Navigation Links
EPHB2 as a New Potential Therapeutic Target for Mesothelioma
Date:7/31/2013

Alexandria, VA (PRWEB) July 31, 2013

Last week, the Journal of Thoracic Oncology published the results of a study looking into the overexpression of the ephrin B2 receptor (EPHB2) in patients with mesothelioma. The researchers at the New York University Langone Medical Center observed that EPHB2 is overexpressed in all malignant mesothelioma cell lines, but not in benign mesothelial cells. In addition, they found that silencing this receptor resulted in a significant increase in certain processes responsible for naturally ridding the body of old and defective cells (including cancerous ones).

The team of researchers who worked on this study includes Dr. Harvey Pass, one of the founders and a former board member of the Mesothelioma Applied Research Foundation. Dr. Pass has been a leader in the field of mesothelioma and a vocal advocate for mesothelioma patients.

“The mesothelioma community is looking for novel targets for therapy, and the data on the ephrins may provide an opportunity for this,” said Dr. Pass. “Certainly we also must expand our findings to elucidate the prognostic and predictive characteristics of this important pathway,” he added.

Through this study, Dr. Pass and his team concluded that EPHB2 could serve as a potential novel therapeutic target for treatment of mesothelioma, a disease that, currently, has only one FDA-approved treatment and a median survival of 12 months.

Mesothelioma is a malignant tumor of the lining of the lung, abdomen, or heart known to be caused by exposure to asbestos. Medical experts consider it one of the most aggressive and deadly of all cancers. Approximately 3,000 Americans are diagnosed with mesothelioma every year and an estimated one-
'/>"/>

Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Page: 1 2

Related medicine news :

1. Potential Dangers of Diet Soda Article and Video Released by Health News Wires
2. Stem cells in urine easy to isolate and have potential for numerous therapies
3. Study predicts potential surge in medically-attended injuries
4. TRICARE CRISIS: QmedRx Spotlights Potential Resolution to Budgetary Dilemma
5. Researchers find potential new target to treat malignant pleural mesothelioma
6. Monroe, CT Gum Disease Treatment Can Now Potentially Reduce the Risk of Tooth Loss with the Use of the FDA-cleared Laser by Dr. Richard Amato
7. Victory Pain Center Weighs in on Potential Risks of Steroid Injections
8. Is there a "Code" To Crack For Permanent Weight Loss? Best-Selling Author Jennifer Nicole Lee Says Yes in Her Book "Crack The Code: Unlock Your Fat Burning & Weight Loss Potential"
9. Study finds potential markers for severity of childhood arthritis
10. hCGTreatments / Diet Doc hCG Diets & Weight Loss Plans Announces New Detox Formula, Designed to Cleanse the Liver of Potentially Dangerous Toxins During Dieting
11. New Program Designed For the Best Weight Loss and Potential Reduction in Health Insurance Costs Now Available From Diet Doc hCG Diets & Weight Loss Plans / hCGTreatments
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/19/2014)... December 19, 2014 If you have ... difficulty breathing, you probably wished you had an arsenal ... COPD, cystic fibrosis, and other breathing disorders. Currently, the ... and avoiding triggers, but other common treatments do exist. ... conference in San Antonio, TX, 34 asthma educators responded ...
(Date:12/19/2014)... This is a professional and in-depth ... industry with a focus on the Chinese market. The ... the Gliquidone manufacturers and is a valuable source of ... the industry. , Firstly, the report provides a basic ... manufacturing technology. Then, the report explores the international and ...
(Date:12/19/2014)... A new study suggests a possible link between certain ... night sweats -- and higher rates of hip fractures ... menopause, affecting about 60 percent of women. The hormonal ... they then face a higher risk of weakened bones ... moderate or severe menopausal symptoms are more likely to ...
(Date:12/19/2014)... (HealthDay News) -- Traveling through the same U.S. airport ... three others within a four-hour time span, illustrating just ... shows. "The exposures in this report were not ... international terminal, highlighting the fact that measles is highly ... infectious disease specialist at the U.S. Centers for Disease ...
(Date:12/17/2014)... 2014 Dr. Myo Nwe is the co-author ... of the Future” and co-founder of the Ace Medical Weight ... Nwe takes a broad look at the industry of weight ... scientific scrutiny. On film and in television shows, however, she ... the social aspects and played for basic laughs, which she ...
Breaking Medicine News(10 mins):Health News:Harmonica Techs, Inventors of the Pulmonica®, Unveil New Findings on Complementary Treatments for Asthma 2Health News:Harmonica Techs, Inventors of the Pulmonica®, Unveil New Findings on Complementary Treatments for Asthma 3Health News:Gliquidone Industry Global and China Analysis for 2019, Now Available at ReportsnReports.com 2Health News:Gliquidone Industry Global and China Analysis for 2019, Now Available at ReportsnReports.com 3Health News:Gliquidone Industry Global and China Analysis for 2019, Now Available at ReportsnReports.com 4Health News:Gliquidone Industry Global and China Analysis for 2019, Now Available at ReportsnReports.com 5Health News:Gliquidone Industry Global and China Analysis for 2019, Now Available at ReportsnReports.com 6Health News:Severe Hot Flashes During Menopause May Raise Hip Fracture Risk Later: Study 2Health News:Arriving Now at Gate 42: Measles 2Health News:Arriving Now at Gate 42: Measles 3Health News:Obesity Should Not Be a Hollywood Punchline, Weight Loss Doc Says 2
... Ind., Jan. 20 Conseco, Inc. (NYSE: ... a stockholder rights plan,designed to protect stockholder value by ... tax net operating loss carryforwards under,Section 382 of the ... value,of those tax assets upon an "ownership change." ...
... purchased raw milk from the Conestoga Valley Dairy Farm ... to the risk of Salmonella contamination, Agriculture Secretary Dennis ... to kill disease-causing bacteria or homogenized. Pennsylvania farms selling ... samples tested in a laboratory due to the health ...
... Foundation to Host Five Cancer Fighters on January 30th ... Jan. 20 Lillians(TM), The Hippest Shoppe in Town(R) ... announced that it will postpone "the dance," its annual ... until Friday, Oct. 23, 2009, at the Medina Entertainment ...
... enterprise WLAN solution for point-of-care, voice and AeroScout asset ... Inc. (NYSE: MOT ) today announced ... LAN (WLAN) solution to support several of its current ... a 680-bed facility providing quality patient care in Montreal, ...
... other chemicals boost their odds of respiratory trouble, ... -- Frequent exposure to hospital cleaning products and ... to a U.S. study that included 3,650 Texan ... researchers found that nurses regularly exposed to cleaning ...
... MassMutual,s Retirement Services Division has added three new ... third-party administrators (TPA). The new TPA relationship managers ... investment change processing, product and service education and ... platform. Karen Buoniconti joined MassMutual,s TPA ...
Cached Medicine News:Health News:Conseco Adopts Stockholder Rights Plan 2Health News:Conseco Adopts Stockholder Rights Plan 3Health News:Conseco Adopts Stockholder Rights Plan 4Health News:Conseco Adopts Stockholder Rights Plan 5Health News:Lillians(TM) Postpones 'The Dance' Fundraising Event; New Date Is October 23, 2009 2Health News:Montreal Jewish General Hospital Improves Care and Reduces Costs With Motorola's Enterprise Mobility Solution 2Health News:Montreal Jewish General Hospital Improves Care and Reduces Costs With Motorola's Enterprise Mobility Solution 3Health News:Cleaning Products Up Nurses' Asthma Risk 2Health News:MassMutual Retirement Services Appoints Three New TPA Relationship Managers 2
(Date:12/19/2014)... 18, 2014 Radiology information ... is used to store, manipulate, and distribute patient ... patient tracking and scheduling system, result reporting, and ... with HIS and other databases improves the hospital ... patient scheduling, patient list management, radiology department workflow ...
(Date:12/19/2014)... BURLINGTON, Mass. , Dec. 18, 2014  Decision ... the United States will increase ... Growth will be primarily driven by expansion in the ... direct energy devices will be increasingly adopted due to ... launched. Other key findings from Decision Resources ...
(Date:12/19/2014)... , Dec. 18, 2014 Since last ... the site now known as the leading online black ... seen explosive growth in its offering of drugs and ... Alliance show the takedowns did succeed in lowering the ... last review of the markets in August. But some ...
Breaking Medicine Technology:The Global Radiology Information Systems Market is Expected to Grow at a CAGR of 7.5% from 2014 to 2019 2The Global Radiology Information Systems Market is Expected to Grow at a CAGR of 7.5% from 2014 to 2019 3U.S. Laparoscopic Device Market Will Reach Over $4.3 Billion by 2023 2U.S. Laparoscopic Device Market Will Reach Over $4.3 Billion by 2023 3Post Silk Road - Another Online Drug Den Now Dominates the DarkNet 2Post Silk Road - Another Online Drug Den Now Dominates the DarkNet 3
... LEUVEN, Belgium, September 29 , - Results ... ThromboGenics NV (Euronext Brussels: THR), a biotechnology company,focused ... and cancer,announces positive results from its MITI IV ... efficacy of microplasmin when administered,intravenously to acute stroke ...
... Dikembe Mutombo Foundation to improve healthcare,system in the ... Sept. 25 The Clinton Global,Initiative recognized BD ... a,leading global medical technology company, for its commitment ... system monitoring and,healthcare worker safety at the Biamba ...
Cached Medicine Technology:ThromboGenics Announces Promising Results of MITI IV Phase II Trial in the Treatment of Acute Stroke with Microplasmin 2ThromboGenics Announces Promising Results of MITI IV Phase II Trial in the Treatment of Acute Stroke with Microplasmin 3ThromboGenics Announces Promising Results of MITI IV Phase II Trial in the Treatment of Acute Stroke with Microplasmin 4Clinton Global Initiative Announces BD's Commitment to Biamba Marie Mutombo Hospital 2Clinton Global Initiative Announces BD's Commitment to Biamba Marie Mutombo Hospital 3
... (generic name: ferumoxsil) is Advanced Magnetics' oral ... loops of the bowel from other abdominal ... and tissues in the abdomen without contrast ... tissues cannot be easily distinguished from the ...
... a new Contrast Agent for ... of stabilized SF6 microbubbles. The ... between 1 and 10 m, ... 2 and 5 x 108 ...
... well-established, second-generation ultrasound medical diagnostic product with ... borders of the heart. This allows doctors ... the heart during an ultrasound scanning procedure, ... heart condition and providing guidance for the ...
... is designed for accuracy and for modularity, ... or "elbow" aimers and also between using ... tibial tunnel. The system is easy to ... reproducibility and accuracy gained from rigidity of ...
Medicine Products: