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EVINCI results could lead to 75 percent reduction of invasive procedures for patients with suspected CAD
Date:6/26/2012

can be avoided.

To this end, non-invasive imaging tests were chosen which would assess both coronary anatomic abnormalities and their functional effects. In each patient, coronary anatomy was assessed using multi-slice CT. Radionuclide imaging (either SPECT or PET) was used to measure myocardial perfusion at rest and during stress. The effects of myocardial ischaemia on ventricular function were assessed by either magnetic resonance imaging or echocardiography during stress. Patients were followed up for a maximum of three years.

Data collection concluded on 15 June. Preliminary analysis shows that in patients with stable angina or angina-like symptoms, the probability of significant coronary artery disease, based on clinical and stress electrocardiogram (ECG) evaluation, is currently largely overestimated. As a consequence many patients may receive unnecessary invasive procedures. The average estimated probability of disease in the EVINCI population was 60% while the actual prevalence of significant coronary disease, confirmed at heart catheterization and deserving revascularization, was only 25%.

Once the final analysis is completed, the EVINCI study is expected to demonstrate that performing adequate non-invasive imaging screening of patients with suspected coronary artery disease could safely avoid invasive procedures in 75 out of 100 patients. Non-invasive cardiovascular imaging has a crucial role in identifying patients with significant coronary artery disease - ie an obstructive coronary stenosis able to cause ischemia and thus deserving revascularization - prior to invasive coronary angiography. This will reduce the use of inappropriate invasive procedures and related costs, reduce risks for patients, and enable patients who are truly at risk to be effectively treated. The EVINCI study will have sufficient power to answer the question of which is the most cost effective non-invasive imaging strategy to do the job. Final results
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Contact: ESC Press Office
press@escardio.org
33-492-947-756
European Society of Cardiology
Source:Eurekalert

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