Navigation Links
Duska Therapeutics and DSM Pharmaceuticals in Manufacturing Collaboration for PSVT Drug Product
Date:11/10/2008

Pivotal Phase 3 Clinical Trial For Duska's ATPace In Planning Stage

LA JOLLA, Calif. and PARSIPPANY, N.J., Nov. 10 /PRNewswire-FirstCall/ -- Duska Therapeutics, Inc., (OTC Bulletin Board: DSKA) and DSM Pharmaceuticals, Inc., announced today that they have entered into a preliminary agreement to collaborate on the manufacture of commercial batches of ATPace for Duska's planned pivotal Phase 3 clinical trial in paroxysmal supraventricular tachycardia (PSVT). ATPace will be produced at DSM's commercial facilities in Greenville, North Carolina.

ATPace, a stable liquid formulation of adenosine 5'-triphosphate (ATP) for intravenous injection, is an investigational drug for the acute termination of PSVT. The bradycardic effect of ATP, in particular its blockade of atrio- ventricular nodal conduction, has been shown in numerous published clinical studies to safely and effectively terminate re-entrant PSVT involving the atrio-ventricular node. Design of a pivotal Phase 3 clinical trial for ATPace in PSVT is in the planning stage.

PSVT, one of the most common cardiac arrhythmias, is a rapid, regular heart rate originating in the atria. It has been estimated that there are 89,000 new cases of PSVT per year and approximately 570,000 persons with PSVT in the United States alone.

Currently, adenosine is the only approved treatment for PSVT in the United States. Duska believes that the initial dose of ATPace will be significantly more efficacious than the initial labeled dose of adenosine in terminating PSVT. While both ATP and adenosine inhibit atrio-ventricular nodal conduction, ATP is believed to have dual inhibitory action; one mediated by adenosine, the product of its rapid enzymatic degradation, and the other a triggered vagal reflex. Vagal maneuvers aimed at enhancing vagal tone to the heart, and thereby suppressing atrio-ventricular nodal conduction, have been clinically used to terminate tachycardia. Injectable formulations of ATP have b
'/>"/>

SOURCE Duska Therapeutics, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine news :

1. Duska Therapeutics Acquires Technology for ATPotent Sperm Motility Program
2. Duska Therapeutics Receives Comments From FDA on Phase 3 ATPace(TM) Protocol Synopsis
3. Duska Therapeutics Sponsored University of Pennsylvania Study Demonstrates ATP Improves Sperm Motility and In Vitro Fertilization in Animals
4. Duska Therapeutics Plans 505(b)(2) NDA Filing Route for ATPace(TM)
5. Transition Therapeutics to Hold Conference Call on First Quarter Fiscal 2009 Financial Results on Monday, November 10th, at 4:30 P.M. EST
6. Nektar Therapeutics Repurchases $100 Million of Convertible Debt and Reports Third Quarter 2008 Financial Results
7. Cell Therapeutics, Inc. (CTI) Rodman & Renshaw Healthcare Conference Presentation to be Webcast
8. Cornerstone Therapeutics Announces New Board of Directors
9. Orexigen(R) Therapeutics Announces Webcast of Third Quarter Financial Results on November 6, 2008
10. Cornerstone BioPharma Announces Completion of Merger with Critical Therapeutics
11. Cell Therapeutics, Inc. (CTI) Oppenheimer & Co. Healthcare Conference Presentation to be Webcast
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... Bradley, Illinois (PRWEB) January 22, 2015 Deer ... -- will host a Valentine’s Day Happy Hour from 3 p.m. ... located at 12500 Regency Parkway in Huntley, Illinois, serves adults with ... Happy Hour event will include Valentine's Day treats, games and sweetheart-themed ...
(Date:1/22/2015)... Va. (PRWEB) January 22, 2015 Liberty University ... Counseling (M.A.) program from the Council for Accreditation ... program, part of Liberty’s Center for Counseling & Family ... founding dean of the university’s new School of Behavioral Sciences. ...
(Date:1/22/2015)... January 22, 2015 The City of West Hollywood ... a.m., to commemorate the 42nd anniversary of the Supreme Court decision ... “It’s been 42 years since the Roe vs. Wade decision and ... as present as ever,” said City of West Hollywood Councilmember Abbe ...
(Date:1/22/2015)... Chemo Duck Program is pleased to announce the release of the ... with cancer. The Chemo Duck App, available on iTunes for use ... to help children of all ages living with cancer adjust to ... entertained, educated and at ease while waiting for clinic visits or ...
(Date:1/22/2015)... January 23, 2015 VogueQueen is a seasoned ... prices and many designers are thrilled to have it lead ... announces its new collection of prom dresses for the global ... drive the strategic vision and he focuses on continuing the ...
Breaking Medicine News(10 mins):Health News:Deer Path of Huntley Affordable Assisted Living to Host Valentine's Day Happy Hour 2Health News:Liberty University's Resident Master’s Counseling Program Receives CACREP Accreditation 2Health News:Chemo Duck Launches First App Ever Created for Kids with Cancer 2Health News:Chemo Duck Launches First App Ever Created for Kids with Cancer 3Health News:VogueQueen Unveils New Designs of Prom Dresses for 2015 2
... Group, Inc. will provide substantial ... revenues for the company, ... American Health Resorts, Inc. (Pink Sheets:,CAHR) of Beverly Hills, California, today ... corporate note deal valued at,approximately $8 million., With Momentum Medical ...
... ... Total Debt Reduced, BIRMINGHAM, Ala., Feb. 25 HealthSouth,Corporation (NYSE: ... the fourth quarter ended December 31, 2007. Compared to the,fourth quarter ... by 4.6% and discharges increased by,0.9%., "We are pleased with ...
... 25 Lung Cancer Alliance,(LCA) cautioned today that recently ... more people each year than all the other,major cancers ... of government statistics,entitled Cancer Facts and Figures for 2008, ... been made against cancer over the,past 15 years.", ...
... ... - ANNUAL REVENUES INCREASED 34.5% ... FFO PER SHARE UP 7.8%, NEWPORT BEACH, Calif., Feb. 25 Nationwide,Health Properties, Inc. ... investment activity., "We ended 2007 on a strong note with fourth quarter revenues up ...
... COLUMBUS, Ohio Scientists have identified the role of ... in resisting certain classes of antibiotics. , The finding ... could target bacterial resistance at its cellular source. Before ... of the activities at play in the conflict between ...
... Sunrise Senior Living,Inc. (NYSE: SRZ ) ... on March 3, 2008. Management will not be ... and explanations of,variances will be included in the ... be released before markets open., About Sunrise ...
Cached Medicine News:Health News:Vital Health Technologies, Inc. / Caribbean American Health Resorts Inc. Acquires Momentum Medical Group, Inc. 2Health News:Vital Health Technologies, Inc. / Caribbean American Health Resorts Inc. Acquires Momentum Medical Group, Inc. 3Health News:Vital Health Technologies, Inc. / Caribbean American Health Resorts Inc. Acquires Momentum Medical Group, Inc. 4Health News:HealthSouth Reports Results for Fourth Quarter Ended December 31, 2007 2Health News:HealthSouth Reports Results for Fourth Quarter Ended December 31, 2007 3Health News:HealthSouth Reports Results for Fourth Quarter Ended December 31, 2007 4Health News:HealthSouth Reports Results for Fourth Quarter Ended December 31, 2007 5Health News:HealthSouth Reports Results for Fourth Quarter Ended December 31, 2007 6Health News:HealthSouth Reports Results for Fourth Quarter Ended December 31, 2007 7Health News:HealthSouth Reports Results for Fourth Quarter Ended December 31, 2007 8Health News:HealthSouth Reports Results for Fourth Quarter Ended December 31, 2007 9Health News:HealthSouth Reports Results for Fourth Quarter Ended December 31, 2007 10Health News:HealthSouth Reports Results for Fourth Quarter Ended December 31, 2007 11Health News:HealthSouth Reports Results for Fourth Quarter Ended December 31, 2007 12Health News:HealthSouth Reports Results for Fourth Quarter Ended December 31, 2007 13Health News:HealthSouth Reports Results for Fourth Quarter Ended December 31, 2007 14Health News:HealthSouth Reports Results for Fourth Quarter Ended December 31, 2007 15Health News:HealthSouth Reports Results for Fourth Quarter Ended December 31, 2007 16Health News:HealthSouth Reports Results for Fourth Quarter Ended December 31, 2007 17Health News:HealthSouth Reports Results for Fourth Quarter Ended December 31, 2007 18Health News:HealthSouth Reports Results for Fourth Quarter Ended December 31, 2007 19Health News:HealthSouth Reports Results for Fourth Quarter Ended December 31, 2007 20Health News:HealthSouth Reports Results for Fourth Quarter Ended December 31, 2007 21Health News:HealthSouth Reports Results for Fourth Quarter Ended December 31, 2007 22Health News:'Enormous Progress' in Reducing Cancer Does Not Include Lung Cancer 2Health News:NHP Reports Fourth Quarter and Full Year 2007 Earnings 2Health News:NHP Reports Fourth Quarter and Full Year 2007 Earnings 3Health News:NHP Reports Fourth Quarter and Full Year 2007 Earnings 4Health News:NHP Reports Fourth Quarter and Full Year 2007 Earnings 5Health News:NHP Reports Fourth Quarter and Full Year 2007 Earnings 6Health News:NHP Reports Fourth Quarter and Full Year 2007 Earnings 7Health News:NHP Reports Fourth Quarter and Full Year 2007 Earnings 8Health News:NHP Reports Fourth Quarter and Full Year 2007 Earnings 9Health News:NHP Reports Fourth Quarter and Full Year 2007 Earnings 10Health News:NHP Reports Fourth Quarter and Full Year 2007 Earnings 11
(Date:1/23/2015)... BIRMINGHAM, Ala. , Jan. 23, 2015 Gem ... (STS) patients have been enrolled into the Company,s Phase ... efficacy and safety of Gem,s lead compound, GPX-150 (an ... for advanced or metastatic disease. Logo - ...
(Date:1/22/2015)... BOULDER, Colo. , Jan. 22, 2015  BiOptix is ... Klakamp as Vice President of Chemistry and Biochemistry. Scott ... Takeda Pharmaceuticals, AstraZeneca Pharmaceuticals, and Amgen throughout the course ... and development. "Scott is a nationally recognized ...
(Date:1/22/2015)... AMGN ) today announced that it will report its ... 27, 2015, after the close of the U.S. financial markets. The ... community at 2 p.m. PT. Participating in the call from Amgen ... officer, and other members of Amgen,s senior management team. ...
Breaking Medicine Technology:Gem Pharmaceuticals Announces Enrollment of Initial Patients in its Phase 2 Clinical Trial to Assess the Efficacy and Safety of GPX-150 in Sarcoma Patients 2BiOptix Expands Leadership Team with the Appointment of Dr. Scott Klakamp as Vice President of Chemistry and Biochemistry 2Amgen Announces Webcast of 2014 Fourth Quarter and Full Year Financial Results 2
... Jan. 14, 2011   The Cleveland Clinic and Valence ... the Clinic,s effort to become a clinically integrated network. ... the Cleveland Clinic Hospitals, physicians, and more than 1,000 ... Clinic, through its Community Physician Partnership (CPP), recognized the ...
... 2011 New Product Planning (NPP) groups play a vital ... set the stage for a successful launch. One of the ... activities such as ad boards, and thought leader identification and ... New Product Planning: Role and Activities for Medical Affairs ...
Cached Medicine Technology:Valence Health Selected by Cleveland Clinic to Support Clinical Integration Program 2Best Practices, LLC Research Highlights Critical Role of Medical Affairs in New Product Launch Success 2
Conducting disposable tips provide cross-contaminationfree pipetting for sensitive applications such as PCR setup....
... to optimize the accuracy and precision of ... is widely recognized by customers throughout the ... over the years and now covers a ... including filter tips, certified pure tips, stepper ...
... the Finntip Wide is designed especially for ... genomic DNA. This tip eliminates the mechanical ... excellent for use with extremely viscous liquids. ... of the orifice is 1.1 mm or ...
Capillary section fits into a 0.3-mm well for accurate loading of sequencing gels...
Medicine Products: