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Drugmakers to End Infant Formulas of Products With Acetaminophen
Date:5/5/2011

THURSDAY, May 5 (HealthDay News) -- The makers of cold and fever medications that contain the painkiller acetaminophen said Wednesday night that they will discontinue infant-drops versions of the products to avoid confusion that might lead to overdoses, the Associated Press reported.

Once production ends, later this year, the companies will sell just one formula for all children under the age of 12. Companies such as Johnson & Johnson currently sell infant versions of the drugs (80 milligrams) that contain half the amount of acetaminophen found in regular children's formulas, the news service said.

Acetaminophen is a widely used drug found in a variety of products that helps to ease pain and reduce fever. Although it's usually safe if used according to directions, too much can damage the liver. Acetaminophen overdose is the leading cause of liver failure in the United States, with more than 50,000 people requiring emergency-room treatment each year, the AP said.

The manufacturers' announcement preceded a U.S. Food and Drug Administration meeting scheduled for later this month, at which time agency advisers will consider whether clearer instructions and safety labeling are needed for products containing acetaminophen that are marketed for children younger than 2 years of age, the news service said.

Earlier Wednesday, the FDA issued final guidance for the production, marketing and distribution of liquid over-the-counter drug products that are measured and dispensed with provided devices such as spoons, cups and droppers.

The agency developed the guidance in response to concerns about the risk of overdoses when using liquid over-the-counter (OTC) pain relievers, cold medicines, cough syrups and digestion aids if the dispensing devices included with the products have markings that are confusing, unclear or inconsistent with the dosage directions on the label.

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