Navigation Links
Drug that targets vasculature growth attacks aggressive thyroid cancer
Date:5/15/2009

ORLANDO - A medication that helps stop the growth of new blood vessels has produced dramatic benefits for some patients with aggressive thyroid cancer, research from Mayo Clinic indicates.

At the annual meeting of the American Society of Clinical Oncology (ASCO), Mayo investigators report that cancer in about two-thirds of 37 patients with aggressive differentiated thyroid cancer treated with the drug pazopanib either stopped growing, or quickly shrank.

The patient responses seen to date are promising, the researchers say, because all patients had fast-growing cancers that had spread to their lungs, with half involving lymph nodes and 39 percent also involving bones.

"The benefits were striking in many patients to a degree we have not previously seen in thyroid cancer in response to other therapies, including the standard treatment of radioiodine," says Keith Bible, M.D., Ph.D., a medical oncologist and researcher who led the multicenter clinical trial funded by the National Cancer Institute. Most of the patients treated were enrolled at the Mayo Clinic campuses in Minnesota and Florida.

Approximately one-third of patients achieved sustained and dramatic benefit from pazopanib, while another one-third experienced stabilization of their cancer or some tumor shrinkage. The remaining one-third of patients did not benefit from the drug. The agent was also well tolerated by the majority of patients, Dr. Bible adds.

What is not yet known, however, is the drug's effect on overall survival. "We need more time to establish that definitively," says Dr. Bible. "The trial has been going on for just over a year, and some of our patients are still maintaining a response, while others have not been in the study long enough for us to confirm duration of response." He notes that of the 37 original t
'/>"/>

Contact: Karl Oestreich
newsbureau@mayo.edu
507-284-5005
Mayo Clinic
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. New Federal Legislation Targets Toxic Chemicals in Baby Bath Products
2. Chinese Pharma Market Continues to Grow at a 5-7% Rate in 2009; AMDL Remains on Track to Meet FY09 Financial Targets
3. AMDL, Inc. Reports 2008 Year End Financial Results and Fiscal Year 2009 Financial Targets
4. Biotech company cofounded by BIDMC scientists targets natural killer T-cells
5. Stimulus Spending Targets Modernization of the Nation's Research Infrastructure
6. Waters and LabVantage Partnership Targets Laboratory Informatics Integration to Maximize Data Management and Quality of Work
7. Scientists Discover New Drug Targets for Crohns Disease
8. New bubble targets only cancer cells
9. OHSU vaccine research targets HIV in the slower, early stage of infection
10. Nanoparticle smart bomb targets drug delivery to cancer cells
11. NHHF Scholarship Program Targets Growing Demand for Diversity Among Health Care Professionals
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2014)... identify themselves as ,old, feel worse about their own ... value than younger age groups. , New research from ... and ill, across different countries: social status, age identification ... European Social Survey. Respondents, who were all aged 70 ... researchers found that those living in societies where older ...
(Date:8/28/2014)... New York (PRWEB) August 28, 2014 ... currently perceived with great interest among other healthcare industry ... to the high demand in vaccine with respect to ... highly in demand due to an improved understanding for ... across the United States. It has led to new ...
(Date:8/28/2014)... August 28, 2014 After more than ... Vitenas is excited to announce the opening of ... kind in any city, Mirror Mirror Beauty Boutique offers ... Situated on the corner of Richmond and Drexel near ... luxurious amenities, and cutting-edge technology in a private, easy ...
(Date:8/28/2014)... By Steven Reinberg ... -- Treating pre-cancerous skin spots with a type of light ... freezing the lesions with liquid nitrogen, a new study suggests. ... on the scalp and face of people with fair complexions ... review of prior research found that people who underwent the ...
(Date:8/28/2014)... Lansdale, pA (PRWEB) August 28, 2014 ... is now available throughout the world, with large ... such services. Since laboratories differ with regard to ... times, and costs, payers may struggle to find ... testing needs. To help clients sort through these ...
Breaking Medicine News(10 mins):Health News:U.S. Vaccine Market: Opportunities and Threats by Transparency Market Research 2Health News:U.S. Vaccine Market: Opportunities and Threats by Transparency Market Research 3Health News:Mirror Mirror Beauty Boutique to Welcome Its First Patients 2Health News: Light Therapy a Good Option for Pre-Cancerous Skin Lesions, Study Says 2Health News: Light Therapy a Good Option for Pre-Cancerous Skin Lesions, Study Says 3Health News:Hayes, Inc. Unveils Laboratory Comparison Tables for GTE Clients 2
... On the third anniversary,of Hurricane Katrina, with ... America,s Health (TFAH) issued the following statement, along,with ... to major,emergencies. TFAH also provides a set of ... the next potential health emergency based on,TFAH,s annual ...
... SEATTLE, Aug. 29 Attorneys representing consumers in ... illegally rigging the price of,virtually every prescription drug ... preparing for a trial set for December 1 ... http://www.newscom.com/cgi-bin/prnh/20080317/AQM144LOGO ), Attorney Steve W. Berman filed ...
... that Obama failed to address the issue, ... Convention Wednesday night, Former President Bill Clinton called,for ... in the,United States. In praising Presidential nominee Barack ... nation,s commendable global leadership in,an area in which ...
... normal development, mouse study finds , , FRIDAY, Aug. 29 (HealthDay ... short period in early pregnancy may cause fetal problems, suggest ... initial signs of fetal alcohol syndrome, which affects one in ... high upper lip, small eye openings, and a short nose. ...
... BRISBANE, Calif., Aug. 29 InterMune, Inc.,(Nasdaq: ITMN ... and,President of InterMune, will present at the Thomas Weisel ... 10:55 a.m. EDT., To access a live audio ... log on to the investor relations page of InterMune,s,corporate ...
... MYA Cosmetic Surgery Seems to be the Provider of Choice ... Will be Next?, Months of constant cameras, mirrors all ... can have a major impact on how you feel,about the ... has,become a reality. Upon leaving the house contestants may undoubtedly ...
Cached Medicine News:Health News:On the Third Anniversary of Hurricane Katrina; Trust for America's Health Questions State of National Emergency Preparedness 2Health News:On the Third Anniversary of Hurricane Katrina; Trust for America's Health Questions State of National Emergency Preparedness 3Health News:On the Third Anniversary of Hurricane Katrina; Trust for America's Health Questions State of National Emergency Preparedness 4Health News:Hagens Berman Sobol Shapiro: Attorneys Representing Consumers Prepare for $12 Billion RICO Trial Against McKesson for Alleged Drug Price Manipulation 2Health News:Hagens Berman Sobol Shapiro: Attorneys Representing Consumers Prepare for $12 Billion RICO Trial Against McKesson for Alleged Drug Price Manipulation 3Health News:Bill Clinton and Other Leaders Call For 'Renewal of Battle Against AIDS' in the United States at Democratic Convention 2Health News:Bill Clinton and Other Leaders Call For 'Renewal of Battle Against AIDS' in the United States at Democratic Convention 3Health News:Alcohol in Early Pregnancy May Prompt Fetal Cell Death 2Health News:MYA Makes Big Brother Stars Amazing! 2Health News:MYA Makes Big Brother Stars Amazing! 3
(Date:8/28/2014)... /PRNewswire-iReach/ -- Gateway Analytical announced today that they ... Annual Global Pharma Manufacturing Summit in ... The Global Pharma Manufacturing Summit offers a networking ... biologic pharmaceutical manufacturing. The conference is focused on ... such as the increasing pressure to grow and ...
(Date:8/28/2014)... Telik, Inc. (OTCQB: TELK), a clinical ... MabVax Therapeutics, Inc. on July 8, 2014, announced ... the development of its lead antibody program designated ... Company,s internally developed antibody discovery platform.  These preclinical ... based therapeutic and diagnostic products based on this ...
(Date:8/28/2014)... 2014  Rx Safes, Inc., the manufacturer of fingerprint ... waging a new war on drugs to reduce prescription ... More than 2,500 children a day experiment with ... are easily accessed from unsecured medicine cabinets, closets and drawers. ... streets, Rx Safes will address the new age drug ...
Breaking Medicine Technology:Gateway Analytical to Promote Particulate Identification Services at the 9th Annual Global Pharma Manufacturing Summit 2Gateway Analytical to Promote Particulate Identification Services at the 9th Annual Global Pharma Manufacturing Summit 3Telik Reports Progress Toward Multiple Early Stage Milestones in the Development of a Novel Antibody-based Therapeutic Agent for Gastrointestinal Cancers 2Telik Reports Progress Toward Multiple Early Stage Milestones in the Development of a Novel Antibody-based Therapeutic Agent for Gastrointestinal Cancers 3Telik Reports Progress Toward Multiple Early Stage Milestones in the Development of a Novel Antibody-based Therapeutic Agent for Gastrointestinal Cancers 4Rx Safes, Inc. Announces New War On Drugs 2
... Study of Zalutumumab in Combination, With Radiotherapy ... COPENHAGEN, June 24 Genmab A/S (OMX: GEN),announced ... zalutumumab,(HuMax-EGFr(TM)) in combination with radiotherapy for the treatment of,advanced ... maximum of 36,patients who are ineligible for platinum based ...
... New Recommendations Address Presurgery and Pediatric Dilemmas, ... evidence-based guidelines,address the prevention and management of ... related to the routine use of,preventive therapies. ... issue of CHEST,the peer-reviewed journal of the ...
Cached Medicine Technology:Genmab Initiates Study of Zalutumumab With Radiotherapy in Head and Neck Cancer 2Genmab Initiates Study of Zalutumumab With Radiotherapy in Head and Neck Cancer 3Thrombosis Guidelines Emphasize Difficult Choices for Pregnant Women 2Thrombosis Guidelines Emphasize Difficult Choices for Pregnant Women 3Thrombosis Guidelines Emphasize Difficult Choices for Pregnant Women 4
BETADINE Solution Swab Aid antiseptic pads are for quick and easy skin degerming. Individually wrapped pads, saturated with 10% povidone-iodine solution, offer the advantages of BETADINE Solution in ...
IV Prep Swab Sticks are effective, easy to apply, dries quickly and reduces bacterial contaminations. They are ideal for preparation of the skin prior to a ventipuncture or injection....
BD Persist Plus protective barrier provides a one-step antimicrobial barrier with minimum of 1% chlorhexidine with Up to 7-day antimicrobial effectiveness....
BD Persist Plus protective barrier provides a one-step antimicrobial barrier with minimum of 1% chlorhexidine with Up to 7-day antimicrobial effectiveness....
Medicine Products: