Navigation Links
Drug improves brain function in condition that leads to Alzheimer's
Date:7/20/2011

emory and conducted functional magnetic resonance imaging of their brains. These scans were used to map brain activity during performance of a memory task, allowing the researchers to compare each individual's status both on and off the drug. Compared to the normal participants, subjects with amnestic MCI who took the placebo had excess activity in the hippocampus, a part of the brain essential for memory. But when they had been taking levetiracetam for two weeks, the excess activity was reduced to the same level as that of the control subjects; memory performance in the task they performed also was improved to the level of the controls.

The findings have possible implications for the progression to Alzheimer's disease. Studies showing excess activity in the hippocampus in patients with aMCI have found that if these patients are followed for a number of years, those with the greatest excess activation have the greatest further drop in memory and are more likely to receive a diagnosis of Alzheimer's over the next four to six years.

Other recent research provides a clue as to why this might be the case, says Gallagher, the Krieger-Eisenhower Professor of Psychological and Brain Sciences in Johns Hopkins' Krieger School of Arts and Sciences.

"Because some of the physiology that creates Alzheimer's disease in the brain is driven by greater brain activity, this excess activity might be like having your foot on the accelerator if you are on the path to Alzheimer's," Gallagher said. "So the next step in this line of research will be to test that idea to see whether reducing excess activity might actually slow progression to Alzheimer's for patients with aMCI."

Between 8 and 15 percent of patients with aMCI progress to an Alzheimer's diagnosis every year, making aMCI a stage of transition between normal aging and neurodegenerative disease. At present there is no effective treatment to modify this progression before irreversible damage ha
'/>"/>

Contact: Lisa DeNike
Lde@jhu.edu
443-287-9960
Johns Hopkins University
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. For Some Prostate Cancer Patients, Combo Treatment Improves Survival
2. Arthroscopic treatment of common hip problem improves range of motion
3. Medicaid Coverage Substantially Improves Access to Care: Study
4. Endosonography followed by surgical staging improves quality of life, according to ASTER study
5. Medicaid increases use of health care, decreases financial strain, improves health
6. PACS improves radiologists use of clinical decision support systems
7. Extended sleep improves the athletic performance of collegiate basketball players
8. CT angiography improves detection of heart disease in African-Americans
9. Life Expectancy Improves for Type 1 Diabetics
10. Innovative duct tape strategy saves hospitals time, money; improves infection prevention
11. Study shows pine bark naturally improves heart function
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/28/2015)... March 01, 2015 Heart diseases are ... 10 percent of urban adult population and 5 percent ... heart diseases and 20-30 percent of them require specialized ... ailments and coronary vascular diseases (CVD). , A division ... new market research report titled “Indian Coronary Stent Market ...
(Date:2/28/2015)... 28, 2015 The Classic Denture ... a new special. Throughout all of March patients ... , This service can help overall mouth ... pain. Patients may notice certain symptoms that suggest the ... These symptoms include: , 1.    Pain, clicking, and popping in ...
(Date:2/28/2015)... 28, 2015 A study out of ... gene therapy procedure for the treatment of a hereditary ... Authored by Dr. Robert MacLaren, professor of ... the Lancet Medical Journal on January 16, 2014 , ... rare genetic disorder that mostly affects men and leads ...
(Date:2/28/2015)... Beach, CA (PRWEB) February 28, 2015 ... needs of Central Coast area residents, recently announced a ... System. It’s a treatment option for new and ... kick off 2015 with a bright, white smile, Dr. ... discounted price of $299, marked down from the regular ...
(Date:2/28/2015)... 28, 2015 On Thursday, February 26th, Forbes ... Easy For Scammers To Steal Your Data , which stresses ... hands on a DIY phishing kit, or any kind of ... on another important point about how everyone’s cyber security is ... implemented, “like compromising legitimate content management systems or blogs in ...
Breaking Medicine News(10 mins):Health News:India Coronary Stent Market 2019 Forecasts Analysis in New Research Report Available at MarketReportsOnline.com 2Health News:India Coronary Stent Market 2019 Forecasts Analysis in New Research Report Available at MarketReportsOnline.com 3Health News:Classic Denture Center in Portland Oregon is Offering March Discount 2Health News:New Gene Therapy Procedure Could Hold Key to Preventing Blindness for Certain Patients 2Health News:Pismo Beach Dentist Announces Special for Zoom! Teeth Whitening 2Health News:DIY Phishing and Malware Kits Make it Easy to Compromise Businesses in More Ways than One 2Health News:DIY Phishing and Malware Kits Make it Easy to Compromise Businesses in More Ways than One 3Health News:DIY Phishing and Malware Kits Make it Easy to Compromise Businesses in More Ways than One 4
... and more complications later, studies find , , MONDAY, Oct. ... arthritis face twice the risk of a heart attack, ... to have more heart-related complications, new research says. ... which causes the lower chambers of the heart to ...
... written and verbal instructions on the proper way to ... to suffer the serious gastrointestinal and brain bleeding problems ... to new research from the University of Pennsylvania School ... Journal of General Internal Medicine , also shows ...
... Mo. The blood circulates through the body ... beginning to understand. Now, University of Missouri researcher ... and Blood Institute,s prestigious Method to Extend Research ... defining the signaling processes that control blood flow ...
... SpectraCell Laboratories, Inc.,announced that it has doubled ... a 20,000 sq. ft. building that was ... expansion added a second freestanding 20,000 sq.,ft. ... $3.5 million facility houses,SpectraCell,s state-of-the-art clinical laboratory ...
... offer ,Stem Cells 102, to present facts to ... issues surrounding the,safety and benefits of stem cell ... University of,Michigan experts are providing educational information to ... federal and state,oversight that apply to all human ...
... 27 The HealthCentral,Network, Inc. (http://www.HealthCentral.com ) ... business development for HealthCentral, has been,named President and ... a proven track record of growing young businesses, ... be responsible for,audience growth, user engagement, and revenue, ...
Cached Medicine News:Health News:Rheumatoid Arthritis a Threat to the Heart 2Health News:Rheumatoid Arthritis a Threat to the Heart 3Health News:Rheumatoid Arthritis a Threat to the Heart 4Health News:Better instructions reduce complications among patients using common blood thinner 2Health News:Better instructions reduce complications among patients using common blood thinner 3Health News:Researcher to provide new insight for treating vascular disease 2Health News:SpectraCell Laboratories Expands Operations in New Facility 2Health News:The Truth About Stem Cell Science 2Health News:The Truth About Stem Cell Science 3Health News:The Truth About Stem Cell Science 4Health News:The HealthCentral Network Names Jeremy Shane President and Chief Operating Officer 2Health News:The HealthCentral Network Names Jeremy Shane President and Chief Operating Officer 3
(Date:2/27/2015)... 27, 2015  Two mass spectrometry technologies ... as their effectiveness is established, according to ... Information says that while mass spectrometry (mass ... tool in proteomic biomarker discovery and validation, ... traditional techniques has struggled to elucidate molecular ...
(Date:2/26/2015)... RnRMarketResearch.com adds Corneal Ulcers ... to its store. This report p provides an ... The report "Corneal Ulcers - Pipeline Review, H2 2014" ... Corneal Ulcers. Corneal Ulcers are primarily result of ... infections & fungal infections. The symptoms of the ...
(Date:2/26/2015)... , Feb. 26, 2015  AbbVie (NYSE: ... abstracts of studies in its neuroscience and oncology ... the 67 th American Academy of Neurology ... , from April 18-25. The accepted abstracts feature ... in addition to investigational treatments in AbbVie,s pipeline. ...
Breaking Medicine Technology:Report: "Softer" Mass Spec Techniques Gaining Popularity in Biomarker Discovery 2Report: "Softer" Mass Spec Techniques Gaining Popularity in Biomarker Discovery 3Corneal Ulcers Therapeutics Companies and Drugs Pipeline H2 2014 Review Research Report 2Corneal Ulcers Therapeutics Companies and Drugs Pipeline H2 2014 Review Research Report 3Corneal Ulcers Therapeutics Companies and Drugs Pipeline H2 2014 Review Research Report 4Corneal Ulcers Therapeutics Companies and Drugs Pipeline H2 2014 Review Research Report 5AbbVie's Ongoing Research in Neuroscience and Oncology will be Featured at the 2015 American Academy of Neurology Annual Meeting 2AbbVie's Ongoing Research in Neuroscience and Oncology will be Featured at the 2015 American Academy of Neurology Annual Meeting 3AbbVie's Ongoing Research in Neuroscience and Oncology will be Featured at the 2015 American Academy of Neurology Annual Meeting 4AbbVie's Ongoing Research in Neuroscience and Oncology will be Featured at the 2015 American Academy of Neurology Annual Meeting 5AbbVie's Ongoing Research in Neuroscience and Oncology will be Featured at the 2015 American Academy of Neurology Annual Meeting 6AbbVie's Ongoing Research in Neuroscience and Oncology will be Featured at the 2015 American Academy of Neurology Annual Meeting 7
... Utah, May 3, 2011 Healthcare workers now have the ... take precautions to better protect themselves, and share information and ... BD Medical, a segment of BD (Becton, Dickinson and Company) ... The BD Making Safety Safer(SM) program will provide nurses ...
... GenVec, Inc. (Nasdaq: GNVCD) announced that it will release financial ... Monday, May 9, 2011 after market close.  GenVec will hold ... 10, 2011 to discuss the company,s first quarter financial results ... live conference call, please dial 877-558-0567 (U.S. or Canada) or ...
Cached Medicine Technology:Resource Now Available to Help Clinicians Reduce Risk of Blood Exposure from Short Peripheral IV Catheter Insertion 2Resource Now Available to Help Clinicians Reduce Risk of Blood Exposure from Short Peripheral IV Catheter Insertion 3GenVec to Host First Quarter 2011 Earnings Call and Webcast 2
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: