Navigation Links
Early Research With Drug Restores Hair in Patients With Alopecia
Date:8/18/2014

SUNDAY, Aug. 17, 2014 (HealthDay News) -- A drug used to treat a rare type of bone marrow cancer restores hair in patients with an autoimmune disease that causes hair loss, a new study found.

Columbia University Medical Center researchers found that the drug ruxolitinib (brand name: Jakafi) restored hair growth in a small number of patients with alopecia areata, a disease in which immune cells destroy hair follicles.

Alopecia areata can occur at any age and affects men and women. Patients typically lose patches of hair on the scalp, but may also lose facial and body hair. Currently, there are no known treatments to completely restore hair in these patients, who can suffer mental and emotional stress, the researchers said.

First, the researchers identified the immune cells that destroy hair follicles in people with alopecia areata. They also discovered that ruxolitinib -- which is approved by the U.S. Food and Drug Administration to treat a bone marrow cancer called myelofibrosis -- eliminated these immune cells.

The study team first tested the drug in mice and then in a small number of people with moderate to severe alopecia areata (more than 30 percent hair loss). Within five months of starting treatment, three patients had total hair regrowth.

"We've only begun testing the drug in patients, but if the drug continues to be successful and safe, it will have a dramatic positive impact on the lives of people with this disease," study leader Dr. Raphael Clynes said in a Columbia news release.

"We still need to do more testing to establish that ruxolitinib should be used in alopecia areata, but this is exciting news for patients and their physicians," he added. "This disease has been completely understudied -- until now, only two small clinical trials evaluating targeted therapies in alopecia areata have been performed, largely because of the lack of mechanistic insight into it."

The study findings were published online Aug. 17 in the journal Nature Medicine.

More information

The American Academy of Dermatology has more about alopecia areata.

SOURCE: Columbia University, news release, Aug. 17, 2014

--


'/>"/>
Copyright©2014 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Nearly Half a Million Dollar Judgment in Favor of Nithyananda Dhyanapeetam of Ohio Issued by U.S. Federal Court [against AARTHI S. RAO]
2. Robin Williams Had Early Stage Parkinsons Disease, Wife Reveals
3. Guidelines can predict early menopause in child cancer survivors
4. USP Awards Early-Career Scientists with Fellowships Supporting Drug Quality Research
5. Nearly 1 in 5 Americans Drinks at Least 1 Soda a Day: CDC
6. IUPUI chemist to receive $600,000 early career development award from NSF
7. New Report from Consumers for Dental Choice/ Zogby Analytics Clearly Shows that Americans are Measurably Misled About the Mercury in Their Dental Fillings
8. Professor Qi Wang wins EMBS Early Career Achievement Award
9. Front-of-Head Hits Blamed for Nearly Half of Young Football Player Concussions
10. Allegheny Health Network Team Develops Biomarker for Early Detection of Esophageal Cancer
11. Nearly 10 percent of patients with cancer still smoke
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/28/2017)... (PRWEB) , ... April 28, 2017 , ... ... its new partnership with the Home Care Association of America (HCAOA). This agreement ... Private Duty Accreditation services, as well as discounts on Accreditation University (AU) educational ...
(Date:4/28/2017)... ... , ... Beginning in 2017, Ridgecrest Herbals will be phasing out the homeopathic ... Extra Strength formula. To ensure that the effectiveness of Clear Lungs Extra Strength is ... , Removal of the homeopathic element , Adding their patented ...
(Date:4/28/2017)... ... April 28, 2017 , ... GlycoMark, Inc. ... GlycoMark test throughout the Northeast U.S. , GlycoMark is the only clinically ... GlycoMark test provides a clinically proven one- to two-week measure of hyperglycemic excursions, ...
(Date:4/28/2017)... Fairfax, VA (PRWEB) , ... April 28, 2017 , ... ... elected volunteer board members and officers for 2017-2018. The annual board election process has ... serving on a volunteer basis. , Thomas C. Dickerson, Ed.D., FACHE, succeeds Jim Hamilton, ...
(Date:4/28/2017)... ... , ... The Texas Cord Blood Bank (TCBB), a program of nonprofit biomedical ... Women’s Hospital at Renaissance in Edinburg for their outstanding efforts in collecting umbilical cord ... donate. , “Women’s Hospital at Renaissance has been a collection partner for the ...
Breaking Medicine News(10 mins):
(Date:4/19/2017)... 19, 2017 Global Prostate Cancer Therapeutics ... the prostate cancer therapeutics market analyzes the current ... prevalence of prostate cancer, launch of promising emerging ... of new drugs & therapeutic biological products, and ... to lesser side effects are some of the ...
(Date:4/19/2017)... DIEGO , April 19, 2017  Sorrento ... an antibody-centric, clinical-stage biopharmaceutical company developing new treatments ... announced the closing of its previously announced underwritten ... stock at a public offering price of $2.00 ... and estimated offering expenses payable by Sorrento.  The ...
(Date:4/19/2017)... , April 19, 2017  Novartis today announced ... National Heart, Lung, and Blood Institute (NHLBI) of ... 58% of patients with treatment-naïve severe aplastic anemia ... treated with eltrombopag at the initiation of and ... study evaluated three sequential treatment groups, or cohorts. ...
Breaking Medicine Technology: