Navigation Links
Duska Therapeutics Sponsored University of Pennsylvania Study Demonstrates ATP Improves Sperm Motility and In Vitro Fertilization in Animals
Date:5/14/2008

LA JOLLA, Calif., May 14 /PRNewswire-FirstCall/ -- Duska Therapeutics, Inc. (OTC Bulletin Board: DSKA.OB) ("Duska" or the "Company") announced today that scientists from the University of Pennsylvania's Center for Research on Reproduction and Women's Health have published the results of the Company's sponsored study showing that extracellular ATP (adenosine 5'-triphosphate) improves sperm motility and increases fertilizing capability in mice.

The data was published online in the journal Biology of Reproduction (http://www.biolreprod.org/cgi/content/abstract/biolreprod.107.065565).

The University of Pennsylvania scientists studied sperm obtained from two mouse strains: one with normal and the other one with low fertilization capacity. Extracellular ATP treatment of these sperm in vitro (outside of the body) resulted in improved sperm motility parameters and was associated with a rapid increase in the level of intracellular calcium. The effect was inhibited by two P2 receptor antagonists. Furthermore, extracellular ATP treatment of mouse sperm resulted in increased success rates of in vitro fertilization (IVF) procedures. The improved fertilization rate was much more pronounced when sperm from the mouse strain with low fertility were used.

The authors suggest that ATP's activation of P2 receptors to modulate sperm function may be beneficial for artificial reproductive techniques.

"We are extremely pleased with the positive results of sperm treatment with ATP, which were obtained in this second Duska-sponsored study," said Dr. Amir Pelleg, Duska's President and Chief Scientific Officer. "These results indicate that the mechanism of action of extracellular ATP on improving sperm motility and fertilization potency is mediated by P2 receptors and increased level of intracellular calcium. The data further support the development of ATPotent(TM
'/>"/>

SOURCE Duska Therapeutics
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine news :

1. Duska Therapeutics Plans 505(b)(2) NDA Filing Route for ATPace(TM)
2. Transition Therapeutics to Hold Conference Call on Third Quarter Fiscal 2008 Financial Results on Wednesday, May 14, 2008 at 4:30 P.M. EST
3. TorreyPines Therapeutics Reports First Quarter 2008 Financial Results and Accomplishments
4. Jane Moffitt, J.D., LL.M. Named Vice President of Regulatory Affairs of Nile Therapeutics
5. Zevalin Revenues Lead Cell Therapeutics, Inc.s First Quarter 2008 Financial Results
6. Nektar Therapeutics Announces First Quarter 2008 Results
7. TorreyPines Therapeutics Licenses Intellectual Property from Johns Hopkins Related to Novel Uses of Glutamate Receptor Antagonists for Prevention, Treatment of Stroke, Heart Attack
8. Transition Therapeutics to Present at 2008 Morgan Stanley Global Healthcare Unplugged Conference
9. Echo Therapeutics and Cato BioVentures Sign Right of First Offer Agreement for Dermatology Products and Transdermal Drug Delivery Technologies
10. CV Therapeutics to Announce 2008 First Quarter Financial Results on Friday, April 25, 2008
11. Precision Therapeutics Adds 8 Million Covered Lives Under Contract
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/22/2014)... CA (PRWEB) December 22, 2014 The ... PALS, BLS and ACLS online certification provider, are proud ... http://www.acls-pals-bls.com . The updated site now features a more ... than ever to use. , As a company ... information is now consolidated into a single page during ...
(Date:12/22/2014)... Harrisburg, NC (PRWEB) December 22, 2014 ... contain the current Ebola virus epidemic are ... by U.S. government agencies, nongovernmental organizations (NGOs) ... solutions remains ongoing, healthcare workers, emergency responders, ... advanced technologies such as the CmTP ...
(Date:12/22/2014)... 22, 2014 Physicians in China are ... the treatment of non-Hodgkin’s lymphoma (NHL), according to a ... global healthcare consulting firm. MabThera is the only biologic ... most common form of NHL. , According to Kantar ... the incidence of NHL in China has been growing ...
(Date:12/22/2014)... Explorys, the leader in big data-driven ... team: Greg Yarrington as Vice President of Operations, Adam ... as Vice President of Solutions. These new leaders are ... in 2015 to support client demand for the company’s ... and growth of its partner network. , Since ...
(Date:12/22/2014)... 2014 In recognition of Veteran’s Day, ... Hero Reward, a local organization that provides services to ... , Located on a couple hundred acres in the ... lodging, world class fishing, hunting, hiking, horseback riding, 4-wheeling, ... several years ago to support U.S. Service men and ...
Breaking Medicine News(10 mins):Health News:ACLS Online Certification Website ACLS-PALS-BLS.com Now Features a New and User-Friendly Layout 2Health News:Novel Biostatic Antimicrobial Technology From Clearstream-mPact Technology Partnership (CmTP) Offers Effective Protection Against Transmission of Ebola Virus 2Health News:Novel Biostatic Antimicrobial Technology From Clearstream-mPact Technology Partnership (CmTP) Offers Effective Protection Against Transmission of Ebola Virus 3Health News:Novel Biostatic Antimicrobial Technology From Clearstream-mPact Technology Partnership (CmTP) Offers Effective Protection Against Transmission of Ebola Virus 4Health News:Novel Biostatic Antimicrobial Technology From Clearstream-mPact Technology Partnership (CmTP) Offers Effective Protection Against Transmission of Ebola Virus 5Health News:Physicians in China See Most Significant Demand for MabThera Biosimilar 2Health News:Physicians in China See Most Significant Demand for MabThera Biosimilar 3Health News:Explorys Continues to Experience Rapid Growth, Adds Three Healthcare IT Executives to Its Leadership Team 2Health News:Explorys Continues to Experience Rapid Growth, Adds Three Healthcare IT Executives to Its Leadership Team 3Health News:Discount Labels Donates Portion of November Sales to Hero Reward Program 2
... is expanding its advanced mobile health screening services ... screening equipment and techniques in the industry, HealthYes! screens its ... aortic aneurysm, peripheral artery disease and osteoporosis. , ... ...
... & Liber LLP have been named 2009 Ohio Super Lawyers ... recognizes the law firm,s expertise in personal injury cases and as ... ... Cleveland, Ohio (PRWEB) March 4, 2009 -- Five Cleveland lawyers representing ...
... cervical cancer may direct more women to optimal ... morbidity and complications of trimodality therapy (surgery followed ... the Institute for Technology Assessment in Boston, MA. ... a decision-analytic model to determine the value of ...
... of trauma patients who undergo CT evaluation have incidental ... Corp. at Grant Medical Center in Columbus, OH. ... concern for physicians in regards to the diagnosis and ... out of 1,256 patients (18.3%) who underwent CT of ...
... York, NY (March 3, 2009) A study published in ... (AJN) found that almost 40% of nurses who were ... of misconduct between 2001 and 2005. Nurses on probation ... to recidivate, suggesting that licensing boards should carefully screen and ...
... published in the Journal of Clinical Endocrinology & ... associate professor of clinical medicine and director of the ... increasingly common with age. An estimated 37 million Americans ... of that population. Another 20 to 30 percent of ...
Cached Medicine News:Health News:HealthYes! Now Offering its Preventive Health Screening Services in Houston 2Health News:HealthYes! Now Offering its Preventive Health Screening Services in Houston 3Health News:Cleveland Attorneys Recognized as Ohio Super Lawyers 2Health News:Cleveland Attorneys Recognized as Ohio Super Lawyers 3Health News:Cleveland Attorneys Recognized as Ohio Super Lawyers 4Health News:MRI and PET/CT improve cervical cancer patient's chances for optimal treatment 2Health News:New research in AJN shows link between nurse's criminal history and professional misconduct 2Health News:New research in AJN shows link between nurse's criminal history and professional misconduct 3Health News:'Pre-diabetics' face heightened risk of heart disease 2
(Date:12/19/2014)... , Dec. 19, 2014 You,re visiting the ... and cleaning when he or she says you need ... heard before, you may have several questions and feel ... relieved to know it,s nothing to worry about. The ... questions and alleviate any anxiety the public may have ...
(Date:12/19/2014)... HILL, N.C. , Dec. 19, 2014 /PRNewswire/ ... to optimize a product,s web presence to reflect ... Brand websites, in particular, must meet the needs ... regulations and culture. According to ... more than half of the participating companies averaged ...
(Date:12/19/2014)... WORTH, Texas , December 18, 2014 /PRNewswire/ ... a networked software application/module that is used to ... related images. RIS comprises a patient tracking and ... system. The integration of RIS with HIS and ... used for patient registration and patient scheduling, patient ...
Breaking Medicine Technology:Root Canals Have Become More Routine 2Building a Best-in-Class Pharma Global Brand Website 2The Global Radiology Information Systems Market is Expected to Grow at a CAGR of 7.5% from 2014 to 2019 2The Global Radiology Information Systems Market is Expected to Grow at a CAGR of 7.5% from 2014 to 2019 3
... Pharmasset, Inc. (Nasdaq: VRUS ) announced today ... exercised their option to purchase from Pharmasset an additional ... Pharmasset after deducting the underwriting discount, from the sale ... $21.9 million. This brings the total expected net proceeds ...
... WASHINGTON, Jan. 24, 2011 More than 300 million Americans ... the flu annually. But for the 60 million people who ... pose even greater risks. Together, these respiratory diseases take a ... direct medical expenses, reducing quality of life, lowering workplace and ...
Cached Medicine Technology:Pharmasset Announces Exercise of Underwriters' Overallotment Option 2Pharmasset Announces Exercise of Underwriters' Overallotment Option 3Survey Finds Patients Oppose Prescription Mandate for OTC Medicines Containing Pseudoephedrine 2Survey Finds Patients Oppose Prescription Mandate for OTC Medicines Containing Pseudoephedrine 3Survey Finds Patients Oppose Prescription Mandate for OTC Medicines Containing Pseudoephedrine 4Survey Finds Patients Oppose Prescription Mandate for OTC Medicines Containing Pseudoephedrine 5
For the qualitative detection of cardiac troponin I (cTnl) in human whole blood and serum specimens...
For the qualitative detection of cardiac troponin I (cTnl) in human whole blood and serum specimens...
For the qualitative detection of antibodies to Treponema pallidum in human serum, plasma and whole blood specimens...
For the qualitative detection of antibodies to HIV-1 and HIV-2 in human serum, plasma and whole blood specimens...
Medicine Products: