Navigation Links
Earlier HIV Treatment Could Save Lives Worldwide
Date:7/20/2009

Study looks at costs and benefits of revising treatment guidelines

MONDAY, July 20 (HealthDay News) -- Beginning antiretroviral therapy soon after an HIV diagnosis should be standard care for all, including those in poor nations where cost is a barrier, new research contends.

An estimated 76,000 deaths could be prevented and 66,000 infections avoided over a five-year period, the researchers say, if antiretroviral therapy (ART) were started when CD4 T-cell levels drop below 350 per microliter of blood instead of delaying until levels fall below 250. Their study is reported in the Aug. 4 issue of Annals of Internal Medicine.

"The time has come to act on the information we now have, nearly all of which supports starting treatment earlier," said study co-author Robin Wood, director of the Desmond Tutu HIV Centre at the University of Cape Town in South Africa, in a news release about the study. South Africa currently has the highest rates of HIV infection in the world.

Because ART is expensive and can have significant side effects, World Health Organization treatment guidelines issued in 2006 suggested waiting until CD4 counts drop below 200 per microliter of blood or until people developed AIDS-related complications. The CD4 count reflects immune system function.

In developed nations, including the United States, ART is typically started when the CD4 count drops below 350, according to the study. Applying a similar standard in countries with limited financial resources would save lives and be cost effective, the researchers say.

The study estimated the cost at $1,200 per year of life saved.

"While those standards accommodate the limited resources and short supply of medications in many settings, the greater prevalence of tuberculosis and other opportunistic infections in places like South Africa argue for earlier treatment initiation, even before the results of ongoing clinical trials are known," said the study's lead author, Dr. Rochelle Walensky, of the division of infectious disease at Massachusetts General Hospital in Boston.

The researchers used mathematical modeling to simulate HIV treatment and calculate the possible health and economic outcomes. The model determined the additional costs of earlier treatment, potential toxicities and benefits. It also looked at the cost-effectiveness of earlier ART initiation.

More information

The U.S. Centers for Disease Control and Prevention has more on HIV/AIDS.



-- Jennifer Thomas



SOURCE: Massachusetts General Hospital, news release, July 20, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Earlier Testing Needed for Fragile X Syndrome
2. Signs of Alzheimers Seen Earlier Than Thought
3. Chemical Nose May Sniff Out Cancer Earlier
4. Clues to Alzheimers Spotted Earlier in Disease
5. Underweight and extremely obese die earlier than people of normal weight, study finds
6. Underweight and Extremely Obese Die Earlier Than People of Normal Weight, Study Finds
7. Cerebrospinal fluid shows Alzheimers disease deterioration much earlier
8. Immune Defense - the Earlier, the Better: Expert Cites Supplement from Pure Research Products
9. Diagnosis of arthritis 5 years earlier in childless women compared to those with children
10. Viewing Adult-Themed TV Tied to Earlier Sex for Teens
11. Children who view adult-targeted TV may become sexually active earlier in life
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Earlier HIV Treatment Could Save Lives Worldwide
(Date:2/10/2016)... ... February 10, 2016 , ... 10 Best Water is excited to ... water brand owners that topped the list as a result of their commitment to ... premier brand was Tibet 5100, a top notch water company that specializes in providing ...
(Date:2/10/2016)... ... February 10, 2016 , ... Intalere’s 2016 ... more than 200 of the country’s top healthcare executives to share insights on ... benefit of the Forum is the provider-centric perspective, experience, expertise and strategy shared ...
(Date:2/10/2016)... ... February 10, 2016 , ... Armune BioScience ... across their network of laboratory service centers across the country. Launched in April of ... in the detection of prostate cancer. Apifiny order volume exceeded 3,000 tests in 2015. ...
(Date:2/10/2016)... ... February 10, 2016 , ... ... the Ohio Safety Congress and Expo event March 9-11, 2016. Hosted by Ohio's ... Convention Center. , As the longest running and largest worker's compensation event ...
(Date:2/10/2016)... ... February 10, 2016 , ... ... February 26th: Amateur & Professional Divisions - Time: 7:00pm – 10:00pm | ... | Ticket Prices $30, Social Media: http://www.USPoleSportsFed.org , Facebook: http://www.facebook.com/uspolesportsfederation ...
Breaking Medicine News(10 mins):
(Date:2/10/2016)... -- Vanda Pharmaceuticals Inc. (Vanda) (NASDAQ: VNDA ), ... quarter and full year ended December 31, 2015. ... a transformational year for Vanda with the continued growth ... approval of HETLIOZ for Non-24," said Mihael H. Polymeropoulos, ... to our U.S. product portfolio builds on this success ...
(Date:2/10/2016)... --> --> This press release is intended for ... Japan .  --> A separate press release has been prepared ... Shire continues to strengthen its presence in ... continues to strengthen its presence in Japan ... continues to strengthen its presence in Japan ...
(Date:2/10/2016)... A new report from business intelligence provider GBI Research ... Alzheimer,s disease market will more than double from just under $5 billion in ... Rate (CAGR) of 11%. Canada , France ... Spain , the UK, and Japan , and ... --> Canada , France , ...
Breaking Medicine Technology: