Date:6/18/2008

the Anticonvulsant Screening Program at the US National Institute of Neurological Disorders and Stroke and the O'Brien group have provided deep insights and capabilities in in vivo screening in a large range of different seizure models. Associate Professor O'Brien also provides clinical insights and expertise for lead selection and clinical testing. The Program technology is protected by an expanding patent estate covering broad composition of matter and method of use patents over compound and peptide classes and assay technologies. Overall, the Program represents a unique capability to exploit the potential of Dynamin as a novel therapeutic target for epilepsy.

Approximately one in 120 people have epilepsy, while up to 5% of the world's population may have a seizure at some time in their lives. Epilepsy is diagnosed when seizures are unprovoked and recurrent. Approximately only 70% of patients with epilepsy benefit from current treatments. There is a large unmet medical need for new therapeutic approaches to help those patients that do not receive benefit from current treatments, or suffer from undue side effects.

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Contact: Jens Tampe j.tampe@bio-link.com 61-292-094-381 Research Australia Source:Eurekalert

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