Navigation Links
ENERCA clinical recommendations for sickle cell disease management and prevention in children
Date:5/2/2011

ENERCA is a European Network for Rare and Congenital Anaemias funded by the European Commission and coordinated by IDIBAPS - Hospital Clnic of Barcelona. Its main purpose is offering an improved public health service to medical practitioners and patients in every aspect of rare anaemias. Recently this year this network published in the American Journal of Hematology (AJH) a series of recommendations for disease management and prevention of complications of sickle cell disease (SCD) in children. With this of publication ENERCA is willing to give clinical guidance to professional medical practitioners through medical literature.

The article is divided in three main issues: Prevention of complications, treatment and therapies for acute disease. Different aspects of each issue are exposed through the text, including the recommendations and historical references about the discovery of scientific evidence related to them. The conclusions are presented in a direct and schematic style. You can read the full text article at the magazines website.

Universal neonatal screening is the only way to detect all the sickle cell disease cases, but it is only performed in the United States, England, the Netherlands, and several cities in Belgium, with selective screening targeted on "high-risk" population in France. According to the ENERCA article, newborns diagnosed with a major sickle cell syndrome should be referred to a designated pediatric sickle cell centre where the care of the baby will be organized. Parents should be informed by an expert physician or in the community by an experienced nurse counselor.

Two preventive tools are the prophylaxis with penicillin to prevent infections and transcranial Doppler scanning to identify children with an augmented risk of suffering a stroke and include them in a transfusion program. Education and psychological support, as well as a yearly checkup, will lead to a better management of the SCD.

Pain, acute chest syndrome, infections, acute anemia and stroke may complicate the course of the disease. These complications may occur together and be difficult to disentangle, a painful crisis frequently causing fever for instance. Guidance for a correct identification of the problem and a proper use of treatments is detailed in the article.

Finally, transplantation of hematopoietic stem cells from HLA-identical siblings is the only curative therapy for SCD. Ovarian tissue can be cryopreserved but it is still unclear how useful this can be in allowing future pregnancies. In conclusion, when transplantation is not an option Hydroxyurea and chronic transfusion are the main therapeutic lines. The ENERCA article discusses the correct application of treatments and some possible side effects to help professionals to define the better possible treatment for every patient.

This guideline is the first one of a series of ENERCA documents focussed on diagnosis and clinical management of sickle cell disease. The first author of the article is Dr. Mariane de Montalembert, from Hpital Necker-Enfants Malades and Universit Paris Descartes (France), who coordinated this publication. The work is part of the ENERCA Workpackage Public health issues and clinical management of patients with Sickle cell anaemia, leaded by Dr. Beatrice Gulbis, from Hpital Erasme (Brussels, Belgium).


'/>"/>

Contact: lex Argem
aargemi@clinic.ub.es
34-932-275-700
IDIBAPS - Institut d'Investigacions Biomdiques August Pi i Sunyer
Source:Eurekalert

Related medicine news :

1. Stethoscope App gives iPhone New Clinical Skills
2. Sunquest Introduces Integrated Clinical Environment Physician Portal Solution in US
3. Almac Launches New STEMS System to Transform Temperature Controlled Shipment Monitoring in Clinical Trials
4. Clinical trial underway: Miniature ultrasound device could revolutionize pain relief
5. Michael J. Fox Foundation Awards $1.1 Million For Clinical Trial of Transdermal Nicotine as Disease-Modifying Treatment For Parkinsons
6. NOVAVAX Presents Positive Clinical Results at The World Health Organization Conference, Geneva, Switzerland
7. UCLA Health System Presents: How to Successfully Implement a Clinical Portal
8. TeraMedica Launches Evercore – Clinical Enterprise Suite 5.0 Now on Linux
9. Mesothelioma Clinical Trials List Offered by IQ Mesothelioma: Search Current Mesothelioma Treatment Options
10. MedQuist Launches EHR Integration for Dictations Associated with Template-based Clinical Documentation
11. Greenway Medical Technologies Donates Electronic Health Record, Clinical Research and Revenue Cycle Solutions to Northern Kentucky University
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/20/2017)... ... September 20, 2017 , ... The ... “Humans With Vaginas.” The goal is to ignite conversation via social media and ... products. The brand has declared September “Humans with Vaginas” month, releasing a video ...
(Date:9/20/2017)... , ... September 20, 2017 , ... ... of older Americans at risk of price gouging for their prescription drugs, according ... (TSCL) . “Because Medicare isn’t negotiating on our behalf, there’s no consistency in ...
(Date:9/20/2017)... ... , ... “The Trials I Face to Receive God’s Grace”: a mesmerizing ... and goals to better one’s life through God. “The Trials I Face to Receive ... the wrong places, found a love for writing. Green feels that expressing his feelings ...
(Date:9/20/2017)... Texas (PRWEB) , ... September 20, 2017 , ... Houston, ... entire team took Friday, September 8, and Monday, September 11, off work and rolled ... Second Baptist Church before heading to local homes to start the process of rebuilding. ...
(Date:9/20/2017)... ... 2017 , ... “The Foggy Road to Moorwick”: the adventures of a young Scottish girl yearning ... author, Jeanine Liston, a busy mother of five who used her time waiting for children ... book for over twenty years. It was a way to give some meaning to ...
Breaking Medicine News(10 mins):
(Date:9/6/2017)... 6, 2017  Medical professionals are expected ... while treating their patients. Medical simulations offer ... involving patients. Simulation provides a safe method ... out procedures, refine techniques and build confidence, ... new technology, such as augmented reality, will ...
(Date:9/5/2017)... , Sept. 5, 2017  Xyntek Inc. has announced another milestone in ... new Midwest office to meet the growing demands of customer engagements regionally.  ... Xyntek's new Midwest office is located at 318 West ... ... customer engagements regionally. ...
(Date:9/1/2017)... 1, 2017  Explorers Like Us ( https://explorerslikeus.com/ ) is ... experiences — and deliver these experiences as part of Life ... feel and heal better. ... While nothing beats a walk, jog or simply ... Life Environments™ is the next best thing when getting there ...
Breaking Medicine Technology: