"The EVINCI results will probably show that a number of invasive coronary angiography procedures are unnecessary," says Dr Neglia. "In these patients a non-invasive diagnostic imaging test can be performed, which would save money and be safer for patients."
Costs, potential risks of each procedure and patients' perception of health status are being evaluated in a health economic analysis comparing each diagnostic strategy. Some variability, particularly in costs, is expected among participating countries. Dr Neglia says: "The EVINCI study was intended to compare differences among procedures but it will also probably provide evidence for some variability in costs for the same procedure throughout Europe."
A huge European digital bank for multimodal cardiovascular imaging and biological bank for blood samples were created that will be relevant not only for the EVINCI study results but also for future studies and educational purposes.
EVINCI received funding from the European Commission within the Seventh Framework Programme (FP7) for Research and Technological Development. This is the EU's main instrument for funding research in Europe and will run from 2007-2013. FP7 is also designed to respond to Europe's employment needs, competitiveness and quality of life.
EVINCI has been a collaborative effort by 20 partners the 17 clinical centres, the ESC, the Italian National Research Council (CNR) and CF Consulting in Milan.
A major output from the trial is eduCAD, a new web based tool for disseminating the design and approach of the EVINCI study and for training young cardiologists how to choose the best imaging test for diagnosing ischaemic heart disease. eduCAD is based on clinical cases selected from the EVINCI study and has the results of multiple non-invasive imaging tests and coronary angiography for each patient. It is available at
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European Society of Cardiology