Navigation Links
Drug to Prevent Preterm Labor Shows Little Benefit
Date:11/26/2008

No difference found between intensive nifedipine therapy and placebo, researchers say

WEDNESDAY, Nov. 26 (HealthDay News) -- A muscle relaxant drug widely used to prevent premature birth when women go into early labor is no more effective than a placebo at maintaining pregnancy, after the initial spell of preterm labor is stopped.

So say U.S. researchers who conducted the first ever placebo-controlled test of nifedipine and its effect on premature delivery with prolonged treatment. The study included 71 women who'd been successfully treated for preterm labor between 24 and 34 weeks of pregnancy. The women were randomly assigned to receive either nifedipine or placebo every six hours until 37 weeks of pregnancy or delivery, whichever came first.

The team found no differences between the two groups of women in terms of whether their pregnancies lasted until 37 weeks; of how long delivery was delayed; or in their babies' gestational age, birth weight and complications of prematurity. About 40 percent of women in both groups reached 37 weeks of pregnancy, with delivery delayed an average of one month.

The study is published in the December issue of the journal Obstetrics & Gynecology.

"Medication use should be minimized in pregnancy unless it's clearly indicated," lead author Dr. Deirdre Lyell, an assistant professor of obstetrics and gynecology at Stanford University School of Medicine, noted in a school news release.

Serious side effects are rare in pregnant women treated with nifedipine, she said, but even a low risk isn't worthwhile if a drug provides no benefit.

"We all want to prevent preterm birth, but prolonged treatment with nifedipine doesn't appear to be the answer," said Lyell, who believes a larger study of nifedipine is warranted.

More information

The U.S. National Institute of Child Health and Human Development has more about preterm labor and birth.



-- Robert Preidt



SOURCE: Stanford University, news release, Nov. 25, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Stanford/Packard study shows no benefit from drug widely used to prevent premature births
2. Drug Abuse and Violence Prevention Program Generates $16 Million in Potential Savings
3. US$18.5 million grant makes male circumcision a top-tier HIV prevention strategy
4. The 5-Percent Plan: Preventing Diabetes and Heart Disease
5. Heartworm Disease Prevention Protects Pets, Wallets
6. Robert Wood Johnson Foundation Announces Grant Recipients for $18 Million Dollar Initiative to Prevent Intimate Partner Violence
7. Ginkgo Biloba for Prevention of Dementia
8. Stay Upbeat, Exercise to Help Prevent Cancer in Old Age
9. Indoor Allergy Week - Cleanaer™, the New Air Purifier that Helps Prevent Spread of the Common Cold While Removing Airborne Allergen
10. Vitamin C, E Supplements Wont Help Prevent Cancer
11. Early Life Peanut Consumption Might Prevent Allergy
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Drug to Prevent Preterm Labor Shows Little Benefit
(Date:10/12/2017)... ... October 12, 2017 , ... CitiDent and San ... using cutting-edge Oventus O2Vent technology. As many as 18 million Americans are ... cessation in breathing. Oral appliances can offer significant relief to about 75 percent ...
(Date:10/12/2017)... , ... October 12, 2017 , ... ... to meet the demand of today’s consumer and regulatory authorities worldwide. From Children’s ... experts and tested to meet the highest standard. , These products are ...
(Date:10/12/2017)... (PRWEB) , ... October 12, 2017 , ... The American ... Excellence to Carol Friedman, PhD, FACMI, during the Opening Session of AMIA’s Annual Symposium ... 8. , In honor of Morris F. Collen, a pioneer in the field of ...
(Date:10/12/2017)... Maryland (PRWEB) , ... October 12, 2017 , ... ... magnetic drug delivery system that we intend to develop to enable prevention of ... can lead to severe hearing loss, especially in pediatric patients. For cisplatin, hearing ...
(Date:10/12/2017)... ... October 12, 2017 , ... HMP , a leader in healthcare events ... Magazine Eddie Digital Award for ‘Best B-to-B Healthcare Website.’ Winners were announced during the ... The annual award competition recognizes editorial and design excellence across a range of sectors. ...
Breaking Medicine News(10 mins):
(Date:10/10/2017)... 2017  NDS received FDA 510(k) clearance in May 2017 for ... stand specifically designed for endoscopy environments. An innovative secondary monitor solution, ... solution to support the improvement of patient outcomes, procedural efficiency, and ... ... ...
(Date:10/7/2017)... , Oct. 6, 2017   Provista, ... more than $100 billion in purchasing power, today announced ... and information. The Newsroom is the online ... industry trends, infographics, expert bios, news releases, slideshows and ... access to a wealth of resources at their fingertips, ...
(Date:10/4/2017)... Oct. 4, 2017  South Korean-based healthcare product Development ... aide "cprCUBE" on Kickstarter. The device will educate the ... arrests with better efficiency compared to the dated and ... feedback on efficacy of the compression for a more ... a goal to raise $5,000. ...
Breaking Medicine Technology: