Navigation Links
EPHB2 as a New Potential Therapeutic Target for Mesothelioma
Date:7/31/2013

Alexandria, VA (PRWEB) July 31, 2013

Last week, the Journal of Thoracic Oncology published the results of a study looking into the overexpression of the ephrin B2 receptor (EPHB2) in patients with mesothelioma. The researchers at the New York University Langone Medical Center observed that EPHB2 is overexpressed in all malignant mesothelioma cell lines, but not in benign mesothelial cells. In addition, they found that silencing this receptor resulted in a significant increase in certain processes responsible for naturally ridding the body of old and defective cells (including cancerous ones).

The team of researchers who worked on this study includes Dr. Harvey Pass, one of the founders and a former board member of the Mesothelioma Applied Research Foundation. Dr. Pass has been a leader in the field of mesothelioma and a vocal advocate for mesothelioma patients.

“The mesothelioma community is looking for novel targets for therapy, and the data on the ephrins may provide an opportunity for this,” said Dr. Pass. “Certainly we also must expand our findings to elucidate the prognostic and predictive characteristics of this important pathway,” he added.

Through this study, Dr. Pass and his team concluded that EPHB2 could serve as a potential novel therapeutic target for treatment of mesothelioma, a disease that, currently, has only one FDA-approved treatment and a median survival of 12 months.

Mesothelioma is a malignant tumor of the lining of the lung, abdomen, or heart known to be caused by exposure to asbestos. Medical experts consider it one of the most aggressive and deadly of all cancers. Approximately 3,000 Americans are diagnosed with mesothelioma every year and an estimated one-third were exposed while serving in the Navy or working in Navy shipyards.

ABOUT THE MESOTHELIOMA APPLIED RESEARCH FOUNDATION
The Meso Foundation is the only 501(c)3 non-profit organization dedicated to eradicating mesothelioma and easing the suffering caused by it. The Meso Foundation actively seeks philanthropic support to fund peer-reviewed mesothelioma research; provide patient support services and education; and advocate Congress for increased federal funding for mesothelioma research. The Meso Foundation is the only non-government funder of peer reviewed scientific research to establish more effective treatments for mesothelioma and, ultimately, a cure for this rare, but extremely aggressive, cancer. To date, the Foundation has awarded over $8.2 million to research.

More information is available at http://www.curemeso.org.

Read the full story at http://www.prweb.com/releases/2013/7/prweb10985987.htm.


'/>"/>
Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Related medicine news :

1. Potential Dangers of Diet Soda Article and Video Released by Health News Wires
2. Stem cells in urine easy to isolate and have potential for numerous therapies
3. Study predicts potential surge in medically-attended injuries
4. TRICARE CRISIS: QmedRx Spotlights Potential Resolution to Budgetary Dilemma
5. Researchers find potential new target to treat malignant pleural mesothelioma
6. Monroe, CT Gum Disease Treatment Can Now Potentially Reduce the Risk of Tooth Loss with the Use of the FDA-cleared Laser by Dr. Richard Amato
7. Victory Pain Center Weighs in on Potential Risks of Steroid Injections
8. Is there a "Code" To Crack For Permanent Weight Loss? Best-Selling Author Jennifer Nicole Lee Says Yes in Her Book "Crack The Code: Unlock Your Fat Burning & Weight Loss Potential"
9. Study finds potential markers for severity of childhood arthritis
10. hCGTreatments / Diet Doc hCG Diets & Weight Loss Plans Announces New Detox Formula, Designed to Cleanse the Liver of Potentially Dangerous Toxins During Dieting
11. New Program Designed For the Best Weight Loss and Potential Reduction in Health Insurance Costs Now Available From Diet Doc hCG Diets & Weight Loss Plans / hCGTreatments
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/24/2016)... ... June 24, 2016 , ... June 19, 2016 is World Sickle Cell ... pain and the benefits of holistic treatments, Serenity Recovery Center of Marne, ... Cell Disease. , Sickle Cell Disease (SCD) is a disorder of the red blood ...
(Date:6/24/2016)... ... , ... Global law firm Greenberg Traurig, P.A. announced that 20 Florida attorneys ... peers for this recognition are considered among the top 2 percent of lawyers practicing ... members of this year’s Legal Elite Hall of Fame: Miami Shareholders Mark D. ...
(Date:6/24/2016)... ... ... of Topricin and MyPainAway Pain Relief Products, join The ‘Business for a Fair Minimum Wage’ ... 2020 and then adjusting it yearly to increase at the same rate as the median ... floor does not erode again, and make future increases more predictable. , The company is ...
(Date:6/24/2016)... ... June 24, 2016 , ... The Haute Beauty ... Barry M. Weintraub as a prominent plastic surgeon and the network’s newest partner. ... and the most handsome men, look naturally attractive. Plastic surgery should be invisible.” ...
(Date:6/24/2016)... ... June 24, 2016 , ... National recruitment firm ... sciences executive with extensive sequencing and genomics experience, as Vice President of North American ... Hill will be responsible for leading the sales team in the commercialization of the ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... Story Highlights: ... the health care industry is causing providers to review ... Deloitte offers a suite of solutions for health care ... cost optimization: labor resource analysis, revenue cycle optimization and ... outcomes and better economics ...
(Date:6/24/2016)... Dublin ... of the " Global Markets for Spectroscopy Equipment" ... This report focuses on the global ... including its applications in various applications. The report deals ... three main industries: pharmaceutical and biotechnology, food and beverage, ...
(Date:6/24/2016)... , June 24, 2016 Research and ... Market for Companion Diagnostic Tests" report to their offering. ... for Companion Diagnostics The World Market for ... personalized medicine diagnostics. Market analysis in the report includes the ... Market (In Vitro Diagnostic Kits) by Region (N. America, EU, ...
Breaking Medicine Technology: