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ESA to Launch Corona(R) ultra(TM) at Pittcon 2009: Booth #1080

New Charged Aerosol Detector Designed for Ultra-High Performance Liquid Chromatography (UHPLC) Applications; Company will also Launch New Coulometric UHPLC Cell

CHELMSFORD, Mass., March 2 /PRNewswire/ -- ESA Biosciences, Inc., a Magellan Biosciences company and leader in novel HPLC systems that improve results for pharmaceutical development and QA/QC, life science, and analytical-chemistry customers worldwide, will launch a new, ultra-high-performance version of its award-winning Corona CAD at Pittcon 2009. Fully stackable, with the utmost in sensitivity and flexibility, ESA designed the Corona ultra so that scientists can take full advantage of the speed and increased resolution that UHPLC systems are bringing to today's challenging applications. Pittcon 2009 will be held March 9-12 at McCormick Place in Chicago, Illinois.

Commenting on the new Corona ultra detector, Jasmine Gruia-Gray, PhD, president of ESA's life science tools business, said, "Drug formulations are increasingly complex; analytical scientists can't afford to miss even the lowest concentration of impurities, which is why our Corona CAD has become a key analytical tool in the pharmaceutical industry. Breakdown products and impurities may lose their UV response, so they're easy to overlook with other detectors. Our charged aerosol detection technology lets you see any non-volatile analyte, even those without a chromophore. Speed is also important and the leading pharmaceutical development and QA/QC operations have been migrating to a UHPLC environment. We designed the new Corona ultra to customer specifications. It delivers the increased resolution and performance that other detectors can't match, with the cost and time savings of high-speed analysis - plus, it's rugged and stackable so it fits easily in any lab - no additional bench space necessary."

Besides excellent sensitivity, the Corona ultra shows consistent inter-analyte response independent of chemical structure. This breakthrough detector can effectively analyze a wide diversity of chemical structures and important classes of molecules - from small organic molecules, proteins and peptides, to ions, carbohydrates, lipids, and polymers. The Corona ultra makes methods development, validation, and transfer fast and easy for a wide range of life-science research applications and industries: pharmaceutical, chemical, polymer, food and beverage, biofuel, oils, petrochemical, and more. For more information, visit

    Corona ultra features & benefits

    UHPLC compatible   -- Faster chromatography methods with higher resolution
                       -- Compatible with traditional HPLC
                       -- Maintains high resolution while reducing analysis

    Heated/Cooled      -- Flexibility to develop methods for various types of
     nebulizer             analytes
                       -- More precise nebulization temperature control

    Dynamic range      Enabling detection over four orders of magnitude e.g.
                       API and impurities in the same run

    Sensitivity        10 ng on column, enabling detection of impurities

    Customer Care      ESA provides you with the highest standard in customer
     Program           care to ensure customer confidence, security,
                       knowledge, and support

In addition to the Corona ultra, visitors to the ESA booth #1080 will see other versatile, applications-focused systems designed to help scientists do their jobs better, faster, and easier. ESA will show a range of electrochemical cells, including the brand new ultra Analytical Cell (PittCon 2009 launch), a coulometric cell designed for use with UHPLC systems. ESA's high-efficiency, high-capacity synthesis cell will also be featured. It simplifies generation of analytes, possible degradants, or product for hard-to-make, or unavailable drug-synthesis compounds, and is ideal for producing compounds for NMR or mass spectrometry analysis or biological studies. ESA systems are easy to implement, easy to run, and easy to maintain - so scientists can spend their precious time doing research with their instruments, not on their instruments.

Pittcon attendees should be sure to stop by the ESA Knowledge Center at booth #1080. There, visitors can sit down with an ESA scientist to discuss their specific analytical challenges and customer-care needs - or peruse detailed technical presentations on a variety of applications. The company will also present 15 posters at Pittcon, listed below.

About ESA Life Science Tools (

A Magellan Biosciences business, ESA Life Science Tools enables answers to pressing analytical challenges for analytical and diagnostics laboratories worldwide. Leaders in HPLC detection, ESA's flexible, applications-focused systems combine specialty detectors with optimized components and consumables - all designed to achieve maximum performance. ESA's Customer Care experts deliver the highest standard of service to ensure customer confidence, security, knowledge, and support.

ESA Pittcon Posters

    Poster #   Topic                                  Detector     Date

    2680-8     Determination of Free and Acylated
               Glycerols in Biodiesel by HPLC-CAD     Corona       03/12/2009

    2730-26    Generic Approach to Analysis of
               Pharmaceutical Salts Including
               Inorganic and Organic Counter-ions.    Corona       03/12/2009

    600-9      Simultaneous Detection of a Broad
               Range of Compounds in Pharmaceutical
               Applications using a Single HPLC
               Detector                               Corona        03/9/2009

    2670-15    Analysis of Lipids by RP-HPLC Using
               the Corona CAD                         Corona       03/12/2009

    1630-5     The Evaluation of a New Family of
               HPLC Columns for Use with Non-UV
               Detectors                              Corona       03/10/2009

    2730-1     Novel Analytical Approaches to
               Aminoglycoside and Macrolide
               Antibiotic Determination               Corona & ECD 03/12/2009

    2730-30    Sensitive Analysis of Aminopyridine
               compounds using HPLC Electrochemical
               Detection with a Boron-Doped Diamond
               electrode                              ECD          03/12/2009

    1990-11    Determination of Lactose in Milk by
               HPLC with Corona CAD                   Corona       03/11/2009

    1600-5     Simultaneous Cation and Anion
               Analysis with Charged Aerosol
               Detection                              Corona       03/10/2009

    1600-6     Rapid Electrochemical Synthesis of
               Oxidative Metabolites for Drug
               Discovery                              ECD          03/10/2009

    2290-15    Electrochemistry On-line with LC-MS
               to Study Reactive Drug Metabolites     ECD          03/11/2009

    2290-3     Electrochemistry On-line with LC-MS to
               Produce and Characterize Drug
               Metabolites and Degradants             ECD          03/11/2009

    2730-2     High-throughput Estimation of Chemical
               Stability to Oxidative Degradation of
               Pharmaceutical Libraries Estimated by
               HPLC-CoulArray Voltammetry             ECD          03/12/2009

    2290-1     Electrochemistry On-line with LC-MS
               to Enhance Ionization and Selectivity
               of LC-MS Analysis of Small Molecules   ECD          03/11/2009

    2290-2     Use of Coulometric Array in Parallel
               with Mass Spectrometry as an
               Orthogonal Detector in Pharmaceutical
               Analysis                               ECD          03/11/2009

    Customer Posters
    600-7      Mass Balance Evaluation for Forced
               Degradation of Digitoxin Using
               HPLC-CAD (PPD)                         Corona       03/09/2009

    2970-6     Development and Validation of
               HPLC-Corona-CAD/UV Stability
               Indicating Methods (Synomics)          Corona       03/12/2009

    1630-2     Applications of Polymer-Coated C18
               Stationary Phase with Minimized
               Column Bleeding to Liquid
               Chromatography-Corona Charged
               Aerosol Detection
               (Shiseido Co., Ltd)                    Corona       03/10/2009

    1650-7     Determination of Non-chromophoric
               Small Molecule Organic Acids and
               Bases Using Corona Charged Aerosol
               Detector and Mass Spectrometry
               Coupled with Various Stationary
               Phases (Bristol Myer Squibb)           Corona       03/10/2009

    1590-4     Use of HPLC with Charged Aerosol
               Detection for Quantification of
               Biologically Relevant Oligosaccharides
               (Sacramento State University)          Corona       03/10/2009

SOURCE ESA Biosciences, Inc.
Copyright©2009 PR Newswire.
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