Navigation Links
Drug in new class of targeted therapies shows early promise against blood-related cancers
Date:5/19/2010

HACKENSACK, N.J. (May 19, 2010) A Phase I clinical trial of SNS-032, one of the first in a new class of drugs that inhibit cyclin-dependent kinases, demonstrated the drug's safety and potential clinical action against advanced chronic lymphocytic leukemia (CLL). Cyclin-dependent kinases are enzymatic proteins that are integrally involved in cellular metabolism, renewal and signaling, and are thought to play key roles in the growth of cancers. The drug did not demonstrate any clinical effect against advanced multiple myeloma, although researchers hope it might still prove to have some benefit against this blood cancer as part of combination therapy. The paper is published online in the Journal of Clinical Oncology.

"No drugs that target this cancer mechanism are on the market today," says study author David S. Siegel, M.D., Ph.D., Co-Chief, Multiple Myeloma, John Theurer Cancer Center at Hackensack University Medical Center. "I am hopeful that larger studies will show that this targeted therapy is useful against a number of advanced B cell malignancies."

Chronic lymphocytic leukemia (CLL) and multiple myeloma are both considered B cell malignancies, as they attack these cells, also known as B lymphocytes. B lymphocytes are white blood cells that develop in the bone marrow and make antibodies that protect the immune system. Both types of blood cancer leave their victims susceptible to infections and other serious complications. While there are treatments for both cancers, there is no cure, and more effective treatments are needed.

"At the John Theurer Cancer Center we are committed to exploring new treatment options for rare cancers, such as multiple myeloma and CLL," said Andrew L. Pecora, M.D., F.A.C.P., C.P.E., Chairman and Executive Administrative Director, John Theurer Cancer Center. "We will continue to research new therapies to help our patients live longer and to find a cure for these diseases."

Dr. Siegel
'/>"/>

Contact: Amy Leahing
amy.leahing@widmeyer.com
646-213-7245
John Theurer Cancer Center
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Retirement Community in Arizona Hosts Classic Car Show with Live Music
2. ‘Best in Class' Nursing Homes Recognized for Exemplary Customer, Workforce Satisfaction
3. Martin & Jones Announces Class Action Lawsuit Against Major Employer, Claims Thousands of Visiting Nurses Illegally Denied Overtime Pay
4. A medicine classic goes online and far afield
5. MetaGeek Announces Chanalyzer Pro Spectrum Analysis Software for Wi- Spy, Adds Device Classification, Device Finder and Automated Reports
6. Classic Maya history is embedded in commoners homes
7. New class of drug kills lymphoma cells
8. Exposure to 3 classes of common chemicals may affect female development
9. HealthLinkRx Announces Classes in Spanish for Occupational and Physical Therapists
10. Dr. Khanna to Attend the 13th annual Women in Film Malibu Golf Classic
11. Bad Habits Explain Class Differences in Health: Study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/4/2015)... , ... September 04, 2015 , ... Many consumers are looking for a quick and ... their solution. , The patent-pending K Med Cups provide a quick and simple way to ... relieve a cold, flu or cough. As a result, they enhance comfort and health. The ...
(Date:9/4/2015)... (PRWEB) , ... September 04, 2015 , ... Having access ... This has led to an increasing amount of unnecessary emergency room visits which affects ... and taxes the country’s health bill. Fortunately, a solution to alleviate this problem has ...
(Date:9/4/2015)... ... September 04, 2015 , ... Compliance ... to settlements under the Stark physician self-referral law. “Stark Law DOs and ... from Atlantic Information Services, Inc. (AIS), will detail which deals are attracting the ...
(Date:9/4/2015)... IL (PRWEB) , ... September 04, 2015 , ... Friday ... Geneva, IL hosting Generation Rescue’s A Night of Hope event supporting families affected by ... French and Rowena and Joe Salas, joined together at the Oscar Swan Inn to ...
(Date:9/3/2015)... ... September 03, 2015 , ... TransPack Toon gives users a set of ... wipes and framing transitions in 30 different styles. Presets range from snow, underwater, forest, ... X. , TransPack Toon features 90 cartoon transitions from 30 unique styles. Editors ...
Breaking Medicine News(10 mins):Health News:Redesigned Packaging for Powdered Medicinal Mix Invented by InventHelp® Client (CBA-2637) 2Health News:Telemedicine Platform DocChat Announces Launch Offering a Way for Patients to Consult Doctors and Receive Prescriptions 24/7 2Health News:Telemedicine Platform DocChat Announces Launch Offering a Way for Patients to Consult Doctors and Receive Prescriptions 24/7 3Health News:Sept. 17 Webinar to Offer Best Practices for Physician Contracts 2Health News:Jenny McCarthy & Donnie Wahlberg Help Raise Over $200,000 For Generation Rescue’s ‘Night Of Hope’ Chicago Charity Event 2Health News:Pixel Film Studios Releases TransPack Toon, a New FCPX Transition 2
... , A nano-sensor for better detection of Mad Cow ... advance in food safety, researchers in New York are ... low levels of the deadly prion proteins that cause ... sensor, which detects binding of prion proteins by detecting ...
... JOSE, Calif., March 3 Interwoven, Inc.,(Nasdaq: ... solutions, today,announced that it will present a joint ... the 2008 AIIM International Exposition and Conference,on March ... & Exhibition Center., (Logo: http://www.newscom.com/cgi-bin/prnh/20071205/INTWOVLOGO ), ...
... The Quigley,Corporation (Nasdaq: QGLY ) today reported net ... 31, 2007, compared to $14.2 million,reported for the same ... 2007,net sales were $39.5 million compared to $42.1 million ... quarter ended December 31, 2007 reflects a net sales,decrease ...
... to treat their diabetes ... and out, PRINCETON, N.J., March 3 Novo Nordisk, a,world ... program is back for a third year of providing free diabetes,education ... by,diabetes. This dynamic outreach kicks off in New York City, where ...
... Will Conduct, Webcast For Pet Owners, Covering ... March 3 Morris Animal Foundation (MAF) will,sponsor a ... their pets on,March 13, 2008, from 8:00 p.m. to ... all aspects of pain management, including common,causes of pain, ...
... Beauty Get a New Jolt with Java, ... destination that helps solve people,s everyday problems by,providing ... the,world,s most popular bean by providing interesting facts ... Awareness Month" in March.,HowToDoThings.com has created a Caffeine ...
Cached Medicine News:Health News:American Chemical Society's weekly PressPac -- Feb. 27, 2008 2Health News:American Chemical Society's weekly PressPac -- Feb. 27, 2008 3Health News:American Chemical Society's weekly PressPac -- Feb. 27, 2008 4Health News:American Chemical Society's weekly PressPac -- Feb. 27, 2008 5Health News:American Chemical Society's weekly PressPac -- Feb. 27, 2008 6Health News:American Chemical Society's weekly PressPac -- Feb. 27, 2008 7Health News:American Chemical Society's weekly PressPac -- Feb. 27, 2008 8Health News:American Chemical Society's weekly PressPac -- Feb. 27, 2008 9Health News:Blue Cross Blue Shield of Massachusetts and Interwoven to Present at 2008 AIIM International Exposition and Conference 2Health News:The Quigley Corporation Reports Fourth Quarter & 2007 Annual Results; Increases Investment to $6.5 million in Pharmaceutical R&D in 2007 2Health News:The Quigley Corporation Reports Fourth Quarter & 2007 Annual Results; Increases Investment to $6.5 million in Pharmaceutical R&D in 2007 3Health News:The Quigley Corporation Reports Fourth Quarter & 2007 Annual Results; Increases Investment to $6.5 million in Pharmaceutical R&D in 2007 4Health News:The Quigley Corporation Reports Fourth Quarter & 2007 Annual Results; Increases Investment to $6.5 million in Pharmaceutical R&D in 2007 5Health News:The Quigley Corporation Reports Fourth Quarter & 2007 Annual Results; Increases Investment to $6.5 million in Pharmaceutical R&D in 2007 6Health News:The Quigley Corporation Reports Fourth Quarter & 2007 Annual Results; Increases Investment to $6.5 million in Pharmaceutical R&D in 2007 7Health News:The Quigley Corporation Reports Fourth Quarter & 2007 Annual Results; Increases Investment to $6.5 million in Pharmaceutical R&D in 2007 8Health News:Video: DIVABETIC - Makeover Your Diabetes Kicks Off 2008 Events 2Health News:Video: DIVABETIC - Makeover Your Diabetes Kicks Off 2008 Events 3Health News:Video: DIVABETIC - Makeover Your Diabetes Kicks Off 2008 Events 4Health News:Pain Management For Your Pets, Key Information Every Pet Owner Should Know - Live Webcast to Pet Owners, March 13, 8:00 p.m. to 9:00 p.m. (EDT) Via Morris Animal Foundation 2Health News:HowToDoThings.com Brews Up New Uses for Coffee That Will Perk You Up in Recognition of March's 'Caffeine Awareness Month' 2
(Date:9/4/2015)... , Sept. 4, 2015  PTC Therapeutics, ... announce five recipients of its first-ever global awards ... Vision and Empowerment), designed to aid nonprofit organizations ... dystrophy (DMD) community. The announcement is made as ... World Duchenne Awareness Day on Monday, September 7, ...
(Date:9/4/2015)... , September 4, 2015 ... ), a clinical-stage pharmaceutical company focused on the development ... Company will participate in the upcoming Rodman & Renshaw ... September 8-10, 2015 in New York City ... Oramed, will present a corporate overview on September 9, ...
(Date:9/4/2015)... , September 4, 2015 Future ... Allergic Rhinitis drugs - new ... Where is the market for allergic rhinitis drugs ... Visiongain ,s new report shows you potential revenues ... prospects. Our 326 page report provides 273 ...
Breaking Medicine Technology:PTC Therapeutics Announces Five Winners In Its First-ever Global Duchenne Muscular Dystrophy Patient Group Award 2PTC Therapeutics Announces Five Winners In Its First-ever Global Duchenne Muscular Dystrophy Patient Group Award 3PTC Therapeutics Announces Five Winners In Its First-ever Global Duchenne Muscular Dystrophy Patient Group Award 4Oramed to Present at the Rodman & Renshaw Global Investment Conference 2Oramed to Present at the Rodman & Renshaw Global Investment Conference 3Allergic Rhinitis Drugs Market Forecast 2015-2025 2Allergic Rhinitis Drugs Market Forecast 2015-2025 3Allergic Rhinitis Drugs Market Forecast 2015-2025 4Allergic Rhinitis Drugs Market Forecast 2015-2025 5Allergic Rhinitis Drugs Market Forecast 2015-2025 6Allergic Rhinitis Drugs Market Forecast 2015-2025 7
... Globus Medical, Inc., the largest,privately held spinal ... in motion preservation technology, today announced the completion ... study. The,SECURE(R)-C device is designed to mimic the ... pain and restore function as an alternative to ...
... Siemens Healthcare and,Laboratory Corporation of America(R) Holdings ... non-exclusive agreement to discuss future,possibilities to co-develop ... of,companion diagnostics, metabolic syndrome, oncology and diabetes. ... developing new tests that,could make the biggest ...
Cached Medicine Technology:Globus Medical Completes Enrollment Of SECURE(R)-C Cervical Artificial Disc Clinical Trial 2Siemens and LabCorp Enter Agreement to Co-Develop New Clinical Diagnostic Tests 2Siemens and LabCorp Enter Agreement to Co-Develop New Clinical Diagnostic Tests 3Siemens and LabCorp Enter Agreement to Co-Develop New Clinical Diagnostic Tests 4
Each handle is designed to fit a specific trephine size. For use in performing free-hand uniform donor buttons....
Each handle is designed to fit a specific trephine size....
Each handle is designed to fit a specific trephine size....
Each handle is designed to fit a specific trephine size....
Medicine Products: