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Early COPD diagnosis possible with nuclear medicine
Date:4/1/2013

ole histology slices.

Upon analysis, functional impairment was noted in the lungs due to increased inflammation and airspace enlargement. This functional impairment, measured with SPECT V/Q imaging, identified COPD characteristics before CT was able to detect structural changes in the lungs. In addition V/Q mismatching progressively increased during cigarette smoke exposure in mice compared to age-matched control mice and offered insight into the underlying pathology causing COPD.

"V/Q imaging is a common nuclear medicine technique, and SPECT/CT systems are increasingly used in clinical practice," noted Labiris. "As such, the technology examined in this study can be carried out in both preclinical and clinical settings, enabling researchers to translate preclinical investigations of disease, associated functional abnormalities and future drug targets into an improved understanding and management of the disease in patients."


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Contact: Susan Martonik
smartonik@snmmi.org
703-652-6773
Society of Nuclear Medicine
Source:Eurekalert

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