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ENERCA clinical recommendations for sickle cell disease management and prevention in children
Date:5/2/2011

ENERCA is a European Network for Rare and Congenital Anaemias funded by the European Commission and coordinated by IDIBAPS - Hospital Clnic of Barcelona. Its main purpose is offering an improved public health service to medical practitioners and patients in every aspect of rare anaemias. Recently this year this network published in the American Journal of Hematology (AJH) a series of recommendations for disease management and prevention of complications of sickle cell disease (SCD) in children. With this of publication ENERCA is willing to give clinical guidance to professional medical practitioners through medical literature.

The article is divided in three main issues: Prevention of complications, treatment and therapies for acute disease. Different aspects of each issue are exposed through the text, including the recommendations and historical references about the discovery of scientific evidence related to them. The conclusions are presented in a direct and schematic style. You can read the full text article at the magazines website.

Universal neonatal screening is the only way to detect all the sickle cell disease cases, but it is only performed in the United States, England, the Netherlands, and several cities in Belgium, with selective screening targeted on "high-risk" population in France. According to the ENERCA article, newborns diagnosed with a major sickle cell syndrome should be referred to a designated pediatric sickle cell centre where the care of the baby will be organized. Parents should be informed by an expert physician or in the community by an experienced nurse counselor.

Two preventive tools are the prophylaxis with penicillin to prevent infections and transcranial Doppler scanning to identify children with an augmented risk of suffering a stroke and include them in a transfusion program.
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Contact: lex Argem
aargemi@clinic.ub.es
34-932-275-700
IDIBAPS - Institut d'Investigacions Biomdiques August Pi i Sunyer
Source:Eurekalert

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