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Dysfunctional families and bad neighborhoods may worsen asthma in children and adolescents
Date:9/27/2007

A lack of family support and problems in ones neighborhood are associated with greater asthma symptoms in children and adolescents, according to researchers in Vancouver, Canada.

Social environment has long been thought to be an important factor in asthma manifestations in youth, but few studies have empirically tested social factors at the family, peer and neighborhood levels and their implications for childhood asthma.

Edith Chen, Ph.D., of the University of British Columbia, and other researchers set out to determine whether, and to what extent, social factors influence asthma symptoms and lung function. They reported their results in the first issue for October in the American Journal of Respiratory and critical care Medicine, published by the American Thoracic Society.

The researchers hypothesized that greater neighborhood problems and a lack of peer and family support would all relate to greater asthma morbidity. Furthermore, they hypothesized that social factors would work by altering either biological systems, such as inflammation, or behaviors, such as smoking.

They recruited 78 children who had physician-diagnosed asthma without other chronic illnesses, and assessed the extent to which youth perceived support from family, support from peers and problems in their neighborhood, such as crime and violence. They measured their lung function using standardized spirometry techniques, and assessed their asthma symptoms based on interviews and daily diaries that the subjects kept. They also assessed behaviors, including smoking and compliance with medications, and evaluated biological markers of inflammation including IgE, eosinophil count and IL-4 production.

The investigators found a correlation between social environment and asthma symptoms and lung function. Asthma symptoms were greater among children who reported less family support and lived in worse neighborhoods; lung function also was poorer among childre
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Contact: Keely Savoie
ksavoie@thoracic.org
212-315-8620
American Thoracic Society
Source:Eurekalert

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