Navigation Links
Early Research With Drug Restores Hair in Patients With Alopecia
Date:8/18/2014

SUNDAY, Aug. 17, 2014 (HealthDay News) -- A drug used to treat a rare type of bone marrow cancer restores hair in patients with an autoimmune disease that causes hair loss, a new study found.

Columbia University Medical Center researchers found that the drug ruxolitinib (brand name: Jakafi) restored hair growth in a small number of patients with alopecia areata, a disease in which immune cells destroy hair follicles.

Alopecia areata can occur at any age and affects men and women. Patients typically lose patches of hair on the scalp, but may also lose facial and body hair. Currently, there are no known treatments to completely restore hair in these patients, who can suffer mental and emotional stress, the researchers said.

First, the researchers identified the immune cells that destroy hair follicles in people with alopecia areata. They also discovered that ruxolitinib -- which is approved by the U.S. Food and Drug Administration to treat a bone marrow cancer called myelofibrosis -- eliminated these immune cells.

The study team first tested the drug in mice and then in a small number of people with moderate to severe alopecia areata (more than 30 percent hair loss). Within five months of starting treatment, three patients had total hair regrowth.

"We've only begun testing the drug in patients, but if the drug continues to be successful and safe, it will have a dramatic positive impact on the lives of people with this disease," study leader Dr. Raphael Clynes said in a Columbia news release.

"We still need to do more testing to establish that ruxolitinib should be used in alopecia areata, but this is exciting news for patients and their physicians," he added. "This disease has been completely understudied -- until now, only two small clinical trials evaluating targeted therapies in alopecia areata have been performed, largely because of the lack of mechanistic insight into it."

The study findings were published online Aug. 17 in the journal Nature Medicine.

More information

The American Academy of Dermatology has more about alopecia areata.

SOURCE: Columbia University, news release, Aug. 17, 2014

--


'/>"/>
Copyright©2014 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Nearly Half a Million Dollar Judgment in Favor of Nithyananda Dhyanapeetam of Ohio Issued by U.S. Federal Court [against AARTHI S. RAO]
2. Robin Williams Had Early Stage Parkinsons Disease, Wife Reveals
3. Guidelines can predict early menopause in child cancer survivors
4. USP Awards Early-Career Scientists with Fellowships Supporting Drug Quality Research
5. Nearly 1 in 5 Americans Drinks at Least 1 Soda a Day: CDC
6. IUPUI chemist to receive $600,000 early career development award from NSF
7. New Report from Consumers for Dental Choice/ Zogby Analytics Clearly Shows that Americans are Measurably Misled About the Mercury in Their Dental Fillings
8. Professor Qi Wang wins EMBS Early Career Achievement Award
9. Front-of-Head Hits Blamed for Nearly Half of Young Football Player Concussions
10. Allegheny Health Network Team Develops Biomarker for Early Detection of Esophageal Cancer
11. Nearly 10 percent of patients with cancer still smoke
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... October 13, 2017 , ... While it’s often important to take ... an inventor from Austin, Texas, has identified a solution. , She developed a prototype ... restricted lighting. As such, it eliminates the need to turn on a light when ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... Hannah Randall, PharmD ‘17, and Jennifer Huggins, PharmD ’17, along with clinical ... the primary prevention of cardiovascular diseases during the 15th Annual Women’s Health ...
(Date:10/13/2017)... ... October 13, 2017 , ... The Visiting Nurse Association (VNA) of ... collection of specialty vendors and unique items from across the nation, this holiday-themed event ... wellness services offered by the VNA. The boutique will be open Saturday, November ...
(Date:10/13/2017)... ... , ... Talented host, actor Rob Lowe, is introducing a ... episode of "Success Files," which is an award-winning educational program broadcasted on PBS ... in-depth with passion and integrity. , Sciatica occurs when the sciatic nerve in ...
(Date:10/12/2017)... ... 12, 2017 , ... First Healthcare Compliance (FHC), an industry ... a range of technology and learning solutions at the 68th Annual American Healthcare ... be held October 14–18, 2017 at the Mandalay Bay Resort in Las Vegas, ...
Breaking Medicine News(10 mins):
(Date:10/2/2017)... 2, 2017 Diplomat Pharmacy, Inc. (NYSE: ... and Consulting, LLC , and named its founder as ... in Tennessee , will operate under ... EnvoyHealth,s service offerings for health care partners to include ... "In an interoperable world, technology delivers ...
(Date:10/2/2017)... 2017  AllianceRx Walgreens Prime, the combined central specialty ... pharmacy benefit manager Prime Therapeutics LLC (Prime), today officially ... the unveiling of new signage at its headquarters in ... at a few other company-owned facilities across the country. ... some of whom will begin to see the AllianceRx ...
(Date:10/2/2017)... The Rebound mobile app is poised to become ... tide of prescription drug addiction. The app empowers users to ... stepping down their dosage in a safe, controlled manner while ... the first 100,000 people to sign up will enjoy 3 ... ...
Breaking Medicine Technology: