, India , January 16, 2017 ... titled, "Vital Signs Monitoring Devices Market by Type and End ... the global vital signs monitoring devices market size was worth ... million by 2022, growing at a CAGR of 5.8% from ... the leading regional market in global vital signs monitoring devices ...
(Date:1/16/2017)... and PUNE, India , January ... new report published by Allied Market Research, titled, "Sterilization ... Analysis and Industry Forecast, 2014-2022," the global sterilization technologies ... from $5,768 million in 2015, growing at a CAGR ... gas sterilization segment dominated the market in 2015, with ...
(Date:1/16/2017)... PORTLAND, Oregon and PUNE, India , January 16, ... Market Research, titled, "Antioxidants Market by Type - Global Opportunity Analysis and Industry ... and is expected to reach $4,531 million by 2022, registering a CAGR of ... accounted for more than one-third share of the global volume in 2015. ... ...
Breaking Medicine Technology: