Navigation Links
Drugs used to treat osteoporosis not linked with higher risk of esophageal cancer
Date:8/10/2010

Although some reports have suggested a link between the use of oral bisphosphonates (drugs that prevent the loss of bone mass) and esophageal cancer, analysis of medical data from more than 80,000 patients in the United Kingdom found that use of these drugs was not significantly associated with new cases of esophageal or gastric cancer, according to a study in the August 11 issue of JAMA.

Bisphosphonates are mainly used to prevent or treat osteoporosis, especially in postmenopausal women. Their use has increased dramatically in recent years in the United States and other Western populations, and are now commonly prescribed in elderly women, according to background information in the article. "Esophagitis [inflammation of the esophagus] is a known adverse effect of bisphosphonate use, and recent reports suggest a link between bisphosphonate use and esophageal cancer, but this has not been robustly investigated," the authors write. "Large studies with appropriate comparison groups, adequate follow-up, robust characterization of bisphosphonate exposure, and information on relevant confounders are required to determine whether bisphosphonates increase esophageal cancer risk."

Chris R. Cardwell, Ph.D., of Queen's University Belfast, United Kingdom, and colleagues investigated the association between bisphosphonate use and esophageal cancer by extracting data from the UK General Practice Research Database of patients treated with oral bisphosphonates, along with a group of patients not treated with these drugs (control cohort), between January 1996 and December 2006. Average follow-up time was 4.5 and 4.4 years in the bisphosphonate and control cohorts, respectively.

Excluding patients with less than 6 months follow-up, there were 41,826 members in each group (81 percent women; average age, 70.0 years). One hundred sixteen esophageal or gastric cancers (79 esophageal) occurred in the bisphosphonate cohort and 115 (72 esophageal) in
'/>"/>

Contact: Chris R. Cardwell, Ph.D.
c.cardwell@qub.ac.uk
JAMA and Archives Journals
Source:Eurekalert

Page: 1 2

Related medicine news :

1. The private sale of drugs in public hospitals
2. Social Anxiety and Panic - Alternative Treatment to Drugs and Therapy
3. Adapting to clogged airways makes common pathogen resist powerful drugs
4. Diabetes Drugs Avandia, Actos Tied to Fractures in Women
5. Drugs That Shift Cells Energy Find New Purpose
6. FDA Tightens Controls on Anemia Drugs
7. FDA Issues Warning on Key Asthma Drugs
8. Two Tulsa Pharmacies Penalized for Missing Prescription Drugs
9. Tests to Measure Safety of Anti-Clotting Drugs of Limited Value
10. Notch-blocking drugs kill brain cancer stem cells, yet multiple therapies may be needed
11. Scans Might Monitor Success of Alzheimers Drugs
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... New York (PRWEB) January 22, 2015 The ... ) in the U.S. District Court, Southern District of West ... Bard, Inc. in that proceeding’s first bellwether trial. In an ... for a new trial after finding that C.R. Bard had ...
(Date:1/22/2015)... Autocarinsurancebest.com has released a new blog post ... insurance policy . , Auto insurance quotes help many ... no longer necessary to call an agent or visit an ... on a single website: http://autocarinsurancebest.com/ . , Every business ...
(Date:1/22/2015)... York, NY (PRWEB) January 22, 2015 ... College of Sports Medicine flagship journal Medicine & ... with L-Citrulline before exercise may help reduce gastrointestinal ... exercise. 1 , Participants in the double-blind, ...
(Date:1/22/2015)... Four years since the release of their debut recording ... marriage of Avasa & Matthew Love – the duo are pleased ... release through White Swan Records on February 24, 2015. , THE ... path available to all of us to walk out of the ...
(Date:1/22/2015)... JJsHouse.com is a famous dress online store ... announces its latest collection of wedding dresses , and ... issue is the wedding dress on your big day; the ... life. Every bride wants to find the most suitable wedding ...
Breaking Medicine News(10 mins):Health News:Court Upholds $2 Million Vaginal Mesh Lawsuit Verdict Levied Against C.R. Bard in First Federal Bellwether Trial, Bernstein Liebhard LLP Reports 2Health News:Court Upholds $2 Million Vaginal Mesh Lawsuit Verdict Levied Against C.R. Bard in First Federal Bellwether Trial, Bernstein Liebhard LLP Reports 3Health News:Court Upholds $2 Million Vaginal Mesh Lawsuit Verdict Levied Against C.R. Bard in First Federal Bellwether Trial, Bernstein Liebhard LLP Reports 4Health News:Commercial Auto Insurance Provides Several Important Features! 2Health News:Study Shows Kyowa Hakko’s L-Citrulline May Help Reduce Gastrointestinal Injury During Strenuous Exercise 2Health News:Study Shows Kyowa Hakko’s L-Citrulline May Help Reduce Gastrointestinal Injury During Strenuous Exercise 3Health News:THE ROAD by Avasa & Matthew Love -- A New Album 2Health News:THE ROAD by Avasa & Matthew Love -- A New Album 3Health News:THE ROAD by Avasa & Matthew Love -- A New Album 4Health News:Find The Most Suitable Wedding Dress At JJsHouse.com 2
... ... Creativity Awards and the W3 Awards Programs, , ... (PRWEB) November 13, 2009 -- Chicago-based full-service healthcare communications ... honoring exceptional creative and interactive work. , , ,THE 39TH ANNUAL CREATIVITY AWARDS ...
... Varian, Inc. (NasdaqGS: VARI) announced today that Steady State Imaging ... SSI,s new SWIFT Software for Varian,s research MRI Systems. ... existing MR techniques with the ability to silently image structures ... , SWIFT allows the extension of MRI to high quality ...
... , SAN FRANCISCO, Nov. 12 In response to ... pandemic, State Fund has partnered with UC Berkeley,s Center ... series of free seminars statewide helping employers protect their ... and it is extremely important that business leaders educate ...
... of America, Inc. (the "REIT"), a self-managed, non-traded, real ... and Sale Agreement (the "Agreement") to acquire a medical ... $16,250,000. The closing of the acquisition is subject to ... Mary Black Medical Office Building is located on the ...
... picture of pandemic, CDC says, , THURSDAY, Nov. 12 ... come down with the H1N1 swine flu since the ... have died, including an estimated 540 children, federal health ... significant jump in the numbers of sick, hospitalized and ...
... ... P.C. has opened its new facility in Lake Success, NY. The facility will ... Epilepsy Neurologist Alan B. Ettinger, M.D., Neuro-Ophthalmologist Scott Uretsky, M.D., Neuropsychologist Gad E. ... children’s facility designed for the needs of pediatric patients. , ...
Cached Medicine News:Health News:Goble & Associates Wins Advertising Industry Awards Competitions 2Health News:Goble & Associates Wins Advertising Industry Awards Competitions 3Health News:Steady State Imaging Signs Reseller's Agreement With Varian, Inc. 2Health News:Healthcare Trust of America, Inc. Executes Agreement to Acquire a 108,500 SF Medical Office Building Located in Spartanburg, South Carolina 2Health News:22 Million Sickened by Swine Flu in 6 Months 2Health News:22 Million Sickened by Swine Flu in 6 Months 3Health News:Neurological Surgery, P.C., of Long Island, NY, Adds New Specialists and Opens New Flagship Facility in Lake Success, NY 2Health News:Neurological Surgery, P.C., of Long Island, NY, Adds New Specialists and Opens New Flagship Facility in Lake Success, NY 3
(Date:1/23/2015)... FORT MYERS, Fla. , Jan. 23, 2015  Today ... approval of Novartis, Bexsero® for the prevention of ... to 25. Bexsero and Pfizer,s vaccine Trumenba®, which received ... in helping prevent this devastating disease. ...
(Date:1/23/2015)... , Jan. 23, 2015  The Partnership to Fight Chronic Disease ... health care leaders and a new study analyzing the impact ... PFCD is a nationwide coalition working to educate policy makers and ... at the Capitol was focused on how the Iowa ...
(Date:1/23/2015)... , Jan. 23, 2015 More than a third ... quarter of those with private insurance, filled a prescription for ... a report in this week,s Morbidity and Mortality Weekly Report ... care providers to treat moderate to severe pain.  They are ...
Breaking Medicine Technology:The National Meningitis Association (NMA) Applauds FDA Approval of Second Vaccine To Protect Against Serogroup B Meningococcal Disease 2New research shows Iowa health exchange would benefit from improvements 2New research shows Iowa health exchange would benefit from improvements 3Opioid painkillers widely prescribed among reproductive age women 2Opioid painkillers widely prescribed among reproductive age women 3
... authorization for prescription medications is a time-consuming process for ... faxes and hard-copy request forms. While some on-line solutions ... solution and one that is integrated with available e-prescribing ... in the marketplace, CVS Caremark (NYSE: CVS ...
... SHENZHEN, China, May 16, 2011 /PRNewswire-Asia/ -- Global ... or the "Company"), a China-based leading vertically integrated ... and herbal cultivation businesses through its subsidiaries in ... its unaudited financial results for the first quarter ...
Cached Medicine Technology:CVS Caremark to Pilot Electronic Prior Authorization to Help Speed Patient Access to Prescription Medication 2CVS Caremark to Pilot Electronic Prior Authorization to Help Speed Patient Access to Prescription Medication 3Global Pharm Holdings Group Announces First Quarter 2011 Financial Results 2Global Pharm Holdings Group Announces First Quarter 2011 Financial Results 3Global Pharm Holdings Group Announces First Quarter 2011 Financial Results 4Global Pharm Holdings Group Announces First Quarter 2011 Financial Results 5Global Pharm Holdings Group Announces First Quarter 2011 Financial Results 6Global Pharm Holdings Group Announces First Quarter 2011 Financial Results 7Global Pharm Holdings Group Announces First Quarter 2011 Financial Results 8Global Pharm Holdings Group Announces First Quarter 2011 Financial Results 9Global Pharm Holdings Group Announces First Quarter 2011 Financial Results 10Global Pharm Holdings Group Announces First Quarter 2011 Financial Results 11
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: