Navigation Links
Early detection of lung cancer
Date:2/2/2011

This release is available in German.

Lung tumors are the number one cause of death among cancer patients, and one cancer in three is lung cancer. Each year, there are 50,000 new cases of the disease in Germany alone. The earlier a tumor can be detected, the greater the chance of healing the patient. But early detection is difficult. In its initial stages, the tumor-related complaints resemble chronic inflammatory reactions. To get a more complete diagnosis, the patient must undergo an X-ray examination or an bronchoscopy. The last procedure often involves irritation of the lung or removal of tissue samples and, as a result, it is particularly unpleasant for the patient undergoing the procedure. In recent years, scientists at the Fraunhofer Institute for Cell Therapy and Immunology IZI in Leipzig have teamed up with colleagues at the University Clinic of Leipzig to develop a procedure that can detect special protein biomarkers in exhaled air. The presence of biomarkers suggests the presence of tumor cells in the lung. In a project sponsored by the Federal Ministry of Education and Research (BMBF), the specialists want to work with partners in industry two medium-sized companies in the regional to produce a first prototype that can then be further developed into a diagnostic tool that can be used in practice.

"Since 2006, working with the working groups of Professor Hubert Wirtz and Professor Ulrich Sack of the University Clinic, we first identified various biomarkers that are particularly well-suited for the identification of lung-cancer cells," notes Dr. Jrg Lehmann, head of the Cell Engineering/GLP Unit at IZI. "The main difficulty lies in finding a reliable way to distinguish cancer from chronic inflammatory disease." The researchers have developed a laboratory method for reliably identifying biomarkers specific to lung cancer in special samples of exhaled air. To accomplish this, the patient must breathe into a piece of equipment for roughly 20 minutes. The exhaled breath condensate is then evaporated. Biomarkers are detected by means of special antibodies that recognize substances such as the protein VEGF. This protein is responsible for stimulating the growth of new blood vessels. This laboratory method is still too "elaborate and expensive" for normal everyday use, the scientist adds. "Working in our joint project, the goal for the next two years is to produce a prototype that will then be validated in a clinical-diagnostic study and further developed to the production stage," Lehmann says.

In their new testing platform, the scientists have actually applied two new developments: in addition to the method enlisting protein biomarkers to identify cancer cells, they also make use of the antibody specially developed for this procedure. This way, within just a few years, every physician investigating a suspicion of lung cancer can use the diagnostic platform right in his or her practice to test whether there really is a tumor and quickly initiate treatment.


'/>"/>

Contact: Joerg Lehmann
joerg.lehmann@izi.fraunhofer.de
49-341-355-361-205
Fraunhofer-Gesellschaft
Source:Eurekalert

Related medicine news :

1. Minnesota Department of Health Report: Nearly 6,000 Hospitalizations for COPD in 2007
2. Moms Lifestyle in Early Pregnancy Affects Babys Size
3. Early life stress may predict cardiovascular disease
4. MDS Announces Agreements to Divest MDS Pharma Services Early Stage Business
5. Alzheimers Association Applauds Social Security Administration for Adding Early-Onset Alzheimers to Its Compassionate Allowances Initiative
6. Alzheimers Foundation of America Applauds Social Security for Speeding Disability Benefits for Early-Onset Alzheimers Disease
7. JCI online early table of contents: Feb. 15, 2010
8. 29 Clear Channel stations Nationwide Raise Nearly $2.8 Million to Help Save the Lives of Kids Fighting Cancer and Other Deadly Diseases
9. Researchers find biomarkers in saliva for detection of early-stage pancreatic cancer
10. Early On, Hormone Therapy May Raise Womens Heart Risks
11. FriendsofWater.com Responds to the National Acadamy of Sciences Report that Millions of Americans Get Sick Yearly from Contaminated Water
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/26/2017)... ... February 26, 2017 , ... ODH, Inc.™ announced today it will ... the Sheraton Pentagon City Hotel in Arlington, VA. ODH’s director of medical strategy, Candace ... analytics to improve Medicaid population health management. , ODH will also have an exhibit ...
(Date:2/25/2017)... ... February 25, 2017 , ... FCPX users now have ... from Pixel Film Studios. With ProSharpen Color users have total control over sharpening amount, ... their color range. With color spectrum tools users can visually see the color range ...
(Date:2/24/2017)... ... February 24, 2017 , ... Only two months after the official release of ... in Cannes (France), XO Private has initiated a second print-run of its lavish luxury ... a metre across when open, weighs in at more than six kilos, retails at ...
(Date:2/24/2017)... ... ... Dr. Ronald E. Hawkins, vice president for academic affairs ... Bell, DO, MBA, HPF, FACOEP-dist., FACEP, as the new dean of Liberty ... to Liberty from the Ohio University Heritage College of Osteopathic Medicine (OU-HCOM), where ...
(Date:2/24/2017)... ... February 24, 2017 , ... With millions of ... critically important that we all are aware of our options and are empowered ... to announce the launch of its newest edition of "Vision and Hearing" in ...
Breaking Medicine News(10 mins):
(Date:2/24/2017)... CUPERTINO, Calif. , Feb. 24, 2017  In ... fourth quarter 2016 financial results press release, you are ... be broadcast live over the internet on Tuesday, March ... Pacific Time). A live audio webcast of ... at www.durect.com and clicking "Investor Relations."  If ...
(Date:2/24/2017)... Report analyzes the worldwide markets for Endodontic Supplies ... the US, Canada , Japan ... , Latin America , and Rest ... period 2015 through 2022. Also, a six-year historic analysis is ... from primary and secondary research. Company profiles are primarily based ...
(Date:2/24/2017)... NEW YORK , Feb. 23, 2017  This ... US$ Thousand by the following Products: ... analyzed in the report include Pharmaceuticals, and Agrochemicals. The ... Japan , Europe , ... provided for the period 2015 through 2022. Also, a ...
Breaking Medicine Technology: