Navigation Links
ESC announces review of Atrial Fibrillation Guidelines
Date:8/4/2011

The Guidelines Department of the European Society of Cardiology has issued the following statement today:

"The European Society of Cardiology (ESC) is aware of the early termination of the PALLAS trial (a randomised dronedarone versus placebo outcomes study in patients with permanent atrial fibrillation and cardiovascular risk) because of adverse outcomes associated with dronedarone.

Current ESC Guidelines for the Management of Atrial Fibrillation (AF) recommend the use of dronedarone in patients with atrial fibrillation as an antiarrhythmic agent, to prevent recurrence of the arrhythmia and to reduce the ventricular rate in patients with non-permanent atrial fibrillation (strictly in accordance with the indications approved by the European Medicines Agency) and to prevent cardiovascular hospital admissions (in line with the FDA approved indication, and consistent with the data included within the Summary of Product Characteristics approved by the EMA).

The European Guidelines strongly advise against administration of dronedarone to any patient with NYHA Class III or IV or recently unstable (decompensation within the last 4 weeks) heart failure.

Both the EMA and FDA have advised that the use of dronedarone should be restricted to the approved indications, and that dronedarone should not be used in patients with permanent atrial fibrillation. The ESC Guidelines are consistent with this advice.

Both agencies are presently reviewing the benefit-risk of dronedarone and will issue new regulations for dronedarone in due course. The ESC will produce a focused update of the AF Guidelines when the full results of PALLAS have been published and regulatory authorities have revised the labelling for dronedarone. The focused update of the AF Guidelines will also allow the incorporation of formal recommendations relating to the use of vernakalant, one or more of the new anticoagulant agents that are alternatives to warfarin, and left atrial appendage closure devices."

In a previous statement issued on 18 July 2011, the ESC had advised patients currently taking dronedarone not to stop their therapy and to consult their treating physician should they have any questions.


'/>"/>

Contact: Jacqueline Partarrieu
press@escardio.org
33-489-872-044
European Society of Cardiology
Source:Eurekalert

Related medicine news :

1. Lincare Holdings Inc. Announces Fourth Quarter and Year Ended 2009 Financial Results
2. Connecture, Inc. Announces Partnership with MedicareCRM
3. Chiquita Announces Support for School Salad Bar Campaign
4. Team Health Holdings, Inc., Announces Fourth Quarter and Fiscal 2009 Financial Results
5. MDS Announces Agreements to Divest MDS Pharma Services Early Stage Business
6. MyDietShopz.com Announces Biggest Losers Contest - Share Your Story To Inspire Others
7. Rocketboy Media Wins Award for Masonic Lodge Web Site; Announces Signing of Several New Clients
8. Emergency Nurses Association Announces Corporate Sponsors for Leadership Conference
9. Whitemark Homes Inc. Announces Change of Auditors and Additional Corporate Information
10. Sunquest Announces Major Software Updates and Enhancements
11. Data Strategy Announces SurePath Services Offering for EMC Avamar
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2017)... ... 2017 , ... Zifam Pinnacle, an Australian company dedicated to providing a unique ... buyers at the January ECRM Trade Show in Hilton Head, SC. , Zifam Pinnacle ... in all of its creations to help create a more traditional and natural approach ...
(Date:1/21/2017)... ... , ... Caronlab Australia, an Australian company known for health and beauty products ... SC, where it benefited from outstanding meetings with major retail buyers. , Caron Labs ... At this trade show, the company had the chance to demonstrate its products and ...
(Date:1/21/2017)... ... ... the largest manufacturer of oats in China, is now aiming at global business expansion, ... globally as one of the healthiest cereals, XieQingkui, the founder of Seamild, strongly recommends ... sow the seed of good karma. Buddhism spirit featuring benevolence and sacrifice are the ...
(Date:1/21/2017)... ... January 21, 2017 , ... Northern California Medical Associates ... joined their multi-specialty medical group. The dermatology practice provides general dermatologic treatment, outpatient ... to add this excellent dermatology practice to our group’s medical services,” explains NCMA ...
(Date:1/21/2017)... , ... January 21, 2017 , ... ... Austin, Texas Periodontist Dr. Dan Holtzclaw in media for its creos™ line of ... surgeries performed by Dr. Holtzclaw in which he utilizes creos™ allo.gain™ bone graft ...
Breaking Medicine News(10 mins):
(Date:1/23/2017)... 2017 The global  anxiety disorders and depression treatment market ... rising incidence of depression worldwide is anticipated to drive the market growth in ... declining demand for antidepressants in the recent years. ... ... Logo ...
(Date:1/23/2017)... SAN DIEGO and PALMA, ... Laboratoris Sanifit S.L., a clinical-stage biopharmaceutical ... announced that the first patient has been enrolled ... of lead candidate, SNF472, for the treatment of ... haemodialysis (HD). Most ESRD patients, in ...
(Date:1/23/2017)... , Jan. 23, 2017 Just two weeks remain until ... intellectual property, gather in Central London to discuss ... its kind in the market, Parallel Trade 2017 . ... preliminary list of attendees which is available to read in the event ... ...
Breaking Medicine Technology: