Navigation Links
Dwarfism Mutation May Protect From Cancer, Diabetes
Date:2/16/2011

WEDNESDAY, Feb. 16 (HealthDay News) -- A genetic mutation that causes a type of dwarfism may also protect against cancer and diabetes, a new study finds.

The finding suggests it may be possible to use drugs or other methods to achieve similar protection in normal-height adults, said study authors Valter Longo, a University of Southern California cell biologist, and Ecuadorian endocrinologist Jaime Guevara-Aguirre.

Their research included people in a remote community on the slopes of the Andes mountains. Many members of the community have Laron syndrome, a deficiency in a gene that prevents that body from using growth hormone.

For 22 years, the researchers followed about 100 people with Laron syndrome and 1,600 of their normal-stature relatives. During that time, no one with Laron syndrome developed diabetes and only one person got cancer, while 5 percent of their relatives were diagnosed with diabetes and 17 percent with cancer.

The study appears in the Feb. 17 issue of Science Translational Medicine.

"The growth hormone receptor-deficient people don't get two of the major diseases of aging. They also have a very low incidence of stroke, but the number of deaths from stroke was too small to determine whether it's significant," Longo said in a university news release.

There are already drugs approved by the U.S. Food and Drug Administration that block growth hormone activity. Currently, those drugs are used to treat acromegaly, a condition related to gigantism.

Other research has found that caloric restriction and fasting also reduce growth hormone activity, according to the news release, although going without food and nutrients carries risks.

Overall lifespan was the same for both groups, but those with Laron syndrome died more often from substance abuse and accidents.

"Although all the growth hormone deficient subjects we met appear to be relatively happy and normal and are kn
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved

Page: 1 2

Related medicine news :

1. Method of DNA repair linked to higher likelihood of genetic mutation
2. Destined for disease: Breast cancer mutation regulates cell fate
3. Gene Mutation May Protect Blacks From Heart Disease
4. Gene Mutation Found in One of Four Cases of Deadly Brain Cancers
5. Gene Mutation Suggests New Treatment Target for Specific Lymphoma
6. New clue in leukemia mystery: Researchers identify poison employed by deadly enzyme mutations
7. Genetic mutations associated with increased PSA and prostate cancer
8. Novel genetic mutation that causes the most common form of eye cancer discovered
9. Mutations in single gene predict poor outcomes in adult leukemia
10. Gene Mutations Seem to Make a Leukemia More Deadly
11. Unexpectedly small effects of mutations in bacteria bring new perspectives
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/1/2014)... Nordic Naturals is kicking off ... cause. The campaign—“Buy One Bottle. Help Two Heroes.”—will ... a nonprofit organization that helps rebuild the lives ... that would otherwise face euthanasia. From October through ... monthly donations of Nordic Naturals omega-3s to veterans ...
(Date:10/1/2014)... Deland, Florida (PRWEB) October 01, 2014 ... to promote awareness and early detection plans while raising ... to support Breast Cancer Awareness Month in ... Water also wants to promote the importance of having ... contaminated drinking water may be linked to certain forms ...
(Date:10/1/2014)... CA (PRWEB) October 01, 2014 ... will speak to a group of dental specialists who ... the northern Spain city of Oviedo. Dr. Reshad of ... and lecturer with clients on two continents, will give ... and aesthetic full mouth reconstruction. , “These specialists want ...
(Date:10/1/2014)... 2014 Dr. Saj Jivraj, one of ... is traveling to Chennai, India, tomorrow to speak at ... and 3. , Dr. Jivraj is founder of the ... Calif., and one of the world’s foremost prosthodontists, meaning ... He is speaking to the Indian Society of Oral ...
(Date:10/1/2014)... October 01, 2014 Today marks the ... Dental Art Institute in Oxnard and Woodland Hills, Calif., ... full mouth rehabilitation training. , “Speaking to this group ... transformative procedures to get the help and care they ... involve repairing previous dental work, providing cosmetic dentistry, correcting ...
Breaking Medicine News(10 mins):Health News:Nordic Naturals® Inspires Support for Paws for Veterans -- ‘Buy One Bottle. Help Two Heroes.’ Initiative Kicks Off October 1 2Health News:Pelican Water Supports Breast Cancer Awareness Month with Order Donations 2Health News:Woodland Hills Dental Implants Expert Training Dental Specialists in Spain Later This Week 2Health News:Woodland Hills Dental Implants Expert Training Dental Specialists in Spain Later This Week 3Health News:Woodland Hills Dental Implants Expert Training Dental Specialists in Spain Later This Week 4Health News:One of Woodland Hills’ Top Cosmetic Dentists Speaking to Indian Society of Oral Implantologists Tomorrow 2Health News:One of Woodland Hills’ Top Cosmetic Dentists Speaking to Indian Society of Oral Implantologists Tomorrow 3Health News:One of Woodland Hills’ Top Cosmetic Dentists Speaking to Indian Society of Oral Implantologists Tomorrow 4Health News:One of Woodland Hills’ Top Cosmetic Dentists Speaking to Indian Society of Oral Implantologists Tomorrow 5Health News:Internationally Respected Oxnard Dentist Concludes All-on-4™ Dental Implants Training Today 2Health News:Internationally Respected Oxnard Dentist Concludes All-on-4™ Dental Implants Training Today 3Health News:Internationally Respected Oxnard Dentist Concludes All-on-4™ Dental Implants Training Today 4Health News:Internationally Respected Oxnard Dentist Concludes All-on-4™ Dental Implants Training Today 5
... 19, 2011 The Children,s Health Insurance Program Reauthorization ... health care quality measures to be identified for voluntary ... Programs (CHIP), which together cover almost 40 million American ... Pediatrics, the official journal of the American Pediatric Association, ...
... Just like intelligence agents watching for the real terrorists ... hand-washing protocols via hand-washing squads in hospitals can go ... C. diff bacteria, says Irena Kenneley, an ... nursing from the Frances Payne Bolton School of Nursing ...
... By Steven Reinberg HealthDay Reporter , THURSDAY, May ... recovery Thursday, one day after doctors inserted a plastic implant ... after she was shot in the head by a would-be ... well after her surgery today," read a Wednesday statement from ...
... the University of Miami (UM) Department of Psychology participated in ... with Autism Spectrum Disorder (ASD). The study is one of ... for preschoolers with autism. The findings are published online ... Autism Spectrum Disorders . The report concludes the ...
... HealthDay Reporter , THURSDAY, May 19 (HealthDay News) -- For ... allergy experts. "Everyone always has a reason to ... allergies," said Dr. David Rosenstreich, director of the allergy and ... But this year those complaints really do have some ...
... French . , Montreal, May 19, 2010 ... be a taxing experience marked by personal sacrifices and psychological ... and the University of British Columbia has found family caregivers ... depressive symptoms unless they refocus their priorities and lighten ...
Cached Medicine News:Health News:Important info about CHIPRA core set of recommended health care quality measures released 2Health News:Important info about CHIPRA core set of recommended health care quality measures released 3Health News:Important info about CHIPRA core set of recommended health care quality measures released 4Health News:Important info about CHIPRA core set of recommended health care quality measures released 5Health News:Combating the C. diff terrorists on the loose in hospitals 2Health News:Combating the C. diff terrorists on the loose in hospitals 3Health News:Rep. Giffords Recovering After Skull Surgery 2Health News:Rep. Giffords Recovering After Skull Surgery 3Health News:Validating preschool programs for children with autism 2Health News:Springtime and the Sneezin' Is Easy 2Health News:Springtime and the Sneezin' Is Easy 3Health News:Bearing through it: How caregivers of mentally ill kin can cope 2
(Date:10/1/2014)... October 1, 2014 Sophia ... le domaine de l,analyse des données issues du ... solution de diagnostic in vitro (IVD) du gène ... de la mucoviscidose dans un seul essai SGN. ... tous les types de variantes par l,intermédiaire d,un ...
(Date:10/1/2014)... Switzerland , October 1, 2014 ... and Next Generation Sequencing (NGS) data analysis, today launches ... full cystic fibrosis analysis in a single NGS experiment. ... of all types of variants in a single NGS ... now, it has not been possible to simultaneously analyse ...
(Date:9/30/2014)... health and safety of Canadians is our government,s highest priority.  Our ... at its disposal to help ensure that the drugs Canadians need ... end, Health Canada has taken decisive ... of all drug products from three plants in ... Pharmachem India Pvt Ltd , Apotex Research Private Limited ...
Breaking Medicine Technology:Sophia Genetics lance une analyse complète du gène CFTR dans un essai clinique SGN 2Sophia Genetics lance une analyse complète du gène CFTR dans un essai clinique SGN 3Sophia Genetics Launches Full CFTR Analysis in Single Clinical Grade NGS Experiment 2Statement by the Honourable Rona Ambrose on the import ban of drug products from three plants in India 2
... BEDFORD, Mass., Feb. 4, 2011 Hologic, Inc. ... ), a leading developer, manufacturer and supplier of ... products dedicated to serving the healthcare needs of ... Administration (FDA) has approved Hologic,s pharmaceutical named Makena™ ...
... SPRING, Md., Feb. 4, 2011 The U.S. Food ... to reduce the risk of preterm delivery before 37 ... of at least one spontaneous preterm birth.   ... is not intended for use in women with a ...
Cached Medicine Technology:FDA Approves Hologic's Makena™ (Formerly Referred to as Gestiva™) Pharmaceutical 2FDA Approves Drug to Reduce Risk of Preterm Birth in At-Risk Pregnant Women 2FDA Approves Drug to Reduce Risk of Preterm Birth in At-Risk Pregnant Women 3
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
Medicine Products: