Navigation Links
Drug for advanced kidney cancer shrinks tumors prior to surgery
Date:2/17/2010

Chapel Hill, N.C. - More than 57,000 Americans face a diagnosis of kidney cancer each year. Now patients with advanced disease may soon have another treatment option. Physicians who conducted a pilot study at UNC Lineberger Comprehensive Cancer Center found that therapy before surgery with the drug sorafenib can reduce the size of large tumors and could be safely undertaken administered without adding significantly to the risks of surgery.

Their results are published in the Feb. 16, 2010 online issue of the Journal of Clinical Oncology.

Kimryn Rathmell, MD, PhD, a UNC Lineberger physician-scientist, is the study's principal investigator. "We found that primary kidney tumors responded to this therapy, shrinking up to 40 percent prior to surgery. What this means for kidney cancer patients is that their surgery may be less extensive and, we hope, can provide a better outcome for patients because of tumor shrinkage," she says. Rathmell is an assistant professor of medicine at UNC-Chapel Hill.

At present, removal of the primary tumor (often with the kidney as well) is the standard treatment for patients with kidney cancer, whether the disease is localized to the kidney or has spread to distant sites. This broad spectrum includes patients with very large tumors that may not be ideal for surgical removal as well as patients who may benefit from early systemic interventions, but who would also benefit from removing the kidney later. This study addressed the question of whether systemic therapy, and in particular, therapy that targets the process by which tumors seek and find new blood vessels to fuel their growth, can benefit patients before they undergo surgery to remove tumors.

The study was conducted to evaluate the safety and feasibility of preoperative treatment using sorafenib (Nexavar) in 30 patients with stage two or higher kidney cancer including metastatic disease. Patients received their treatment at UNC Lineberger
'/>"/>

Contact: Ellen de Graffenreid
edegraff@med.unc.edu
919-962-3405
University of North Carolina School of Medicine
Source:Eurekalert

0

GOOD

Page: 1 2 3

Related medicine news :

1. Split-course palliative radiotherapy confirmed as effective treatment for advanced NSCLC
2. UH Case Medical Center researchers publish promising findings for advanced cervical cancer
3. Racial disparities persist in the diagnosis of advanced breast cancer and colon cancer in the U.S.
4. New Drug Slows Advanced Kidney Cancer
5. Nutricap Labs Energizes 2010 with Move to More Advanced GMP Certified Facility
6. Advanced Foot and Ankle Specialists Improves Efficiency, Workflow With Aprima Electronic Health Record
7. UCLA study shows metformin is safe for patients with advanced heart failure and diabetes mellitus
8. Entest BioMedical Enters into LOI with Advanced Light Devices to Develop Laser Platform for Stem Cell / Laser COPD Treatment
9. TouchSurfaces.Org Launches Public Health Information Site for Advanced Disinfectant Solutions for Use Around Children and Pets
10. Study shows modest improvement in advanced lung cancer overall survival rates
11. Advanced Health Media Honored at NJ Finest Award Ceremony
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/25/2013)... (HealthDay News) -- Many viruses and parasites that affect ... -- a bacteria-borne illness than can result in liver ... parks, according to a veterinarian. These germs ... the air, said Dr. Susan Nelson, a clinical associate ... of these serious diseases can be fatal, even with ...
(Date:5/25/2013)... (PRWEB) May 25, 2013 Providing patients with ... Diet Doc team of weight management professionals. But, aside from ... and effectively, Diet Doc’s hCG diets also provide ... abuse during childhood like bullying, more control over their lives ... of dealing with the underlying factors of weight gain derived ...
(Date:5/25/2013)... New York,NY (PRWEB) May 25, 2013 ... SizeItUp officially declared the integration of the 2012 ... Lamborghini Aventador is the latest entrant in the list ... Designed intelligently, the vehicle is all set to thrill ... with vicious acceleration power and spectacular looks, the 2012 ...
(Date:5/25/2013)... (PRWEB) May 25, 2013 According to ... most beautiful and powerful women that ever lived. Cleopatra’s ... by some of the most powerful men in her ... beauty remedies to keep her skin glowing and fresh, ... with bees- wax, maringa oil and cyprus grass. , ...
(Date:5/25/2013)... 2013 For college students, few ... Increasingly, they are turning to prescription stimulants like ... For more on this, go to http://www.sciencedaily.com/releases/2013/05/130501145151.htm ... warns that students who pick up Adderall, “just ... for developing a physical and psychological dependency. While ...
Breaking Medicine News(10 mins):Health News:Hidden Dangers Dog Dog Parks 2Health News:hCGTreatments / Diet Doc hCG Diets & Weight Loss Plans Announces hCG Diet Plans for Those Suffering from Abuse-Related Weight Gain 2Health News:hCGTreatments / Diet Doc hCG Diets & Weight Loss Plans Announces hCG Diet Plans for Those Suffering from Abuse-Related Weight Gain 3Health News:Rim Fitments Provider SizeItUp Launches The Database Integration For The 2012 Lamborghini Aventador 2Health News:The Cleopatra Lift - A New Non Surgical Option to Aging Offered by Vancouver Physician 2Health News:The Cleopatra Lift - A New Non Surgical Option to Aging Offered by Vancouver Physician 3Health News:Addiction and Drug Abuse: Study Drug Adderall Abuse Spikes During Finals 2
... ... a secret to ,alcohol rehab success, and can it be measured? , ... London, UK (PRWEB) November 21, 2009 -- Linwood ... enough alcohol to create a risk of developing alcohol-related liver disease*, it is hardly a ...
... PRINCETON, NJ, Nov. 20 /PRNewswire-FirstCall/ - NUCRYST Pharmaceuticals Corp. announced ... on Monday, December 21, 2009. The purpose of the Meeting ... special resolution is to approve and authorize the sale of ... on the terms provided for in the asset purchase agreement ...
... , WASHINGTON, Nov. 20 ... Senate to make essential changes its health reform bill in ... and conscience protection on abortion, protect access to health care ... The bishops called the Senate health care bill an "enormous ...
... ... their Health Care Vote , ... Washington, DC (Vocus) November 20, 2009 -- Senators and congressmen running for re-election next year ... voting for House Speaker Nancy Pelosi’s health care bill, according to a breaking Zogby International/ ...
... , CHICAGO, Nov. 20 The American Dental Association ... (FDA) to establish appropriate classifications for tooth-whitening chemicals. ... that are often administered without the benefit of professional ... that the application of chemically based tooth whitening or ...
... HAIFA, Israel, November 20 Cardio ... of advanced cardiovascular surgery technology, today announced that,the company,s ... Europe, Canada and the Far East for its proprietary ... Cardio Vascular Medical Device already ...
Cached Medicine News:Health News:Linwood Group Reveal How to Decide whether Alcohol Rehab Centres are a Success or Not 2Health News:Linwood Group Reveal How to Decide whether Alcohol Rehab Centres are a Success or Not 3Health News:Linwood Group Reveal How to Decide whether Alcohol Rehab Centres are a Success or Not 4Health News:NUCRYST Announces Special Meeting of Shareholders 2Health News:NUCRYST Announces Special Meeting of Shareholders 3Health News:U.S. Bishops Voice Disappointment in Abortion-Funding Provisions in Senate Health Bill, Urge Better Care for Immigrants and Affordability 2Health News:Just 25% of Voters in Competitive 2010 Senate Races “Much More Likely” to Support Pelosi-Democrats Who Voted for Health Care Bill 2Health News:Just 25% of Voters in Competitive 2010 Senate Races “Much More Likely” to Support Pelosi-Democrats Who Voted for Health Care Bill 3Health News:American Dental Association Petitions FDA to Classify, Regulate Tooth-Whitening Products 2Health News:Cardio Vascular Medical Device to Apply for Additional Patents in Europe, Canada and Far East 2
(Date:5/23/2013)... Calif. , May 23, 2013 More ... cancer may not benefit from chemotherapy and still have ... the launch of one of the largest sources of ... new website and interactive Facebook page provide recently diagnosed ... they can safely avoid chemotherapy. "We anticipate ...
(Date:5/23/2013)... , May 23, 2013  Every day, their baby stopped ... to his lungs. April and Bryan Gionfriddo ... weren,t true. "Quite a few doctors said he ... says April Gionfriddo , about her now ... that would work, we would take it and run with ...
(Date:5/23/2013)...  Spring Bank Pharmaceuticals, Inc., a biopharmaceutical company developing ... announced that it has initiated dosing in a Phase ... oral therapy for the treatment of HCV infection. This study ... designed to assess both the safety and antiviral efficacy ... for the treatment of chronic HCV infections and is ...
Breaking Medicine Technology:Agendia Launches Social Media Campaigns to Help Breast Cancer Patients with Chemotherapy Decisions 2Agendia Launches Social Media Campaigns to Help Breast Cancer Patients with Chemotherapy Decisions 3Baby's life saved with groundbreaking 3D printed device from U-M that restored his breathing 2Baby's life saved with groundbreaking 3D printed device from U-M that restored his breathing 3Baby's life saved with groundbreaking 3D printed device from U-M that restored his breathing 4Spring Bank Pharmaceuticals Initiates a Phase I Clinical Trial for SB 9200 in HCV-infected Patients 2Spring Bank Pharmaceuticals Initiates a Phase I Clinical Trial for SB 9200 in HCV-infected Patients 3
... that a new market research report is available ... Invasive Surgery Market.(2010 - 2015) ... Surgery Market (2008 – 2015) The ... (MIS) has brought about significant changes in the ...
... (Nasdaq: ELGX ), developer of minimally ... publication of results from its pivotal, multicenter, prospective ... endovascular repair of abdominal aortic aneurysm (AAA) using ... extension. The trial demonstrated 100% ...
Cached Medicine Technology:Reportlinker Adds Global Minimally Invasive Surgery Market.(2010 - 2015) 2Reportlinker Adds Global Minimally Invasive Surgery Market.(2010 - 2015) 3Reportlinker Adds Global Minimally Invasive Surgery Market.(2010 - 2015) 4Reportlinker Adds Global Minimally Invasive Surgery Market.(2010 - 2015) 5Reportlinker Adds Global Minimally Invasive Surgery Market.(2010 - 2015) 6Reportlinker Adds Global Minimally Invasive Surgery Market.(2010 - 2015) 7Reportlinker Adds Global Minimally Invasive Surgery Market.(2010 - 2015) 8Reportlinker Adds Global Minimally Invasive Surgery Market.(2010 - 2015) 9Reportlinker Adds Global Minimally Invasive Surgery Market.(2010 - 2015) 10Reportlinker Adds Global Minimally Invasive Surgery Market.(2010 - 2015) 11Endologix Announces Publication of Clinical Trial Results Supporting Anatomical Fixation with a Suprarenal Aortic Extension 2Endologix Announces Publication of Clinical Trial Results Supporting Anatomical Fixation with a Suprarenal Aortic Extension 3
Select Support Brief...
Provides upper and lower arm support. Extends to the lower arm and across the shoulders. Has two columns of hook & eye closure for added adjustability....
... from medium compression weight ... provides upper back compression ... the arms. Arm length ... Wonderfabric™ unraveling. Velcro® closing ...
Sub Pectoral Bra...
Medicine Products: