Navigation Links
EPC secreted factors favorably impact on pancreatic islet cell cotransplantation
Date:11/25/2013

Putnam Valley, NY. (Nov. 25 2013) Pancreatic islet transplantation is a promising therapy for treating type 1 diabetes, but the majority of transplanted cells die soon after they are transplanted. Researchers interested in prolonging the life of these cells co-transplanted endothelial progenitor cells (EPCs) along with pancreatic islet cells and found that the EPCs improved the engraftment of pancreatic islet cells in mouse models, thereby favorably impacting on the cure rate and glycemic control of transplanted islets. The study will be published in a future issue of Cell Transplantation but is currently freely available on-line as an unedited early e-pub at: http://www.ingentaconnect.com/content/cog/ct/pre-prints/content-CT1021Penko

"EPCs are a promising candidate for improving outcomes in islet transplantation and their mechanisms warrant further study," said study co-author Dr. Claire Jessup of the Department of Human Physiology at the Flinders University School of Medicine in Bedford Park, Australia. "Our study indicates that EPCs or their soluble products modulate the expression of the beta cell surface molecule connexion 36 and affect glucose-stimulated insulin release."

According to the researchers, EPCs are a circulating bone-marrow cell that are able to home to sites of damaged tissue or ischemia and can participate in wound healing and rebuilding blood vessels, especially after translantation. Although EPCs have the ability to integrate into newly growing blood vessels, they can also provide humoral factors (elements in blood or other fluids) that may "recruit" other cells to impact favorably on vascular remodeling. This study planned on exploring how EPCs secreted humoral factors and how those factors may impact pancreatic islet cell gene expression and function and thus aid islet cell survival following tramnsplantat
'/>"/>

Contact: Robert Miranda
cogcomm@aol.com
Cell Transplantation Center of Excellence for Aging and Brain Repair
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Social Factors May Affect Lifespan More Than Race, Location
2. Risk factors may inform breast cancer screening
3. Study identifies possible protective blood factors against Type 2 diabetes
4. Nerve growth factors elevated in pancreatic cancer model
5. Human factors researcher pushes for safer gas fireplaces
6. Study identifies factors related to violence in veterans
7. Mount Sinai finds common factors in autism spectrum disorders, schizophrenia, and bipolar disorder
8. Gastroenterology, CGH maintain strong 2011 impact factors
9. Are cardiac risk factors linked to less blood flow to the brain?
10. Study examines characteristics, risk factors among HIV-positive persons born outside the US
11. Some Improvement in Heart Risk Factors for Americans: CDC
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... 2015 The Incredible Bulk is a revolutionary ... increase lean muscle by up to 30lbs in less than ... of HealthyandFitZone.com’s Stan Stevenson, prompting an investigative review. , “Our ... step-by-step, scientific diet formula that allows the body to pack ...
(Date:1/22/2015)... January 22, 2015 Juvent Sports ( ... the 2015 PGA Merchandise Show to bestow a Juvent ... female amateur golfer, Arlene McKitrick. The award commemorated and ... golf tournament win. She won her first amateur tournament ...
(Date:1/22/2015)... January 22, 2015 Carinsurancesavings.biz has released a ... death and dismemberment insurance . , Purchasing an accidental ... be very advantageous. This type of rider provides benefits if ... can be considered a lesser form of life insurance. ...
(Date:1/22/2015)... IsoComforter, Inc. has introduced the most innovative and ... to treat specific body parts and muscle groups. , ... to use patented cold therapy machine with the innovative IsoTube ... muscle injuries. IsoComforter has become the industry leader in ...
(Date:1/22/2015)... JJsHouse.com is a famous dress online store for ... its latest collection of wedding dresses , and launches ... is the wedding dress on your big day; the wedding ... Every bride wants to find the most suitable wedding dress. ...
Breaking Medicine News(10 mins):Health News:The Incredible Bulk: Review Examining Ben Pakulski’s Brand New Bulking Muscle Building Diet Program Released 2Health News:All-Time Leading Female Amateur Golfer Arlene McKitrick Receives Juvent Sports Achievement Award at 2015 PGA Show 2Health News:All-Time Leading Female Amateur Golfer Arlene McKitrick Receives Juvent Sports Achievement Award at 2015 PGA Show 3Health News:Accidental Death and Dismemberment Insurance Can Be Purchased at Low Prices Online 2Health News:IsoComforter Introduces Best of Class Cold Therapy Product to the Worldwide Market 2Health News:Find The Most Suitable Wedding Dress At JJsHouse.com 2
... Pulmonary Center has received a two-year $1.4 million grant ... derive stem cells and lung progenitors from patients with ... of medicine and pathology, and Gustavo Mostoslavsky, MD, PhD, ... this new grant award. Together Kotton and Mostoslavsky lead ...
... ... honored to announce that Chris Wepfer and Jackie Kirby have been chosen as the ... Showcase. This is the second consecutive year that Chris has received such honors and ... ...
... , SAN FRANCISCO, Dec. 16 Medizone International, Inc. (OTC ... Directors and the Board of Medizone New Zealand Ltd., a ... interest, agreed on December 14, 2009 to unwind the joint ... of the company,s intellectual property. Medizone International,s Chairman, Edwin ...
... , TUESDAY, Dec. 15 (HealthDay News) -- If that little ... life that you just can,t wait to have another, take a ... wait at least six months before getting pregnant again, and that ... study found that when the interval between pregnancies was less than ...
... CITY, Dec. 16 /PRNewswire-FirstCall/ - TSO3 Inc. ("TSO3") (TSX: TOS) ... reached for 3M to be the exclusive supplier and distributor ... innovator in low temperature sterilization technology for medical devices in ... cycles to reach acute care facilities through 3M,s global sales ...
... ... in the development of products that help survivors of stroke and other forms of traumatic ... their brand new device for stroke rehabilitation, the Tailwind. (Advance for Physical Therapy and Rehab ... ...
Cached Medicine News:Health News:Boston University School of Medicine's pulmonary center receives $1.4 million grant 2Health News:Medical Solutions is Proud to Announce Chris Wepfer and Jackie Kirby as the Company's Recruiter of the Year Recipients 2Health News:Medical Solutions is Proud to Announce Chris Wepfer and Jackie Kirby as the Company's Recruiter of the Year Recipients 3Health News:Medizone International, Inc. Approves Repurchase of Global Marketing Rights 2Health News:For Babies' Sake, Pregnancy Spacing Matters 2Health News:For Babies' Sake, Pregnancy Spacing Matters 3Health News:TSO3 and 3M agree to global channel partnership - 3M to begin rollout in sequential markets as regulatory clearances are received 2Health News:TSO3 and 3M agree to global channel partnership - 3M to begin rollout in sequential markets as regulatory clearances are received 3Health News:TSO3 and 3M agree to global channel partnership - 3M to begin rollout in sequential markets as regulatory clearances are received 4Health News:New Tailwind Device Improves Arm Function in Stroke Survivors with Paralysis 2
(Date:1/23/2015)... , Jan. 23, 2015 Gem Pharmaceuticals announced today ... been enrolled into the Company,s Phase 2 clinical trial. ... of Gem,s lead compound, GPX-150 (an investigational medication), in ... metastatic disease. Logo - http://photos.prnewswire.com/prnh/20150123/170966LOGO ...
(Date:1/22/2015)... , Jan. 22, 2015  BiOptix is pleased to ... as Vice President of Chemistry and Biochemistry. Scott joins the ... AstraZeneca Pharmaceuticals, and Amgen throughout the course of his ... "Scott is a nationally recognized thought leader ...
(Date:1/22/2015)... AMGN ) today announced that it will report its ... 27, 2015, after the close of the U.S. financial markets. The ... community at 2 p.m. PT. Participating in the call from Amgen ... officer, and other members of Amgen,s senior management team. ...
Breaking Medicine Technology:Gem Pharmaceuticals Announces Enrollment of Initial Patients in its Phase 2 Clinical Trial to Assess the Efficacy and Safety of GPX-150 in Sarcoma Patients 2BiOptix Expands Leadership Team with the Appointment of Dr. Scott Klakamp as Vice President of Chemistry and Biochemistry 2Amgen Announces Webcast of 2014 Fourth Quarter and Full Year Financial Results 2
... , WESTON, Mass., Nov. 9 Groundbreaking articles in ... for the first time explore, in depth, ... care providers and its potential benefits for patients. , ... Aggarwal, PhD who is a member of the prestigious ...
... HEMPSTEAD, N.Y., Nov. 9 /PRNewswire/ -- On Sept. ... workers came together to save as many lives as possible ... of those 9/11 first responders. Now he is fighting to ... McCauley was diagnosed with cancer in 2006. He has undergone ...
Cached Medicine Technology:Medicinal Use of Marijuana: Past, Present and Future...A Fresh Look by Experts in the Field 2The SCOOTER Store Surprises 9/11 First Responder & Merrick Firefighter With Power Chair 2The SCOOTER Store Surprises 9/11 First Responder & Merrick Firefighter With Power Chair 3
... Loading Units With Titanium Staples ... (Single Use Reloadable Staplers With ... ILA™ 75 single-use stapler, anastomotic ... in the resection, transection, and/or ...
... The Auto Suture™ GIA™ Reloadable Staplers ... application in abdominal, gynecological, pediatric and ... and creation of anastomosis. , ... and the SGIA™ Knifeless Stapler have ...
... The PROXIMATE ILS Staplers are anastomotic ... proper matching of instrument to lumen diameter. ... detachable anvil head to improve access and ... surgeon to control tissue compression by adjusting ...
... Staplers are anastomotic staplers available in four ... to lumen diameter. The staplers permit tissue ... improve access and ease of use. The ... compression by adjusting the height of the ...
Medicine Products: