Navigation Links
Early detection of MS treatment complication may improve survival
Date:3/10/2013

SAN DIEGO The drug natalizumab is effective for treating multiple sclerosis (MS), but it increases the risk of a rare but potentially fatal brain infection called progressive multifocal leukoencephalopathy (PML). A study released today that will be presented at the American Academy of Neurology's 65th Annual Meeting in San Diego, March 16 to 23, 2013, suggests that early detection of PML may help improve survival and disability levels.

The study examined 319 people with MS who were treated with natalizumab and diagnosed with PML. Because of the risk of PML, people taking natalizumab are monitored by their physicians for possible symptoms of the brain infection. The study compared people who had symptoms of PML at the time of diagnosis to people who had no symptoms of the infection, but who were diagnosed with the disease by brain scans and tests in the spinal fluid for the virus that causes the infection. The level of disability for the people in the study was assessed before the PML diagnosis, at the time of diagnosis, and again six months and one year after the diagnosis.

A total of 21 people had no PML symptoms at the time of their diagnosis, while 298 people had symptoms. The preliminary data from the study suggest that people who have no symptoms at diagnosis may have improved survival and less disability than those who had developed symptoms prior to their diagnosis, according to study author Tuan Dong-Si, MD, a medical director with Biogen Idec in Weston, MA.

At the time of PML diagnosis, those people with no symptoms had an average score of 67 on the Karnofsky Performance Scale, which measures disability, while those people with symptoms had a score of 54. A Karnofsky score of 70 indicates that the individual may be able to care for him or herself, but may be unable to carry on normal activities or do active work. A Karnofsky score of 50 indicates that a person may require considerable assistance and frequent medical c
'/>"/>

Contact: Rachel Seroka
rseroka@aan.com
612-928-6129
American Academy of Neurology
Source:Eurekalert

Page: 1 2

Related medicine news :

1. New Stool Test Might Aid in Early Detection of Colon Cancer
2. An Early Start for Your Child with Autism
3. Early Study Finds Some Promise for Lung Cancer Vaccine
4. Treat Rheumatoid Arthritis Early and Aggressively: Guidelines
5. JCI early table of contents for April 9, 2012
6. Eye Tremors May Aid Early Diagnosis of Parkinsons: Study
7. Nearly 1 in 4 grandparents store prescription medicines where children can easily find them
8. First contact: Early intervention key in diagnosis and treatment of serious mental illness
9. Brain Tumor Vaccine Shows Promise in Early Trial
10. Role of Screening, Monitoring in Early Kidney Disease Unclear
11. Detecting malaria early to save lives: New optical technique promises rapid and accurate diagnosis
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/17/2014)... Boston Children’s Museum and From the ... series, introducing young Museum visitors to musicians from ... national platform celebrating the stories, talents, and character ... musicians featured will also be showcased on NPR's ... fortunate to partner with the wonderful musicians of ...
(Date:9/17/2014)... 2014 Why are Asian Americans at higher risk ... prone to develop the disease at lower body weights? ... transition from traditional high-fiber, low-fat Asian diets to current ... of Asian heritage, says George King, M.D., Senior Vice ... and the senior author of the study. , A ...
(Date:9/17/2014)... Leading eco-friendly beauty brand , Lotus Moon, ... vegan and gluten-free Sugar Cane Fruit Mask. Their newest ... skincare testers were looking for. , “My goal ... that provided results, and I think I accomplished it,” ... Mask combines Willow bark (Salix Alba extract), a natural ...
(Date:9/17/2014)... The Delta Dental Community Care Foundation announced ... Oral Health Foundation: America’s ToothFairy (NCOHF) to support oral ... Health Zone Program® in California. , The Orange County ... of local constituent groups and stakeholders in a comprehensive ... and its devastating effects on local families. The support ...
(Date:9/17/2014)... Managing diabetes, quitting smoking, controlling high blood pressure, exercising ... for dementia -- even late in life, according to ... commissioned by Alzheimer,s Disease International, revealed that diabetes can ... study noted that obesity and an inactive lifestyle are ... blood pressure. The researchers suggested that dementia ...
Breaking Medicine News(10 mins):Health News:Boston Children's Museum Partners with From the Top to Offer Monthly Concert Series 2Health News:Boston Children's Museum Partners with From the Top to Offer Monthly Concert Series 3Health News:In Joslin trial, Asian Americans lower insulin resistance on traditional diet 2Health News:In Joslin trial, Asian Americans lower insulin resistance on traditional diet 3Health News:EcoBeauty Brand Lotus Moon Unveils New Gluten-Free Sugar Cane Fruit Mask 2Health News:Delta Dental Community Care Foundation Donation to America's ToothFairy Helps Deliver Critical Services 2Health News:Healthy Lifestyle Changes Linked to Reduced Risk for Dementia 2Health News:Healthy Lifestyle Changes Linked to Reduced Risk for Dementia 3
... scientists have developed a hormone-free contraceptive pill for men they ... tablet, developed by researched at King's College London, can be ... being able to impregnate a woman. However, his fertility would ... edition of Daily Mail. ,Contraceptive pills available in ...
... Jai Prakash Narayan Apex Trauma Center (JPNATC), which was conceived ... patients of road accidents. ,The All India ... sq meters, seven-storey hospital with 200 beds, including 16 ICU ... dry run on Monday by shifting 55 'not so critical ...
... unearthed clues,from studies on dragonflies, that may help in ... revealed that when dragonflies are infected with certain parasites ... similar to the Type -2 diabetes seen in humans. ... studies may hold the key to understanding the underlying ...
... the Department of Molecular, Cellular and Developmental Biology (MCDB) ... awarded// the prestigious 2006 E. B. Wilson Medal, ... scientific research in cell biology. ,The medal ... assembly, maintenance and function of fine, hair-like cell organelles, ...
... brain protein known to underlie a form of Parkinson's disease ... branching of neurons//, researchers have found. They have pinpointed the ... gene called LRRK2 and how it affects neurons, ultimately leading ... to the pathology of PD, and loss of connections among ...
... in 2002 to work in the National Health Service but was ... incurable brain disease, will now be// able to return to India ... ,Kaushik Chatterjee, a doctor from Kolkata, came to Britain in ... was appointed senior house officer in elderly care at Sunderland Royal ...
Cached Medicine News:Health News:Prestigious Wilson Award Goes To Yale Cell Biologist Joel Rosenbaum 2Health News:Prestigious Wilson Award Goes To Yale Cell Biologist Joel Rosenbaum 3Health News:Prestigious Wilson Award Goes To Yale Cell Biologist Joel Rosenbaum 4Health News:Prestigious Wilson Award Goes To Yale Cell Biologist Joel Rosenbaum 5Health News:Parkinson's Mutation Stunts Neurons 2Health News:Ailing Indian doctor in Britain to return to Kolkata 2
(Date:9/17/2014)...  Dr. Stephen Loyd , a recovering substance ... National Recovery Month, stars in a new television ad ... advocates were also joined by a Los ... her fiancée because of a preventable error in surgery ... of crack cocaine abuse. Proposition 46 would identify doctors ...
(Date:9/17/2014)... , Sept. 17, 2014 /PRNewswire-iReach/ -- ChemImage ... paper discussing improvements in the development of ... for both normal and diseased tissue that ... simplifies surgical procedures, lowers surgical costs and ... procedures. The clinical and ...
(Date:9/17/2014)... Calif. , Sept. 17, 2014 ... Prostate Vanguard, an awareness campaign to educate men about ... needle biopsies of the prostate. Annually, a million ... gland through the rectum. Multi-parametric MRI (MP-MRI) of the ... prostate cancer (CSPC). Men need to be fully ...
Breaking Medicine Technology:Doctor Recovering From 100-Pill-A-Day Addiction Stars In New Ad Supporting Prop 46; Appears At White House for National Recovery Month, Says Consumer Watchdog Campaign 2Doctor Recovering From 100-Pill-A-Day Addiction Stars In New Ad Supporting Prop 46; Appears At White House for National Recovery Month, Says Consumer Watchdog Campaign 3Patient Outcomes Improve When Molecular Chemical Imaging Technology Is Used to Aid Robotic Surgical Procedures, According to New White Paper 2Prostate Cancer Awareness Month - Stop Random Biopsies 2Prostate Cancer Awareness Month - Stop Random Biopsies 3
... 2 MedAvante, Inc., the leader in centralized evaluation of central nervous ... Service for trials assessing Alzheimer,s Disease. Its CQC Services are already in use ... in the United States , Europe , Asia , ... , , ...
... HARBIN, China , June 2 /PRNewswire-Asia-FirstCall/ ... a,developer, manufacturer and distributor of botanical products,bio-pharmaceuticals and traditional Chinese ... a conference call at 9:00 a.m. Eastern Time ... for the second quarter of its,fiscal year 2010, ended ...
Cached Medicine Technology:MedAvante Launches Service to Boost Reliability of Assessments to Reduce Risk of Failed Alzheimer's Disease Trials 2MedAvante Launches Service to Boost Reliability of Assessments to Reduce Risk of Failed Alzheimer's Disease Trials 3Renhuang Schedules Conference Call to Discuss FY 2010 Second Quarter Results 2Renhuang Schedules Conference Call to Discuss FY 2010 Second Quarter Results 3
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: