Navigation Links
Earlier HIV Treatment Could Save Lives Worldwide
Date:7/20/2009

Study looks at costs and benefits of revising treatment guidelines

MONDAY, July 20 (HealthDay News) -- Beginning antiretroviral therapy soon after an HIV diagnosis should be standard care for all, including those in poor nations where cost is a barrier, new research contends.

An estimated 76,000 deaths could be prevented and 66,000 infections avoided over a five-year period, the researchers say, if antiretroviral therapy (ART) were started when CD4 T-cell levels drop below 350 per microliter of blood instead of delaying until levels fall below 250. Their study is reported in the Aug. 4 issue of Annals of Internal Medicine.

"The time has come to act on the information we now have, nearly all of which supports starting treatment earlier," said study co-author Robin Wood, director of the Desmond Tutu HIV Centre at the University of Cape Town in South Africa, in a news release about the study. South Africa currently has the highest rates of HIV infection in the world.

Because ART is expensive and can have significant side effects, World Health Organization treatment guidelines issued in 2006 suggested waiting until CD4 counts drop below 200 per microliter of blood or until people developed AIDS-related complications. The CD4 count reflects immune system function.

In developed nations, including the United States, ART is typically started when the CD4 count drops below 350, according to the study. Applying a similar standard in countries with limited financial resources would save lives and be cost effective, the researchers say.

The study estimated the cost at $1,200 per year of life saved.

"While those standards accommodate the limited resources and short supply of medications in many settings, the greater prevalence of tuberculosis and other opportunistic infections in places like South Africa argue for earlier treatment initiation, even before the results of ongoing clinical trials are known," said the study's lead author, Dr. Rochelle Walensky, of the division of infectious disease at Massachusetts General Hospital in Boston.

The researchers used mathematical modeling to simulate HIV treatment and calculate the possible health and economic outcomes. The model determined the additional costs of earlier treatment, potential toxicities and benefits. It also looked at the cost-effectiveness of earlier ART initiation.

More information

The U.S. Centers for Disease Control and Prevention has more on HIV/AIDS.



-- Jennifer Thomas



SOURCE: Massachusetts General Hospital, news release, July 20, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Earlier Testing Needed for Fragile X Syndrome
2. Signs of Alzheimers Seen Earlier Than Thought
3. Chemical Nose May Sniff Out Cancer Earlier
4. Clues to Alzheimers Spotted Earlier in Disease
5. Underweight and extremely obese die earlier than people of normal weight, study finds
6. Underweight and Extremely Obese Die Earlier Than People of Normal Weight, Study Finds
7. Cerebrospinal fluid shows Alzheimers disease deterioration much earlier
8. Immune Defense - the Earlier, the Better: Expert Cites Supplement from Pure Research Products
9. Diagnosis of arthritis 5 years earlier in childless women compared to those with children
10. Viewing Adult-Themed TV Tied to Earlier Sex for Teens
11. Children who view adult-targeted TV may become sexually active earlier in life
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Earlier HIV Treatment Could Save Lives Worldwide
(Date:3/28/2017)... San Francisco, CA (PRWEB) , ... March 28, 2017 , ... ... million people suffering from acne, access to quality care can be limited while the ... skincare company that offers customized prescription acne care for every customer online, today released ...
(Date:3/28/2017)... ... 28, 2017 , ... Columbus OH. Dr. Justin Harper, Founder of Juvly Aesthetics ... in the country to sit on the 2017 National Advisory Board for Allergan’s Facial ... Dr. Harper helped propel the clinic from a small start-up to number 78 in ...
(Date:3/28/2017)... PA (PRWEB) , ... March 28, 2017 , ... Public ... and across a variety of business channels. , While many results are clear, ... any public relations program. , When it comes to measurement, firms should always ...
(Date:3/28/2017)... (PRWEB) , ... March 28, 2017 , ... Oily skin is a common and unwelcomed ... Advanced Dermatology has a lot to offer to the discussion of dealing with excess ... is that there are many home remedies that can help remove the oily shine while ...
(Date:3/28/2017)... (PRWEB) , ... March 28, 2017 , ... Bacteria and fungi are probably not the ... are bad. In fact, including the right microorganisms in your diet can actually improve health ... foods. , This is the topic of a new peer-reviewed paper led ...
Breaking Medicine News(10 mins):
(Date:3/28/2017)... 2017  CASI Pharmaceuticals, Inc. (Nasdaq: CASI), a ... and other unmet medical needs, announced today two ... Research annual meeting.  The first poster to be ... of ENMD-2076 in Combination with Anti-PD1 in Syngeneic ... be presented on April 4 is entitled " ...
(Date:3/28/2017)... , March 28, 2017 Elysium ... with Cambridge academic ...   The Milner Therapeutics Institute today announces Elysium ... Health has committed significant investment for collaborative projects with academic ... four years. This is the first major research investment outside ...
(Date:3/27/2017)...  A recent study at Shriners Hospitals for Children ... the country dedicated to the treatment of pediatric burns ... the Surfacide Helios ® UV-C Disinfection System is ... pathogens not killed by the EVS (manual) cleaning process ... Burn Association,s 49th Annual Meeting in Boston ...
Breaking Medicine Technology: