Navigation Links
Early exposure to certain bacteria may protect toddlers from wheezing
Date:6/6/2014

WHAT:

Research funded by the National Institutes of Health (NIH) suggests that exposure to specific combinations of allergens and bacteria within the first year of life may protect children from wheezing and allergic disease. These observations come from the Urban Environment and Childhood Asthma (URECA) study, which aims to identify factors responsible for asthma development in children from inner-city settings, where the disease is more prevalent and severe. Since 2005, the URECA study has enrolled 560 children from four citiesBaltimore, Boston, New York and St. Louis. The children all have at least one parent with asthma or allergies, placing them at high risk for developing asthma. The study is following the children from birth, and the current publication evaluates the group through three years of age.

During early life, recurrent wheezing and sensitivity to common allergens are risk factors for developing asthma. In the current study, the researchers measured the frequency of wheezing episodes and levels of exposure to five common inner-city allergenscat, cockroach, dog, dust mite and mouse. Surprisingly, they found that exposure to cockroach, mouse and cat during the first year of life was associated with a lower risk of recurrent wheezing by age three.

A smaller study within the URECA cohort tested whether bacteria, measured in house dust, influence asthma risk. Researchers sorted 104 children into four groups: no wheezing or sensitivity to allergens, wheezing only, sensitivity to allergens only, or both wheezing and sensitivity to allergens. They found that children with no wheezing or sensitivity to allergens at age three were more likely to have encountered high levels of allergens and a greater variety of bacteria, particularly those belonging to the Bacteriodes and Firmicutes groups, during their first year of life. These observations support the emerging concept that early-life exposure to high bacterial diversity may protect kids from developing allergies. Most importantly, the findings show that this protection is even stronger when children also encounter high allergen levels during this time.

The URECA study, funded by NIH's National Institute of Allergy and Infectious Diseases through its Inner-City Asthma Consortium, is no longer recruiting, but more information is available at ClinicalTrials.gov using the identifier NCT00114881. Additional funding was provided by the NIH's National Center for Advancing Translational Sciences. The research was conducted by investigators from several institutions, including the University of Wisconsin-Madison; the University of California, San Francisco; and Johns Hopkins University.


'/>"/>

Contact: Linda Huynh
linda.huynh@nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases
Source:Eurekalert  

Related medicine news :

1. Endocrine Society honors 2014 Early Investigators, FLARE Internship Award winners
2. Early palliative support services help those caring for patients with advanced cancer
3. Early steps toward personalized fitness: Interval training may benefit men more than women
4. New report estimates nearly 19 million cancer survivors in the US by 2024
5. Genetic profile predicts which bladder cancer patients will benefit from early chemotherapy
6. Having children is contagious among high school friends during early adulthood
7. MRI catches breast cancer early in at-risk survivors of childhood Hodgkin lymphoma
8. New drug for non-Hodgkin lymphoma and chronic lymphocytic leukemia passes early test
9. Bioethics commission plays early role in BRAIN Initiative
10. Early menopause ups heart failure risk, especially for smokers
11. Evolutionary biologists glimpse early stages of Y-chromosome degeneration
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Early exposure to certain bacteria may protect toddlers from wheezing
(Date:6/27/2016)... , ... June 27, 2016 ... ... the patient payment industry today announced its strategic partnership with Connance, a ... workflows. , The two companies’ proven, proprietary technology combine to provide health ...
(Date:6/26/2016)... ... June 26, 2016 , ... Pixel Film Studios Released ProSlice Levels, a ... can give their videos a whole new perspective by using the title layers ... Film Studios. , ProSlice Levels contains over 30 Different presets to choose from. ...
(Date:6/25/2016)... ... June 25, 2016 , ... Austin residents seeking Mohs surgery services, can ... Surgery and to Dr. Russell Peckham for medical and surgical dermatology. , Dr. Dorsey ... cancer. The selective fellowship in Mohs Micrographic Surgery completed by Dr. Dorsey was under ...
(Date:6/25/2016)... Oklahoma (PRWEB) , ... June 25, 2016 , ... ... both athletes and non-athletes recover from injury. Recently, he has implemented orthobiologic procedures ... Oklahoma City area —Johnson is one of the first doctors to perform the ...
(Date:6/24/2016)... ... , ... June 19, 2016 is World Sickle Cell Observance Day. In an ... of holistic treatments, Serenity Recovery Center of Marne, Michigan, has issued a ... Cell Disease (SCD) is a disorder of the red blood cells, which can cause ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... Dehaier Medical Systems Ltd. (NASDAQ: ... and sells medical devices and wearable sleep respiratory products ... cooperation agreement with Hongyuan Supply Chain Management Co., Ltd. ... 20, 2016, to develop Dehaier,s new Internet medical technology ... will leverage Hongyuan Supply Chain,s sales platform to reach ...
(Date:6/24/2016)...   Pulmatrix, Inc ., (NASDAQ: PULM ... announced today that it was added to the Russell ... comprehensive set of U.S. and global equity indexes on ... milestone for Pulmatrix," said Chief Executive Officer Robert ... progress in developing drugs for crucial unmet medical needs, ...
(Date:6/23/2016)... June 23, 2016 Research and Markets ... Market - Forecast to 2022" report to their offering. ... method for the patients with kidney failure, it replaces the ... from the patient,s blood and thus the treatment helps to ... chloride in balance. Increasing number of ESRD ...
Breaking Medicine Technology: