Navigation Links
Early Use of NSAIDs Might Prevent Alzheimer's
Date:11/10/2009

Study in mice finds anti-inflammatories don't help those with existing disease

TUESDAY, Nov. 10 (HealthDay News) -- Taking nonsteroidal anti-inflammatory drugs (NSAIDs) from a young age might prevent early signs of Alzheimer's disease, according to the results of a new study in mice.

Recent research suggests that the appearance of neuronal cell cycle events (CCEs) occurs early in the development of Alzheimer's. In the new study, U.S. researchers looking for triggers of neuronal CCEs found evidence that suggests that neuroinflammation plays a role in the development of Alzheimer's in mice.

Administration of the inflammatory molecule LPS triggered the early appearance of neuronal CCEs, the researchers found, and treatment with the NSAIDs ibuprofen or naproxen blocked the development of CCEs.

In older mice, treatment with NSAIDs prevented new neuronal CCEs but did not affect existing CCEs, the study authors noted.

The study, published online Nov. 9 in the Journal of Clinical Investigation, offers a potential explanation for findings in humans that long-term NSAID use protects against Alzheimer's but does not benefit people who already have mild to moderate Alzheimer's disease.

More information

The U.S. National Institute on Aging has more about Alzheimer's disease.



-- Robert Preidt



SOURCE: Journal of Clinical Investigation, news release, Nov. 9, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved

Page: 1

Related medicine news :

1. Early Relapse of MS May Mean Fewer Issues Later
2. Early Morning Colonoscopies May Find More Polyps
3. Approved lymphoma drug shows promise in early tests against bone cancer
4. Omnicare Pays Nearly $100 Million to Resolve Medicaid Fraud Charges: Second Omnicare Settlement With Chicago Whistleblower Pharmacist
5. Early-stage, HER2-positive breast cancer patients at increased risk of recurrence
6. Nearly half of all US children will use food stamps, says poverty expert at WUSTL
7. Syphilis survey reveals need for accurate testing for early infection
8. Karmanos Cancer Institute Immunology Researcher Obtains Nearly $1 Million National Institutes of Health Grant
9. Indiana Home Health Agency Pays Nearly $2 Million to Settle False Claims Act Allegations
10. Clearlycontacts.Ca Named as One of Bc's Top Employers
11. Skin cells may provide early warning for cancer risk elsewhere in body
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/19/2017)... ... August 18, 2017 , ... ... a transparent, verifiable database to help the cannabis industry move towards greater legitimacy. ... to deliver a faster technology with lower fees. Paragon will build a fully ...
(Date:8/19/2017)... San Diego, CA (PRWEB) , ... August 19, 2017 , ... ... Neo-Nazis, and the KKK by saying there are two sides. There are not two ... merely a way to rationalize violence and prejudice, and the NPEIV stands against all ...
(Date:8/18/2017)... , ... August 18, 2017 , ... More than 20,000 ... Republic of Congo (DRC) thanks to an ambitious venture that conjoined the passions of ... the generous support of the Liberty community. These shoes will save lives from the ...
(Date:8/18/2017)... York, NY (PRWEB) , ... August 18, 2017 ... ... edition of “Vision & Hearing” campaign, advocating for active, healthy lifestyles and highlighting ... resources available for individuals with hearing impairments and shares the latest innovations in ...
(Date:8/18/2017)... ... August 18, 2017 , ... Moore Insurance, ... communities in east Texas, is launching a regional charity effort to provide publicity ... 1991, the Pediatric Brain Tumor Foundation (PBTF) has raised nearly $30 million in ...
Breaking Medicine News(10 mins):
(Date:8/4/2017)... , Aug. 3, 2017  Agragen, LLC, a ... active in the biopharmaceutical, nutraceutical, and aquacultural feed ... of its lead drug candidates, AGR131.  This drug ... cytokine from the blood of patients suffering from ... inflammatory bowel disease. ...
(Date:8/2/2017)... CaryRx, a next-generation full-service pharmacy, has announced the ... in the Washington D.C. metropolitan area. ... delivery of medications through the convenience of its patient-friendly mobile ... within one hour to any location in D.C. ... invaluable service to Washington D.C. ," says ...
(Date:7/28/2017)... 28, 2017 Hill-Rom Holdings, Inc. ("Hill-Rom") (NYSE: ... quarter ended June 30, 2017, and updated its financial ... For the fiscal third quarter, Hill-Rom reported ... per diluted share in the prior-year period. These results ... per diluted share primarily related to the non-cash write-down ...
Breaking Medicine Technology: