Navigation Links
Early exposure to certain bacteria may protect toddlers from wheezing
Date:6/6/2014

WHAT:

Research funded by the National Institutes of Health (NIH) suggests that exposure to specific combinations of allergens and bacteria within the first year of life may protect children from wheezing and allergic disease. These observations come from the Urban Environment and Childhood Asthma (URECA) study, which aims to identify factors responsible for asthma development in children from inner-city settings, where the disease is more prevalent and severe. Since 2005, the URECA study has enrolled 560 children from four citiesBaltimore, Boston, New York and St. Louis. The children all have at least one parent with asthma or allergies, placing them at high risk for developing asthma. The study is following the children from birth, and the current publication evaluates the group through three years of age.

During early life, recurrent wheezing and sensitivity to common allergens are risk factors for developing asthma. In the current study, the researchers measured the frequency of wheezing episodes and levels of exposure to five common inner-city allergenscat, cockroach, dog, dust mite and mouse. Surprisingly, they found that exposure to cockroach, mouse and cat during the first year of life was associated with a lower risk of recurrent wheezing by age three.

A smaller study within the URECA cohort tested whether bacteria, measured in house dust, influence asthma risk. Researchers sorted 104 children into four groups: no wheezing or sensitivity to allergens, wheezing only, sensitivity to allergens only, or both wheezing and sensitivity to allergens. They found that children with no wheezing or sensitivity to allergens at age three were more likely to have encountered high levels of allergens and a greater variety of bacteria, particularly those belonging to the Bacteriodes and Firmicutes groups, during their first year of life. These observations support the emerging concept that early-life exposure to high bacterial diversity may protect kids from developing allergies. Most importantly, the findings show that this protection is even stronger when children also encounter high allergen levels during this time.

The URECA study, funded by NIH's National Institute of Allergy and Infectious Diseases through its Inner-City Asthma Consortium, is no longer recruiting, but more information is available at ClinicalTrials.gov using the identifier NCT00114881. Additional funding was provided by the NIH's National Center for Advancing Translational Sciences. The research was conducted by investigators from several institutions, including the University of Wisconsin-Madison; the University of California, San Francisco; and Johns Hopkins University.


'/>"/>

Contact: Linda Huynh
linda.huynh@nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases
Source:Eurekalert  

Related medicine news :

1. Endocrine Society honors 2014 Early Investigators, FLARE Internship Award winners
2. Early palliative support services help those caring for patients with advanced cancer
3. Early steps toward personalized fitness: Interval training may benefit men more than women
4. New report estimates nearly 19 million cancer survivors in the US by 2024
5. Genetic profile predicts which bladder cancer patients will benefit from early chemotherapy
6. Having children is contagious among high school friends during early adulthood
7. MRI catches breast cancer early in at-risk survivors of childhood Hodgkin lymphoma
8. New drug for non-Hodgkin lymphoma and chronic lymphocytic leukemia passes early test
9. Bioethics commission plays early role in BRAIN Initiative
10. Early menopause ups heart failure risk, especially for smokers
11. Evolutionary biologists glimpse early stages of Y-chromosome degeneration
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Early exposure to certain bacteria may protect toddlers from wheezing
(Date:2/8/2016)... ... February 08, 2016 , ... GrassrootsHealth published ... rate of type 2 diabetes in the GrassrootsHealth cohort with substantially higher vitamin ... a change in public health,” states Carole Baggerly, Director of GrassrootsHealth, “the safety ...
(Date:2/8/2016)... Overland Park, KS (PRWEB) , ... February 08, 2016 , ... ... Oils, a leader in Mole removal products. , Moles are derived from a cluster ... can appear in all the wrong places and create a lifetime of embarrassment. Historically, ...
(Date:2/8/2016)... , ... February 08, 2016 , ... Guruji Mahendra Kumar ... 10th and 11th, 2016 in honor of his birthday on February 10th. During ... Mahendra Trivedi is known by over 250,000 people from over 40 different countries ...
(Date:2/8/2016)... ... February 08, 2016 , ... ... four states in the U.S. require dental technicians to be certified or obtain ... dental industry, NADL created the “What’s In Your Mouth?” campaign to inform dentists ...
(Date:2/7/2016)... ... February 07, 2016 , ... Women's Excellence staff, in ... Red Day. National Wear Red Day is the first Friday each February and ... and stroke cause 1 in 3 deaths among women each year – more than ...
Breaking Medicine News(10 mins):
(Date:2/8/2016)... -- Neurocrine Biosciences, Inc. (Nasdaq: NBIX ) announced today ... year-end 2015 results after the Nasdaq market closes on ... live conference call and webcast to discuss its financial ... 11, 2016 at 4:30 p.m. Eastern Time (1:30 p.m. ... http://www.neurocrine.com . --> Participants can access the ...
(Date:2/8/2016)... -- http://www.researchandmarkets.com/research/fqx6nz/global_skin ) has announced ... Equipment Market 2016-2020" report to their offering. ... announced the addition of the "Global Skin ... offering. --> Research and ... of the "Global Skin Protective Equipment Market ...
(Date:2/8/2016)... --  Intarcia Therapeutics, Inc. today announced the appointment ... newly created role of Vice President, Head of Global ... decades of leadership experience at leading pharmaceutical, biotechnology, and ... center. Most recently Dr. Yee served as VP, Head ... Medical Officer at AstraZeneca, where he led medical affairs ...
Breaking Medicine Technology: