Navigation Links
EULAR issues updated rheumatoid arthritis management recommendations
Date:7/3/2013

The European League Against Rheumatism (EULAR) has released updated recommendations for the management of RA. According to this latest guidance, treatment with disease-modifying anti-rheumatic drugs (DMARDs) should be initiated as soon as a diagnosis of RA is made, with the aim of reaching a target of remission or low disease activity in every patient.

As first-line treatment, EULAR recommends rheumatologists administer methotrexate (MTX) or combination therapy of MTX with other conventional synthetic DMARDs. Low-dose glucocorticoids should also be considered in combination with DMARDs for up to six months, but should be tapered as soon as clinically feasible.

"These recommendations were based on three extensive literature reviews of the efficacy and safety of biological and conventional DMARDs, and address a number of common misinterpretations of the 2010 guidelines," according to Professor Josef Smolen, Medical University of Vienna and Hietzing Hospital, Vienna. "As already stated in 2010, by advocating the use of synthetic DMARDs, rather than biologics, as the first-line treatment this approach avoids the over-treatment of 20-50% of patients with early RA, who will achieve the treatment target with such initial therapy" he concluded for the Task Force.

However, in patients failing to respond to this treatment within 6 months and when poor prognostic factors are present, biological DMARDs (TNF-inhibitors, abatacept or tocilizumab or under certain circumstances rituximab) should be administered in combination with MTX.

The document further recommends that patients who have failed to respond to an initial biologic DMARD should receive another biologic DMARD. Patients who have failed to respond to an initial TNF-inhibitor may receive another TNF-inhibitor, or a biologic with an alternative mode of action. If biologic treatment has failed, tofacitinib may be considered where approved.

"Although the European Medicin
'/>"/>

Contact: EULAR Press Office
eularpressoffice@cohnwolfe.com
44-020-733-15364
European League Against Rheumatism
Source:Eurekalert

Page: 1 2

Related medicine news :

1. UCSF chancellor issues call-to-arms to patient advocates
2. Radiologists rank themselves as less than competent on health policy issues
3. Genetic abnormalities in benign or malignant tissues predict relapse of prostate cancer
4. FDA Issues Multiple Sclerosis Drug Alert
5. Quality of care, other issues may cause worse results in black prostate cancer surgery patients
6. U.S. Task Force Issues Blood Pressure Guidelines
7. Internists in Washington to discuss patient and professional issues in meetings on Capitol Hill
8. Cheaper drug could lead to serious eye issues
9. Insulite Labs announces the launch of the PCOS Inspiration Hour, a one hour virtual gathering place for women with PCOS and other women’s health issues to come together.
10. LawyersandSettlements.com Issues Report on Prostate Health Claim Lawsuits and Propecia Side Effect Litigation
11. What Men Should Know About Veins: Varicose Veins and Venous Disease are Real Medical Issues
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/26/2014)... 2014 According to the Metabolic Enhancement ... a comprehensive bodybuilding program that helps men lose body ... steroids . The program also instructs men how to ... , Vkool reveals in its review that this program ... help men get ripped and jacked at the same ...
(Date:7/25/2014)... July 26, 2014 Dental Perfection, a ... dental services including general dentistry, clear braces and much ... September this year in Derby. The new practice, which ... HollyBrook Medical Centre in Littleover, Derby. Patients may already ... , The new dental practice, which is headed by ...
(Date:7/25/2014)... (PRWEB) July 26, 2014 According ... Monitoring Market by Product (vibration monitoring, thermography, ultrasound ... signature analysis), Component, Application and Geography - Global ... the machine health monitoring market is expected to ... 2014 to 2020. , Browse 117 market data ...
(Date:7/25/2014)... Ticket Down announces that they ... Guinness International Champions Cup match between international soccer powerhouses ... on Sunday, July 27th. This well-known ticket ... SOCCER-2014 for added savings. , 2014 is turning out ... in North America. Countless international soccer teams have been ...
(Date:7/25/2014)... USA (PRWEB) July 25, 2014 As reported ... Use, OD Deaths Increase (7/20), Michigan has seen a nearly ... four years. While the count was 271 between 1999 and ... range. DEA Agents believe that, like other states, drug users ... the drug via prescription pills. He compared the price of ...
Breaking Medicine News(10 mins):Health News:Metabolic Enhancement Training Review Exposes Scott Abel's Program for Bodybuilding – Vkool.com 2Health News:Metabolic Enhancement Training Review Exposes Scott Abel's Program for Bodybuilding – Vkool.com 3Health News:Derby Cosmetic Dentist Dental Perfection to Open New Practice in Littleover, Derby this September 2Health News:Machine Health Monitoring Market by Product, Component & Application Worth $2.50 Billion by 2020 - New Report by MarketsandMarkets 2Health News:Machine Health Monitoring Market by Product, Component & Application Worth $2.50 Billion by 2020 - New Report by MarketsandMarkets 3Health News:Machine Health Monitoring Market by Product, Component & Application Worth $2.50 Billion by 2020 - New Report by MarketsandMarkets 4Health News:Liverpool FC vs. Olympiacos FC Tickets Soldier Field: Ticket Down Slashes Ticket Prices for Guinness International Champions Cup in Chicago on Sunday, July 27th 2Health News:Rise in Heroin Use, Overdose Deaths in Michigan 2
... ... concern of hospitals is keeping their patients safe while within their facility. To ... identifiers to patients that may present a higher risk of falling while in ... for a variety of reasons, have a higher than normal risk of being ...
... ... survivor and inspirational comedian, Hugh Chatfield, to host “Inspiration for Injured Service Members ... by nationally-recognized and sought-after comedian, Bob Marley, and USMC Vet, funnyman George Hamm. ... ...
... , HOUSTON , Jan. 14 ... was named the 2009 Marathon Oil Corporation Paul "Bear" Bryant Coach ... a coach has received the award twice. , Petersen was ... at an awards dinner Thursday evening in Houston , which ...
... , , Twenty-one ... , Jan. 14 More than 300 regulatory professionals ... most recent exam period for the professional certification. Candidates for the ... in autumn of 2009, with 315 achieving a passing score. Twenty-one ...
... RESEDA, Calif. , Jan. 14 ... Jewish Home in Reseda, CA , has been selected ... its Delegate to AAHSA, the American Association of Homes and ... membership at the AAHSA House of Delegates. , (Photo: ...
... , , LOS ANGELES , ... and Gibson, Dunn & Crutcher LLP filed a class ... children with autism against the Eastern Los Angeles Regional ... for their condition.  ELARC, a nonprofit agency through which ...
Cached Medicine News:Health News:Midbrook Assists Local Hospital with Fall Kit Production 2Health News:Midbrook Assists Local Hospital with Fall Kit Production 3Health News:Inspirational Comedy Night to Give Hope and Laughter to Iraq/Afghanistan Injured Veterans and Service Members 2Health News:Boise State's Chris Petersen Becomes First Repeat Winner of the Paul 'Bear' Bryant Coach of the Year Award 2Health News:More Than 300 Earn Regulatory Affairs Certification (RAC), the Only Professional Certification for the Healthcare Product Regulatory Field 2Health News:More Than 300 Earn Regulatory Affairs Certification (RAC), the Only Professional Certification for the Healthcare Product Regulatory Field 3Health News:Molly Forrest, CEO-President of the Los Angeles Jewish Home, Elected to Aging Services of California Board of Directors 2Health News:Molly Forrest, CEO-President of the Los Angeles Jewish Home, Elected to Aging Services of California Board of Directors 3Health News:Molly Forrest, CEO-President of the Los Angeles Jewish Home, Elected to Aging Services of California Board of Directors 4Health News:Class Action Suit Filed to Defend Rights of Children With Autism to Vital, Cost-Saving Treatment 2Health News:Class Action Suit Filed to Defend Rights of Children With Autism to Vital, Cost-Saving Treatment 3
(Date:7/25/2014)... MEXICO CITY , July 25, 2014 ... a Latin American healthcare sciences publisher, launched a library ... on conditions such as cancer and heart disease. Healthcare ... most up-to-date information to deliver better patient care. ... rapidly, with many relying on smartphones and tablets to ...
(Date:7/25/2014)... Inc. (NASDAQ: IDXX ) today reported that ... versus the prior year period to $390 million. Organic ... 2014 versus the prior year period was 9%, or ... Earnings per diluted share ("EPS") for the quarter ended ... period to $1.10."In the second quarter, we continued to ...
(Date:7/25/2014)... , July 25, 2014  Semler Scientific, Inc. ... medical risk assessment company that develops patented products ... evaluating chronic diseases, today reported financial results for ... 30, 2014. "The second quarter ... said Doug Murphy-Chutorian , M.D., chief executive ...
Breaking Medicine Technology:Healthcare Sciences Publisher PLM and IBM Speed Access to Medical Information to Deliver Better Patient Care with Mobile 2Healthcare Sciences Publisher PLM and IBM Speed Access to Medical Information to Deliver Better Patient Care with Mobile 3Healthcare Sciences Publisher PLM and IBM Speed Access to Medical Information to Deliver Better Patient Care with Mobile 4IDEXX Laboratories Announces Second Quarter Results 2IDEXX Laboratories Announces Second Quarter Results 3IDEXX Laboratories Announces Second Quarter Results 4IDEXX Laboratories Announces Second Quarter Results 5IDEXX Laboratories Announces Second Quarter Results 6IDEXX Laboratories Announces Second Quarter Results 7IDEXX Laboratories Announces Second Quarter Results 8IDEXX Laboratories Announces Second Quarter Results 9IDEXX Laboratories Announces Second Quarter Results 10IDEXX Laboratories Announces Second Quarter Results 11IDEXX Laboratories Announces Second Quarter Results 12IDEXX Laboratories Announces Second Quarter Results 13IDEXX Laboratories Announces Second Quarter Results 14IDEXX Laboratories Announces Second Quarter Results 15IDEXX Laboratories Announces Second Quarter Results 16IDEXX Laboratories Announces Second Quarter Results 17IDEXX Laboratories Announces Second Quarter Results 18IDEXX Laboratories Announces Second Quarter Results 19IDEXX Laboratories Announces Second Quarter Results 20IDEXX Laboratories Announces Second Quarter Results 21IDEXX Laboratories Announces Second Quarter Results 22IDEXX Laboratories Announces Second Quarter Results 23IDEXX Laboratories Announces Second Quarter Results 24IDEXX Laboratories Announces Second Quarter Results 25IDEXX Laboratories Announces Second Quarter Results 26IDEXX Laboratories Announces Second Quarter Results 27IDEXX Laboratories Announces Second Quarter Results 28IDEXX Laboratories Announces Second Quarter Results 29IDEXX Laboratories Announces Second Quarter Results 30IDEXX Laboratories Announces Second Quarter Results 31IDEXX Laboratories Announces Second Quarter Results 32IDEXX Laboratories Announces Second Quarter Results 33
... at High,Risk , ,WASHINGTON, March 9, 2007 ... history of end-stage renal disease (ESRD), and,these individuals appear ... reports a study in the April Journal of,the American ... disease is more frequent in,African-Americans, who are also at ...
... Pharmaceuticals,Inc. (OTCBB:CGXP), a biopharmaceutical company focused on,infectious ... catheter,treated with a Ceragenin compound demonstrated virtually ... In the study, polyurethane catheters treated with ... along with an,untreated catheter. At day 21, ...
Cached Medicine Technology:Nearly 1 in 10 Americans Has A Relative With Kidney Failure 2Ceragenix Announces Ceragenins Virtually Prevent Catheter Biofilm,Formation in 21 Day Study 2Ceragenix Announces Ceragenins Virtually Prevent Catheter Biofilm,Formation in 21 Day Study 3
Substrate Plasma for Factor IX Assay by STA© Analyzers. Freeze-dried human plasma from which factor IX has been removed by selective immuno-adsorption....
Enzyme Immunoassay of von Willebrand Factor Antigenby ELISA Method, 96 tests....
Enzyme Immunoassay of Factor IX Antigen by ELISA Method, 96 tests....
Enzyme Immunoassay of Platelet Factor 4 Antigen by ELISA Method, 96 tests....
Medicine Products: