Navigation Links
Drug shows promise for Huntington's disease
Date:2/8/2010

An early stage clinical trial of the experimental drug dimebon (latrepirdine) in people with Huntington's disease appears to be safe and may improve cognition. That is the conclusion of a study published today in the Archives of Neurology.

"This is the first clinical trial that has focused on what is perhaps the most disabling aspect of the disease," said University of Rochester Medical Center neurologist Karl Kieburtz, M.D., the lead author of the study. "While more investigation needs to be done, these results are encouraging and show, for the first time, a statistically significant benefit in terms of improved cognitive function in patients with Huntington's disease."

Huntington's disease is a progressive neurodegenerative disorder that impacts movement, behavior, cognition, and generally results in death within 20 years of the disease's onset. The disease steadily erodes a person's memory and their ability to think and learn. Over time, this cognitive impairment contributes to the loss of the ability to work and perform the activities of daily life. There are no treatments current available that effectively alter the course of the disease or improve cognition.

It is believed that mitochondria the part of the cell that helps convert food to energy plays a role in the development of Huntington's disease. Lampridine stabilizes and enhances mitochondrial function, a result that has been shown to improve behavioral, cognitive, and functional outcomes in Alzheimer's disease. Scientists speculate that this may have the same effect in patients with Huntington's disease.

The investigators studied the impact of the drug on 91 patients over a 90 day period. Half were given the drug and the other half a placebo. The patients were then evaluated using a cognitive tool called the Mini-Mental State Examination. This exam which is used by clinicians to evaluate the stage and severity of dementia and Alzheimer's
'/>"/>

Contact: Mark Michaud
mark_michaud@urmc.rochester.edu
585-273-4790
University of Rochester Medical Center
Source:Eurekalert

Page: 1 2

Related medicine news :

1. New Study Shows Nearly One Third of Overweight Adolescents See Themselves as Underweight or About Right
2. Blacks with MS have more severe symptoms, decline faster than whites, new study shows
3. Herbals Not the Answer for Asthma, Study Shows
4. New Research Shows Genes of Pregnant Women and Their Fetuses Can Increase the Risk of Preterm Labor
5. Experimental stem cell treatment arrests acute lung injury in mice, study shows
6. Violence is part of the job say nurses as study shows only 1 in 6 incidents are reported
7. A Study by Celibre Medical Corporation Shows Botox Injections to be the Most Desirable Cosmetic Procedure in Southern California
8. Diabetes patients rank health concerns differently than their doctors, U-M survey shows
9. Fear of Frailty: Research Shows Lack of Activity Threatens Seniors' Independence
10. New study shows effectiveness of MEND program in prevention and treatment of pediatric obesity
11. More smokers kick the habit with extended nicotine patch therapy, Penn research shows
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/21/2014)... 21, 2014 The employees of ... in Washington Crossing, Pennsylvania on Thursday, August 7th to ... have been looking for different ways that Pharmica could ... Partner with Pharmica Consulting. “When we heard that we ... history, we jumped at the opportunity.” , Pharmica spent ...
(Date:8/21/2014)... Teen substance abuse is long been a ... rising numbers of young adults falling victim to a drug ... difference in the community, the new Troubled Teens Boca Raton ... seeking to overcome something like teenage alcohol abuse . ... find the best teen recovery facility to focus on achieving ...
(Date:8/21/2014)... Recently nominated as the Women’s Radio Network’s “Top Host”, KC ... man he is today. Growing up, KC was greatly influenced ... women, respecting them as professionals and individuals. Through his struggles to ... man who he had the pleasure of working very closely to ... will ring a bell to most of you who, like many ...
(Date:8/20/2014)... Most people think of donating food ... get overlooked for a variety of reasons—thus making these ... Understanding this need, Dr. Bryne Willey of AlignLife ... care center, wanted to heighten awareness of the need ... annual Thanksgiving in July food drive to collect non-perishable ...
(Date:8/20/2014)... 2014 Medical Alert Systems, http://www.medicalalert-systems.com/ ... of some of the most popular medical alert devices ... announce that it is now offering special deals and ... are on a fixed income but would like to ... as very welcome news. , As a company spokesperson ...
Breaking Medicine News(10 mins):Health News:Pharmica Spends the Day Helping to Preserve Washington Crossing Historic Park 2Health News:New Helpline Provides Hope for Troubled Teens in Boca Raton 2Health News:WRNW1's KC Armstrong Expresses Thanks and Appreciation to Howard Stern 2Health News:AlignLife Springfield Office Donates 565 Canned Goods to Springfield Food Pantry 2Health News:Medical Alert Systems Website Now Offering Special Prices on the Popular Medical Guardian Product 2Health News:Medical Alert Systems Website Now Offering Special Prices on the Popular Medical Guardian Product 3
... As the medical community searches for better vaccines and ... believes he has discovered a new approach to boosting ... Ph.D., found that the same molecules used in drugs ... immune system, pushing them to make antibodies for protection ...
... Harold C. Simmons Comprehensive Cancer Center at UT Southwestern ... an elite distinction held by only the top-tier cancer ... first medical center in North Texas to attain this ... top cancer centers in recognition of innovative research and ...
... HealthDay Reporter , WEDNESDAY, Aug. 4 (HealthDay News) -- ... public health officials in California are urging residents, particularly ... infants, to make sure they,re immunized for the highly ... also higher than last year in Michigan, South Carolina, ...
... the Canadian Institutes for Health Research (CIHR) announced its ... on the list and two of them were headed ... Michael Cusimano will lead a team studying traumatic brain ... hospital,s director of trauma, will examine rural Canadians, access ...
... article in the current issue of Deutsches rzteblatt ... A. Lagrze examines whether or not childhood screening for ... disorders can occur even in very young children and ... the only eye disorder for which ophthalmological screening is ...
... Amanda Gardner HealthDay Reporter , TUESDAY, Aug. 3 ... go to an emergency room with a violent injury and ... episodes, new research finds. The authors calculated that for ... one violent episode in the future. The study was ...
Cached Medicine News:Health News:UR discovers new way to boost vaccines, seeks patent 2Health News:UT Southwestern's cancer center earns National Cancer Institute designation 2Health News:UT Southwestern's cancer center earns National Cancer Institute designation 3Health News:Spread of Whooping Cough Raises Concern 2Health News:Spread of Whooping Cough Raises Concern 3Health News:St. Michael's receives prestigious grants to study trauma 2Health News:One Therapy Session in ER Can Cut Teen Violence 2Health News:One Therapy Session in ER Can Cut Teen Violence 3
(Date:8/20/2014)... YORK , Aug. 20, 2014 ... is available in its catalogue: The ... http://www.reportlinker.com/p02051938/The-Market-for-Medical-Devices-in-EMEA .html The European, Middle Eastern ... of medical devices. As part of its coverage, ... EMEA concentrates on the EMEA medical device markets ...
(Date:8/20/2014)... Aug. 20, 2014 ... is available in its catalogue: EMR ... http://www.reportlinker.com/p0833392/EMR-2014-The-Market-for-Electronic-Medical-Records.html Kalorama ... medical records (EMR) for nearly a decade, and ... our findings. Our report has become the industry ...
(Date:8/19/2014)... NASHVILLE, Tenn. , Aug. 19, 2014 /PRNewswire/ ... to provide its patient experience technology to ... Health. Under the five-year agreement, CarePoint Health will ... of Bayonne Medical Center, Christ Hospital and Hoboken ... platform offers a range of software solutions to ...
Breaking Medicine Technology:The Market for Medical Devices in EMEA 2The Market for Medical Devices in EMEA 3The Market for Medical Devices in EMEA 4The Market for Medical Devices in EMEA 5EMR 2014: The Market for Electronic Medical Records 2EMR 2014: The Market for Electronic Medical Records 3EMR 2014: The Market for Electronic Medical Records 4EMR 2014: The Market for Electronic Medical Records 5EMR 2014: The Market for Electronic Medical Records 6EMR 2014: The Market for Electronic Medical Records 7EMR 2014: The Market for Electronic Medical Records 8Lincor Announces Agreement With CarePoint Health For State-Of-The-Art Patient Engagement Technology 2
... 12, 2012 Arriva Medical, a leading national ... has acquired Direct Diabetic Source, Inc. in a ... included a cash payment of $2.5 million at ... total $2.5 million.  Based in Sunrise, FL, Direct ...
... Ill. and SALT LAKE CITY, Jan. 12, 2012   ... supplies and equipment to school nurses, athletic trainers and ... EnableMart, a leading provider of assistive technology to the ... and arranged the transaction. In recent ...
Cached Medicine Technology:School Health Corporation Acquires EnableMart to Expand Product Offering Into Schools 2School Health Corporation Acquires EnableMart to Expand Product Offering Into Schools 3
... Autolet Impression is the advanced lancing device ... Owen Mumford. Autolet Impression features unique Comfort ... ultimate control and comfort when lancing. Comfort ... targeting the sensation and perception of pain. ...
... The Qwik-Let Elite has become ... sold models. This popularity is due ... features found in the design and ... this innovative device is priced for ...
... new Finnpipette Focus from Thermo Labsystems was ... performance. Advanced features such as the ... volume adjustment on microvolumes help to define ... channel pipettes. The new interchangeable handle plate ...
... Seven digital models cover the range from ... liquid fluently. Volume lock design prevents inadvertent ... the horizontal grip. Whole pipette is autoclavable ... ejector is all polypropylene. Suitable for one-handed ...
Medicine Products: