Navigation Links
Drug therapy offers high cure rate for 2 hepatitis C subtypes
Date:4/24/2013

RON, either did not respond to interferon, could not tolerate it or were unwilling to use it, despite the fact that there were no other treatment options available to them.

"This new treatment represents a paradigm shift in the way that hepatitis C is going to be treated," says Dr. Jacobson. "We are achieving the same or higher cure rates in many patients with sofosbuvir, compared to interferon, and we are doing it in half the time with a drug that has a remarkable safety profile."

Dr. Jacobson estimates that up to half of patients with hepatitis C infection either can't use interferon or don't want to use it. "Sofosbuvir is an extremely promising treatment for this population. It is widely hoped that combinations of potent antiviral drugs will eventually replace the use of interferon, in general, for most hepatitis C patients."

The drug sofosbuvir works by interfering with the ability of the hepatitis C virus to replicate. The drug also confers a high barrier to developing the complication of drug resistance. The U.S. Food and Drug Administration (FDA) has not yet approved sofosbuvir. However, results of the four clinical trials published in the NEJM were used to support the regulatory filing submitted to the FDA by the drug's developer, Gilead Sciences, Inc.

No Treatment Options for Many Patients

Approximately 170 million people are infected with hepatitis C worldwide and 350,000 people die each year from the disease. According to federal statistics, there are an estimated four million people in the U.S. infected with hepatitis C. As there are often no symptoms, most people with hepatitis C are unaware that they are infected.

When left untreated, hepatitis C virus can cause progressive liver disease such as cirrhosis, liver cancer and liver failure. The virus is spread by contact with infected blood, such as through blood transfusions, injection drug use or sexual contact.

There are seven maj
'/>"/>

Contact: Lauren Woods
law2014@med.cornell.edu
646-317-7401
Weill Cornell Medical College
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. Epoxide hydrolase inhibition and Thiazolidinediones: A therapy for cardiometabolic syndrome
2. Palliative radiotherapy for bone metastases in elderly patients improves quality of life
3. Physical Therapy Exercises
4. How “Post Rehab Essentials” Helps People Learn About Post Rehab – V kool
5. Intensity modulated radiotherapy reduces side effects in patients with early breast cancer
6. New radiotherapy approach reduces symptoms of dry mouth in patients with head and neck cancers
7. 2 landmark studies report on success of using image-guided brachytherapy to treat cervical cancer
8. Early cognitive behavioural therapy reduces risk of psychosis
9. Nutrient Therapy Wont Help ICU Patients: Study
10. New drug combination therapy developed to treat leukemia
11. Mindfulness therapy might help veterans with combat-related post-traumatic stress disorder
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/18/2014)... 2014 PlatinumCode, a leading manufacturer ... products for the healthcare industry, announced earlier this ... percent of their profits of the sale of ... making the announcement, PlatinumCode has launched various marketing ... clinical and hospital labs with their popular “Pink ...
(Date:9/18/2014)... 2014 “Awesome” is the way Emily ... Accepting Responsibility Today) Internship Program at ARDX ( http://www.ardx.net ... describe the program as “Inspirational” and “Life-changing,” respectively. ... what they would be doing during their summer internship. ... runs and other mindless tasks,” but, instead she was ...
(Date:9/18/2014)... HealthDay Reporter WEDNESDAY, Sept. 17, 2014 ... post-traumatic stress disorder symptoms are almost three times more likely ... The findings don,t prove a direct link between ... it,s also possible that certain women are prone to food ... the research seems to add to existing evidence connecting PTSD ...
(Date:9/18/2014)... 2014 Fit Body Boot Camp , ... business in the country and its popularity, as both a ... grow enormously in 2014. , The company’s annual business ... place in Costa Mesa, CA on September 26 and 27, ... yet. Founder Bedros Keuilian, who is also considered the leading ...
(Date:9/18/2014)... September 18, 2014 It is ... important role when building a successful brand or ... review website, has recently compared plenty of professional ... http://www.best-cheap-hosting-usa.com/go/GreenGeeks/ ), Arvixe and iPage are the best ... the importance of web hosting. All-sized businesses or ...
Breaking Medicine News(10 mins):Health News:PlatinumCode Commits to Donating Five Percent of Profits from the sale of Pink Products to Support Breast Cancer Awareness 2Health News:ARDX Internship Helps Students to START on the Right Business Path 2Health News:ARDX Internship Helps Students to START on the Right Business Path 3Health News:ARDX Internship Helps Students to START on the Right Business Path 4Health News:PTSD Link to Food Addiction Seen in Report 2Health News:PTSD Link to Food Addiction Seen in Report 3Health News:With Fit Body Boot Camp World Conference Nearing, Founder Explains the Fitness Boot Camp Franchise’s Success 2Health News:With Fit Body Boot Camp World Conference Nearing, Founder Explains the Fitness Boot Camp Franchise’s Success 3Health News:Best Cheap Hosting USA: GreenGeeks, Arvixe And iPage Are The Best Hosting Suppliers In 2014 2
... study reported in the February issue of Archives of ... individuals with severe mental// illnesses are significantly more likely ... not cancer, than those without mental illnesses. ... mental illnesses, according to background information in the article. ...
... death say they are more prepared than other doctors to ... is considered futile,// reveals research published ahead of print in ... Childhood. ,The findings are based on an ... sick newborns (neonatologists) across Australia and New Zealand. ...
... the country worst hit by the flu pandemic, has stopped ... H5N1 bird flu with foreign laboratories last// month. ... efforts to fight the highly pathogenic illness and to protect ... with Baxter International. ,The H5N1 virus has ...
... Research Center, Seattle, and colleagues have come out with findings ... blood is not that positively correlated with reduced risks of ... have reported that the mineral is associated with reducing the ... the immune system. ,Over half a million ...
... fifth deadliest disease in the United States and a ... chiropractic adjustments might be// able to make a valuable ... help diabetes sufferers. ,A study published in ... positive response to chiropractic when used as part of ...
... odourless and tasteless chemical element - could help treat ... with chronic obstructive pulmonary disease (COPD) have difficulty breathing ... at the end of each breath. This has been ... shortness of breath experienced by these patients, reported health ...
Cached Medicine News:Health News:Mentally Ill Have High Risk Of Cardiovascular Death 2Health News:Doctors’ Own Fear of Death Linked to Hastening Death of Very Sick Newborn 2Health News:Higher Serum Selenium Linked With Reduced Risks of Prostate Cancer - in Some Men 2Health News:Research Explores Chiropractic's Effect on Diabetes 2Health News:Helium Helps COPD Sufferers to Exercise 2
(Date:9/17/2014)... , Sept. 17, 2014 BRIC ... Summary GlobalData,s new report, "BRIC ... market data on the BRIC Gynecological Devices market. ... dollars, volume (in units) and average prices (in ... Devices (Transcervical Sterilization Devices (Micro-inserts) and Mechanical Sterilization ...
(Date:9/17/2014)... , Sept. 17, 2014 The ... the last decade due to the recession, ... and technological advancements. This BCC Research report ... segments of the ambulance and emergency medical ... blood and hemorrhage control devices, equipment used ...
(Date:9/17/2014)... 17, 2014 Pomerantz LLP is investigating claims ... BioPharma" or the "Company") (NASDAQ: PDLI).  Such investors are ... rswilloughby@pomlaw.com or 888-476-6529, ext. 237. ... its officers and/or directors have violated Sections 10(b) and ... On September 17, 2014, the Company announced ...
Breaking Medicine Technology:BRIC Gynecological Devices Market Outlook to 2020 2BRIC Gynecological Devices Market Outlook to 2020 3Ambulance and Emergency Equipment: Global Markets 2Ambulance and Emergency Equipment: Global Markets 3Ambulance and Emergency Equipment: Global Markets 4SHAREHOLDER ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of PDL BioPharma, Inc. - PDLI 2
... Valeant Pharmaceuticals International, Inc. (NYSE: VRX ... subsidiaries, Valeant Pharmaceuticals North America LLC (VPNA) and ... agreement to acquire the assets of the Ortho ... pay Janssen $345 million for the assets, which ...
... Inc. (Nasdaq: CPIX ) announced today that ... market closes on Thursday, August 4, 2011.  A conference call ... 4, 2011, at 5:00 p.m. Eastern Time to discuss the ... 877-303-1298 (for U.S. callers) or 253-237-1032 (for international callers).  A ...
Cached Medicine Technology:Valeant Pharmaceuticals Agrees to Acquire Ortho Dermatologics 2Valeant Pharmaceuticals Agrees to Acquire Ortho Dermatologics 3
... centrifuges -- the world's most popular Microhematocrit ... one reliable, quiet, compact unit. It is ... separate centrifuges!, For your microcentrifuge needs, order ... you with the MicroMB centrifuge, microcentrifuge rotor ...
... spins up to 25,000 x g for quick and ... ease of use. The Model 5417 C is designed ... cold room and can accommodate a variety of microcentrifuge ... Spin up to 16,400 rpm; 25,000 x g ...
... The Model EXD explosion-proof laboratory floor model ... explosion-proof apparatus. EXD is suitable for use ... all divisions; "atmospheres containing gasoline, petroleum, naphtha, ... Adherence to these specifications is so strict ...
... Oven/Shaker rigidly controls the temperature and ... hybridization and washing steps. This facilitates ... nucleic acids and proteins immobilized on ... radioactive and nonradioactive labeling systems supplied ...
Medicine Products: