Navigation Links
Drug-induced liver injury is on the rise
Date:6/26/2013

Bethesda, MD (June 26, 2013) More people are being affected by drug-induced liver injury (DILI) than ever before, according to a new study in Gastroenterology, the official journal of the American Gastroenterological Association. This type of liver injury results from the use of certain prescription and over-the-counter medications, as well as dietary supplements, and is among the more challenging forms of liver disease due to its difficulty to predict, diagnose and manage.

Investigators conducted a population-based study in Iceland uncovering 19.1 cases of drug-induced liver injury per 100,000 inhabitants, per year. These results are significantly higher than the last population-based study of this kind, conducted in France from 1997-2000, which reported 13.9 cases per 100,000 inhabitants, per year.

The most commonly implicated drugs were amoxicillin-clavulante (penicillin used to fight bacteria), azathioprine (an immunosuppressive drug used in organ transplantation and autoimmune diseases) and infliximab (also used to treat autoimmune disease).

"Drug-induced liver injury is not a single, uncommon disease of the general population, but rather a series of rare diseases that occur only in persons who take specific medications," said Einar S. Bjrnsson, lead study author from the department of internal medicine, section of gastroenterology and hepatology, National University Hospital, Reykjavik, Iceland, and faculty of medicine at the University of Iceland. "Our study identified which medications put patients most at risk for developing liver diseases. With this information, physicians can better monitor and manage patients who are prescribed potentially liver-injuring drugs."

The study also showed that drug-induced liver injury was caused by a single prescription medication in 75 percent of cases, by dietary supplements in 16 percent and by multiple agents in 9 percent. Further, the incidence was similar in women and m
'/>"/>

Contact: Rachel Steigerwald
media@gastro.org
301-272-1603
American Gastroenterological Association
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Delivering the best care to the right patient at the right time
2. Dubai's Princess Haya Delivers Stirring Expo 2020 Speech in Paris
3. Author Delivers 25 Life-Building Tools for Recovering Addicts in New Book
4. Freedom Writers Foundation Founder, Erin Gruwell Delivers Keynote Address at American Career College Commencement Ceremony
5. Robert Oliver, Clearwater Professional, Explains Benefits of Medicaid Expansion
6. Novel Drug Delivery Systems Market (NDDS): Formulations (Oral & Injectable) Analysis in Research Report at RnRMarketResearch.com
7. Dr. Rod J. Rohrich Delivers Keynote Address on the Future of Rhinoplasty
8. New Drug Delivery Partnering Terms and Agreements Market Study Report Available at MarketResearchReports.Biz
9. Lauren Sciences independently recognized as a Technology Innovator in Drug Delivery with its V-Smart™ Platform, and selected as a Featured Company, in new report by MCD Group
10. ReNew Life Launches Daily Liver Support™—a Triple-Action, Daily Supplement for Optimal Liver Support
11. Novel Liver Stem Cell Model Could Speed Up Process for Developing New Drugs
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2015)... York, New York (PRWEB) , ... July 31, 2015 , ... ... to strut their stuff, Super-Sod debuted their new type of sod called Leisure ... registered trademark application in process. , To commemorate introduction of this new type of ...
(Date:7/31/2015)... ... July 31, 2015 , ... Recently touted by ... predictive health analytics , Jvion continues to disrupt the predictive analytic and ... that targets patient and population level illness to drive prevention and better health ...
(Date:7/31/2015)... ... July 31, 2015 , ... Jacksonville-based drug and ... True North Conference Center. The medical community, social workers, law enforcement, and government ... more aligned in the effort to better understand and combat sex trafficking. Lead ...
(Date:7/31/2015)... ... 2015 , ... According to the article published July 27 on My News LA, ... and extinguished by the city’s fire department before it caused major damage throughout the building. ... the fire, and it was a fire alarm system that tipped off fire fighters so ...
(Date:7/31/2015)... ... ... As part of their company mission, Dallas pet sitting company ... essential to the longevity of their business. It is for that reason they ... Sitters (NAPPS) annual Presents 4 Pets supply drive. Presents 4 Pets is ...
Breaking Medicine News(10 mins):Health News:Super-Sod Introduces Leisure Time(TM) Zoysia Grass with an Adirondack Chair Promotion 2Health News:Jvion Showcased as Leader in the Predictive Analytic Market 2Health News:Lakeview Health Links Sex Trafficking and Addiction in Special Jacksonville Educational Workshop 2Health News:Lakeview Health Links Sex Trafficking and Addiction in Special Jacksonville Educational Workshop 3Health News:Article on Recent Pasadena Courtroom Fire Highlights the Effectiveness of Fire Alarm Systems, Says Fire Protection Group Inc 2Health News:Article on Recent Pasadena Courtroom Fire Highlights the Effectiveness of Fire Alarm Systems, Says Fire Protection Group Inc 3Health News:Dallas-based Park Cities Pet Sitter Selects Non-Profit Animal Welfare Organization “Angie’s Friends” as this Year’s Recipient of their Presents 4 Pets Supply Drive. 2Health News:Dallas-based Park Cities Pet Sitter Selects Non-Profit Animal Welfare Organization “Angie’s Friends” as this Year’s Recipient of their Presents 4 Pets Supply Drive. 3Health News:Dallas-based Park Cities Pet Sitter Selects Non-Profit Animal Welfare Organization “Angie’s Friends” as this Year’s Recipient of their Presents 4 Pets Supply Drive. 4
... Researchers are questioning the opinion that dairy products provide ... a study conducted recently on collected information available that ... and consumption of dairy products show little or no ... to take about 800 to 1500mg of calcium for ...
... Researchers have found that the hormone estrogen is responsible for ... a boy to being a grown man. ,Laboratory ... hypothalamus is responsible of defeminization or removal of feminine traits ... the individual. This process seems to be the main neurological ...
... be evidence of insulin being produced in the brain that may ... evidence of insulin and related proteins being produced by the brain, ... ,The findings, which came out in the march, issue of the ... in pancreas, but in the brain as well. There had been ...
... out that the condition of preeclampsia that may cause ... mothers to their daughters.// ,Preeclampsia is a ... in the urine and swelling of hands and feet. ... cause severe complications to the pregnant mother and unborn ...
... effective treatment for patients having pain due osteoarthritis in one or ... full Lidoderm patch in the front of the knee and one ... result showed that after six weeks of treatment majority of the ... relief or more. To the other group the treatment was done ...
... COPD is a lung disease that often results from years ... test measuring // lung hyperinflation can be used to predict ... pulmonary disease (COPD) . ,For the study researchers compared ... to total lung capacity in 689 COPD patients. Results showed ...
Cached Medicine News:
(Date:7/30/2015)... 2015  Tandem Diabetes Care®, Inc. (NASDAQ: ... of the t:slim® and t:flex™ Insulin Pumps, today ... Agreements with Dexcom, Inc. to allow the integration ... Dexcom G5 and G6 continuous glucose monitoring ("CGM") ... platform with Dexcom,s future CGM systems is an ...
(Date:7/30/2015)... and VANCOUVER , July 30, 2015 ... today that it will report its second quarter 2015 ... will host a conference call and live webcast at ... financial results, clinical development programs and a general corporate ... on to the Investor Relations page of the OncoGenex ...
(Date:7/30/2015)... CHENGDU, China , July 30, 2015 ... "Company"), a pharmaceutical company that specializes in the patented ... active pharmaceutical ingredients (API), provided updates regarding the notice ... MKT LLC (the "Exchange") indicating that the Company was ... set forth in Sections 134 and 1101 of the ...
Breaking Medicine Technology:Tandem Diabetes Care Announces Development Agreement with Dexcom for Integration of Future Generation CGM Systems 2Tandem Diabetes Care Announces Development Agreement with Dexcom for Integration of Future Generation CGM Systems 3TPI Provides Update Regarding Non-Compliance with NYSE MKT Continued Listing Requirements 2
... NEW YORK, Feb. 4, 2011 WebMD Health Corp. (Nasdaq: ... and CEO, will deliver a presentation at the UBS 21st ... at 12:00 p.m. ET. Investors, analysts and the ... broadcast of the presentation over the Internet.  The broadcast can ...
... Aethlon Medical, Inc., (OTC Bulletin Board: AEMD ... Joyce has issued the following letter to shareholders. ... Shareholders: Contrary to the value reflected in our ... enterprise. We have created an expansive technology platform that provides ...
Cached Medicine Technology:Aethlon Medical Releases Shareholder Letter 2Aethlon Medical Releases Shareholder Letter 3Aethlon Medical Releases Shareholder Letter 4
The focus of HandEchart Professional is to offer a practical and basic electronic patient record keeping system that anyone can learn in minutes....
Archimedes is an innovative specialty calculator. Forget having to remember complicated formulas, just enter the values and out come the results....
A handy, quick reference for physicians, nurses, and other health care providers treating cancer patients....
A handy quick-reference tool for busy residents and clinicians with key facts and points essential for day-to-day patient care....
Medicine Products: