Navigation Links
Drug reduces risk of prostate cancer diagnosis in high-risk men
Date:3/31/2010

A drug already prescribed to shrink benign, enlarged prostates has been shown to reduce the risk of a prostate cancer diagnosis by 23 percent in men with an increased risk of the disease, a large international trial has found. Results are reported April 1 in the New England Journal of Medicine.

The four-year study found that dutasteride (Avodart) significantly reduced the chances that men would be diagnosed with the tumors that are most often treated excessively: those that fall in the mid-range of aggressiveness. These tumors, which account for the majority of all prostate cancers, grow unpredictably. This uncertainty leads many men to opt for surgery or radiation therapy treatments that can lead to incontinence and impotence.

"Dutasteride may potentially offer many thousands of men a way to reduce their risk of being diagnosed with prostate cancer," says the study's lead author Gerald Andriole, MD, chief of urologic surgery at Washington University School of Medicine in St. Louis. "This means more men could avoid unnecessary treatment for prostate cancer along with the costs and harmful side effects that can occur with treatment."

Andriole chaired the steering committee that oversaw the trial, known as REDUCE (Reduction by Dutasteride of Prostate Cancer Events), which was conducted at 250 sites in 42 countries. It is the first to evaluate chemoprevention for prostate cancer in men at increased risk of disease. The study was funded by GlaxoSmithKline, the manufacturer of Avodart.

The trial involved 8,231 men ages 50-75, who were randomly assigned to receive a placebo or a daily 0.5 mg dose of dutasteride, a drug that is known to shrink the prostate. Men in the study were considered to be at increased risk for prostate cancer because they had elevated PSA levels (2.5 ng/ml 10 ng/ml) but no evidence of cancer on biopsies performed within six months of enrolling in the trial.

"Many men every year are in the s
'/>"/>

Contact: Caroline Arbanas
arbanasc@wustl.edu
314-286-0109
Washington University School of Medicine
Source:Eurekalert

Page: 1 2 3 4 5

Related medicine news :

1. New Research Shows 'Kangaroo Mother Care' Reduces Newborn Deaths More than 50 Percent
2. Deep brain stimulation reduces epileptic seizures in patients with refractory partial and secondarily generalized seizures
3. New technique reduces tobacco smoke damage to lungs in mice
4. PSA Test Reduces Prostate Cancer Deaths by 40%
5. New drug candidate reduces blood lipids
6. Pioneering treatment reduces disability in premature babies with serious brain hemorrhage
7. Soccer reduces risk of falls and bone fractures
8. Drug dramatically reduces nausea and vomiting in bone marrow transplant patients
9. Targeted delivery of losartan reduces liver inflammation and scarring
10. Accelerated radiation therapy reduces toxicity in patients with advanced head and neck cancers
11. New cardiac CT technology drastically reduces patient radiation exposure
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/28/2015)... a bite of warm, gooey pepperoni pizza, and your ... stomach, ready to break down your meal. In many ... amok, triggering a burning sensation in the chest. Heartburn ... Americans have heartburn at least once a month. The ... can be stopped. , Heartburn or acid reflux symptoms ...
(Date:3/28/2015)... 28, 2015 India Network visitor ... made available to all visitors who purchase the plan ... members are encouraged to purchase the insurance program as ... of proper coverage for pre-existing medical conditions. Parents and ... two medical conditions with serious consequences to their health. ...
(Date:3/28/2015)... How best to treat and recover ... orthopaedic medicine. While diagnostic hip injections are commonly performed ... etiology, research presented today at the American Orthopaedic Society ... that pain relief from this diagnostic injection may not ... “Our study looked to assess if the amount of ...
(Date:3/28/2015)... 2015 Lately the student-athlete experience ... changes and proposals around the NCAA. In a March ... collegiate student-athletes across a spectrum of universities and sports ... challenges. The special panel consists of athletes who have ... from football, track and field, baseball, and volleyball. They ...
(Date:3/28/2015)... (PRWEB) March 28, 2015 ARDX will sponsor ... from 12pm -3pm at the Chesapeake Conference Center in Chesapeake, ... sponsoring an empowering event for women in the Hampton Roads ... the Stories of Women’s Lives. Women grow stronger through ... each other. This year the WWC™ theme is T-talk ...
Breaking Medicine News(10 mins):Health News:Bypass Your Heartburn Worries This Easter With Tylers Coffee 2Health News:India Network Health Insurance Today Announces New Eligibility Criteria for Pre-existing Condition Health Insurance Coverage for Visitors to the United States 2Health News:India Network Health Insurance Today Announces New Eligibility Criteria for Pre-existing Condition Health Insurance Coverage for Visitors to the United States 3Health News:Pain Injections for Hip Arthroscopy Patients May Not Predict Surgical Outcomes 2Health News:SCI TV Panel of Former College Athletes Discusses Student Athlete Experience 2Health News:SCI TV Panel of Former College Athletes Discusses Student Athlete Experience 3
... Post traumatic stress disorder is commonly thought to effect victims ... new University of Georgia study finds that it also can ... such as cancer. , The finding, scheduled to be published ... Social Work Practice, has major implications for helping children cope ...
... 2008, to be Proclaimed Light San Diego Pink Day, ... Komen for the Cure,the world,s largest grassroots network of ... forever, announced today that,its San Diego Affiliate will award ... help the uninsured and underinsured women and men in,San ...
... 8, 2008 Costs are rising on,everything from bread to ... every time a nurse visits a Medicaid patient in the ... assistance reimbursement,increase is clear, according to nurses and other home ... in the state,Capitol., The cost of a nurse,s visit ...
... Run Campaign to Support Jimmy Fund and ... Children,s Hospital Boston, ... home runs this baseball season will help support,children with medical needs ... Hess Corporation will donate $500 for every home run hit during ...
... Nonin Medical, Inc., in an,effort to ... use of remote,monitoring, unveiled the world,s first ... American Telemedicine Association (ATA) meeting,in Seattle, WA. ... pulse,oximeter is designed for interoperability, meeting the ...
... Experience on eBay, CHICAGO, April 8, 2008 ... the captain,s seat in the fight against cancer.,In ... is auctioning off a,behind-the-scenes tour and flight simulator ... Denver, Colo., including two domestic,roundtrip tickets to Denver ...
Cached Medicine News:Health News:Study: Treating post-traumatic stress first helps children overcome grief 2Health News:Study: Treating post-traumatic stress first helps children overcome grief 3Health News:Susan G. Komen for the Cure Awards San Diego Organizations Nearly $1 Million to Fight Breast Cancer 2Health News:Susan G. Komen for the Cure Awards San Diego Organizations Nearly $1 Million to Fight Breast Cancer 3Health News:Susan G. Komen for the Cure Awards San Diego Organizations Nearly $1 Million to Fight Breast Cancer 4Health News:Bayada Nurses Advocates for Increase in Medicaid Reimbursement Rate to Allow More Individuals to Receive Home Care and Hire More Skilled Staff 2Health News:Every Boston Red Sox Home Run Televised on NESN in 2008 to Help Children With Medical Needs 2Health News:Every Boston Red Sox Home Run Televised on NESN in 2008 to Help Children With Medical Needs 3Health News:Advancing Interoperability - Nonin(R) Medical Unveils World's First Bluetooth(R)-Enabled, Wireless Fingertip Pulse Oximeter 2Health News:Be in the Captain's Seat in the Fight Against Cancer 2Health News:Be in the Captain's Seat in the Fight Against Cancer 3
(Date:3/27/2015)... , March 27, 2015 Object recognition ... blind, visually impaired and elderly. The VelaSense ... individuals to lead more independent, productive and fulfilling lives. ... which will allow users to identify objects from a ... well as create customized object databases for personal use. ...
(Date:3/27/2015)... 27, 2015 Dynatronics Corporation (NASDAQ: DYNT ) ... appointed to the Company,s Board of Directors effective March 23, ... November 2014 of board member Joseph Barton .  ... our Board of Directors represents an important step forward for ... president of Dynatronics.  "Rich is a proven leader and is ...
(Date:3/27/2015)...  Holographic Optical Technologies of Augusta, Georgia ... imaging, is entering the world of consumer electronics with ... 20 th , 2015, the campaign will introduce the ... 22-inch displays will allow consumers to view fully three ... addition to the two displays, the company will also ...
Breaking Medicine Technology:VelaSense Object Recognition Technology for the Blind was unveiled at Baruch College's CCVIP 8th Annual Conference 2Dynatronics Announces Appointment of Richard J. Linder to Board of Directors 2Holographic Optical Technologies brings cutting-edge holograms to consumer market through upcoming Kickstarter campaign 2Holographic Optical Technologies brings cutting-edge holograms to consumer market through upcoming Kickstarter campaign 3
The Medtronic EOPA CAP® arterial cannula provides a simple solution to obtaining accurate arterial pressure readings....
Intermittent catheter...
Intermittent catheter...
... dimension in vitreoretinal surgery. ,By using ... purified perfluoro-n-octane, you can greatly expand ... for managing retinal detachments complicated by ... trauma. , ,Certified to be >99.9 ...
Medicine Products: