Navigation Links
ESC pilot registry in heart failure reflects improvement in chronic disease

With the increased prevalence of chronic heart failure (HF), there is a concomitant increase in the number of related hospitalisations; as chronic HF progresses, the risk of acute exacerbation increases.

Registries and surveys of HF have been generally conducted in patients with either chronic or acute conditions, but a description of the whole clinical history of patients with HF, including the acute episodes, consequent changes in clinical conditions and management strategies, have not been available.

The final results of the Heart Failure Pilot Study, a general registry of the ESC's ongoing EurObservational Research Programme (EORP), now provide improved information on the epidemiology and outcomes of real world patients with this clinical condition.

The HF pilot study was a prospective observational survey conducted in 136 cardiology centers in 12 European countries selected to represent the different health systems and care attitudes across Europe. From October 2009 to May 2010, 5118 patients were included, 1892 (37%) admitted for acute HF, and 3226 (63%) with chronic HF. All were followed-up for the subsequent year, and the study was terminated at the end of May 2011. Just 5% of the patients were lost to follow-up.

Results showed that, while the mortality rate of patients with chronic HF seems to be improving (7% after one year of follow-up), outcomes of acute HF patients are still unacceptably poor at one year - an all-cause mortality rate of nearly 17% and a combined outcome measure of all-cause mortality or hospitalisation of 35%.

The outcome improvement in ambulatory patients with chronic HF could be explained by the fact that European cardiologists prescribe a high rate of guideline-recommended pharmacological treatments, such as the blockers of the renin-angiotensin-aldosterone system and beta-blockers. The study showed that these treatments were not only prescribed appropriately but were maintained over the whole one-year follow-up period.

Unlike patients with chronic HF, those admitted for acute HF were still treated more anecdotally than according to evidence-based medicine. "This may be," explained Professor Aldo Maggioni from the Centro Studi ANMCO in Florence, Italy, " because of a lack, in this specific clinical context, of specific controlled studies demonstrating effective treatment strategies for improving outcomes. And this could be the reason for the still high observed mortality and morbidity rates in acute HF patients."

As expected, the great majority of the causes of death, both in acute and chronic HF was cardiovascular, and sudden in 40% of cases; the most frequent cause of hospitalisation or re-hospitalisation was HF.

Professor Maggioni added: "The study has also allowed us to identify several independent predictors of outcome, which will be useful for implementing ad hoc strategies in very high risk patients with this severe clinical condition."

The pilot study has paved the way for implementation of a pan-ESC long-term registry which began data collection in May 2011 with the participation of 32 European countries.


Contact: Jacqueline Partarrieu
European Society of Cardiology

Related medicine news :

1. Pilot Testing Phase Ends; Expansion Of Sales Force Begins
2. Surgeons pilot prevention program reduces incidence of postoperative pneumonia
3. Proximity Systems Announces First Large Sale of New LAN Based Electronic Lock Management System; Completion of Four Pilot Installations
4. The American Breast Cancer Foundation Partners with Pilot Pen to Raise Breast Cancer Awareness Nation-Wide
5. Pilot study supports adolescent diabetes patients through personalized text messages
6. Pilot safety protocol could help dentists reduce errors
7. University of Colorado in pilot project to map defibrillators
8. 2 people receive kidney transplants in pilot program using CMU software
9. In pilot study, screening detects potentially serious heart conditions in healthy children
10. Pilot study examines stress, anxiety and needs of young women with a unique breast cancer
11. Long Commutes for Pilots May Hamper Flying Performance: Study
Post Your Comments:
(Date:12/1/2015)... IL (PRWEB) , ... December 01, 2015 , ... ... keeping their independence is everything. That is why Hollister Incorporated has launched the ... to offer this next product in the VaPro touch free catheter portfolio,” said ...
(Date:12/1/2015)... (PRWEB) , ... December 01, 2015 , ... ... that it has been selected as a finalist in this year’s Fierce Innovation ... FierceMobileHealthcare. Next IT Healthcare was recognized as a finalist in the category of ...
(Date:12/1/2015)... ... December 01, 2015 , ... TCS Healthcare Technologies (TCS), a ... health arenas, is pleased to announce that VIP Care Services, a Caprock Health ... the ACUITY Complete Care™ Management to back their collaborative catastrophic case management initiatives. ...
(Date:12/1/2015)... ... 2015 , ... PartnerTech , a leader in high-tech ... 2008. Gary Bruce, President of PartnerTech North America, currently serves as Director for ... of time in Sweden since joining PartnerTech based in Malmo, Sweden. He has ...
(Date:12/1/2015)... ... 01, 2015 , ... Dr. Arash Moradzadeh of was ... , Angeleno Magazine is a division of Modern Luxury, which is the ... includes more than 50 magazine titles across 15 major markets. The magazine reaches ...
Breaking Medicine News(10 mins):
(Date:12/1/2015)... Dec. 1, 2015 As enforcement of the ... Security Act (DSCSA) approaches, InfiniTrak announced ... pharmacies comply with looming FDA regulations. ... entering endorsement agreements with State Pharmacy Associations, an ... organization (PSAO) to exclusively provide the InfiniTrak track-and-trace ...
(Date:12/1/2015)... CLEVELAND , Dec. 1, 2015   ... innovation firm, today announced the publication of a ... Entering the Direct-to-Consumer Medical Market". The whitepaper gives ... roadmap for successfully penetrating this lucrative segment. ... purchase healthcare products to manage their own health, ...
(Date:12/1/2015)... 2015 --> --> ... Market by Type of Drug (Monoclonal Antibodies, Interferon-Alpha, Interleukins, Vaccines, ... Pipeline Analysis - Global Forecast to 2020", published by MarketsandMarkets, ... 73,529.2 Million by 2020 from USD 40,281.6 Million in 2015, ... Browse 37 market data T ...
Breaking Medicine Technology: