Navigation Links
Drug to Prevent Preterm Labor Shows Little Benefit
Date:11/26/2008

No difference found between intensive nifedipine therapy and placebo, researchers say

WEDNESDAY, Nov. 26 (HealthDay News) -- A muscle relaxant drug widely used to prevent premature birth when women go into early labor is no more effective than a placebo at maintaining pregnancy, after the initial spell of preterm labor is stopped.

So say U.S. researchers who conducted the first ever placebo-controlled test of nifedipine and its effect on premature delivery with prolonged treatment. The study included 71 women who'd been successfully treated for preterm labor between 24 and 34 weeks of pregnancy. The women were randomly assigned to receive either nifedipine or placebo every six hours until 37 weeks of pregnancy or delivery, whichever came first.

The team found no differences between the two groups of women in terms of whether their pregnancies lasted until 37 weeks; of how long delivery was delayed; or in their babies' gestational age, birth weight and complications of prematurity. About 40 percent of women in both groups reached 37 weeks of pregnancy, with delivery delayed an average of one month.

The study is published in the December issue of the journal Obstetrics & Gynecology.

"Medication use should be minimized in pregnancy unless it's clearly indicated," lead author Dr. Deirdre Lyell, an assistant professor of obstetrics and gynecology at Stanford University School of Medicine, noted in a school news release.

Serious side effects are rare in pregnant women treated with nifedipine, she said, but even a low risk isn't worthwhile if a drug provides no benefit.

"We all want to prevent preterm birth, but prolonged treatment with nifedipine doesn't appear to be the answer," said Lyell, who believes a larger study of nifedipine is warranted.

More information

The U.S. National Institute of Child Health and Human Development has more about preterm labor and birth.



-- Robert Preidt



SOURCE: Stanford University, news release, Nov. 25, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Stanford/Packard study shows no benefit from drug widely used to prevent premature births
2. Drug Abuse and Violence Prevention Program Generates $16 Million in Potential Savings
3. US$18.5 million grant makes male circumcision a top-tier HIV prevention strategy
4. The 5-Percent Plan: Preventing Diabetes and Heart Disease
5. Heartworm Disease Prevention Protects Pets, Wallets
6. Robert Wood Johnson Foundation Announces Grant Recipients for $18 Million Dollar Initiative to Prevent Intimate Partner Violence
7. Ginkgo Biloba for Prevention of Dementia
8. Stay Upbeat, Exercise to Help Prevent Cancer in Old Age
9. Indoor Allergy Week - Cleanaer™, the New Air Purifier that Helps Prevent Spread of the Common Cold While Removing Airborne Allergen
10. Vitamin C, E Supplements Wont Help Prevent Cancer
11. Early Life Peanut Consumption Might Prevent Allergy
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Drug to Prevent Preterm Labor Shows Little Benefit
(Date:3/28/2017)... , ... March 28, 2017 , ... Usually, the impending ... daily wardrobe. However, for those self-conscious about a double chin, this means more anxiety ... ideal solution. , “For most people, a double chin is undesirable,” Dr. Goldman ...
(Date:3/28/2017)... ... March 28, 2017 , ... Qualidigm ... its corporate headquarters to a new, more expansive office space in order to ... Qualidigm purchased a distressed office building in Wethersfield, Conn. located at 936 Silas ...
(Date:3/28/2017)... ... March 28, 2017 , ... In ... Self-Funding Success website has recently developed and published an informational resource that addresses ... created based on common inquiries the site’s team of third party administrator (TPA) ...
(Date:3/28/2017)... ... 28, 2017 , ... AutismOne announced the Board Certified in ... Medicine and available for application on Saturday, May 27, 2017, following Thursday, Friday, ... Springs. , Ed Arranga, president of AutismOne, stated: "Many of the modalities termed ...
(Date:3/28/2017)... , ... March 28, 2017 , ... With expansion and ... Georgia, in early March. , The seed processing plant opened in Marshallville in 2006, ... 2016. The new office allows opportunity for transition of Patten Seed operations to the ...
Breaking Medicine News(10 mins):
(Date:3/28/2017)... CAMBRIDGE , United Kingdom and  BOSTON ... text analytics provider Linguamatics today announced ... Dow Jones . The agreement allows pharmaceutical companies ... utilizing Linguamatics I2E text mining technology. ... used by 18 of the top 20 global ...
(Date:3/28/2017)... 28, 2017  AcelRx Pharmaceuticals, Inc. (Nasdaq: ACRX), ... and commercialization of innovative therapies for the treatment ... Medicines Agency (EMA) has notified the company that ... Authorisation Application (MAA) has passed validation, and that ... The MAA for ARX-04 (known as DSUVIA™ in ...
(Date:3/28/2017)... -- The global flow cytometry market ... 2025, according to a new study by Grand View ... cancer is expected to upsurge the demand for flow ... years. In addition, higher number of physicians is inclined ... therapy, due to adverse effects caused by chemotherapy & ...
Breaking Medicine Technology: