Navigation Links
Drug for advanced kidney cancer shrinks tumors prior to surgery
Date:2/17/2010

Chapel Hill, N.C. - More than 57,000 Americans face a diagnosis of kidney cancer each year. Now patients with advanced disease may soon have another treatment option. Physicians who conducted a pilot study at UNC Lineberger Comprehensive Cancer Center found that therapy before surgery with the drug sorafenib can reduce the size of large tumors and could be safely undertaken administered without adding significantly to the risks of surgery.

Their results are published in the Feb. 16, 2010 online issue of the Journal of Clinical Oncology.

Kimryn Rathmell, MD, PhD, a UNC Lineberger physician-scientist, is the study's principal investigator. "We found that primary kidney tumors responded to this therapy, shrinking up to 40 percent prior to surgery. What this means for kidney cancer patients is that their surgery may be less extensive and, we hope, can provide a better outcome for patients because of tumor shrinkage," she says. Rathmell is an assistant professor of medicine at UNC-Chapel Hill.

At present, removal of the primary tumor (often with the kidney as well) is the standard treatment for patients with kidney cancer, whether the disease is localized to the kidney or has spread to distant sites. This broad spectrum includes patients with very large tumors that may not be ideal for surgical removal as well as patients who may benefit from early systemic interventions, but who would also benefit from removing the kidney later. This study addressed the question of whether systemic therapy, and in particular, therapy that targets the process by which tumors seek and find new blood vessels to fuel their growth, can benefit patients before they undergo surgery to remove tumors.

The study was conducted to evaluate the safety and feasibility of preoperative treatment using sorafenib (Nexavar) in 30 patients with stage two or higher kidney cancer including metastatic disease. Patients received their treatment at UNC Lineberger
'/>"/>

Contact: Ellen de Graffenreid
edegraff@med.unc.edu
919-962-3405
University of North Carolina School of Medicine
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Split-course palliative radiotherapy confirmed as effective treatment for advanced NSCLC
2. UH Case Medical Center researchers publish promising findings for advanced cervical cancer
3. Racial disparities persist in the diagnosis of advanced breast cancer and colon cancer in the U.S.
4. New Drug Slows Advanced Kidney Cancer
5. Nutricap Labs Energizes 2010 with Move to More Advanced GMP Certified Facility
6. Advanced Foot and Ankle Specialists Improves Efficiency, Workflow With Aprima Electronic Health Record
7. UCLA study shows metformin is safe for patients with advanced heart failure and diabetes mellitus
8. Entest BioMedical Enters into LOI with Advanced Light Devices to Develop Laser Platform for Stem Cell / Laser COPD Treatment
9. TouchSurfaces.Org Launches Public Health Information Site for Advanced Disinfectant Solutions for Use Around Children and Pets
10. Study shows modest improvement in advanced lung cancer overall survival rates
11. Advanced Health Media Honored at NJ Finest Award Ceremony
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/30/2015)... ... June 30, 2015 , ... Bill Howe Plumbing, ... in San Diego. Bill Howe offers all employees ample opportunity for education and ... most notably through the local Plumbing-Heating-Cooling-Contractors of San Diego (PHCC-SD). The San Diego ...
(Date:6/30/2015)... ... , ... Some may define success as the sum of small efforts repeated ... Athletic Trainers’ Association (NYSATA) and its members continue to be acknowledged and applauded by ... number of members also received honors at the national level. , For ...
(Date:6/30/2015)... ... June 30, 2015 , ... The American Psychiatric ... at Disney’s Coronado Springs Resort in Lake Buena Vista, Florida, and will offer ... premiere event for psychiatric-mental health nursing draws more than 1,500 health care professionals ...
(Date:6/30/2015)... ... June 30, 2015 , ... Medflow, the leader in the ... health records system from the company exclusively dedicated to helping eye care professionals ... intuitive state-of-the-art solution combining modern cloud technology with Medflow’s proven expertise in the ...
(Date:6/30/2015)... ... ... Purdy, the spokesperson for Dephinitive Systems LLC, announces today that the company will officially ... eXtra Operability (XO) which was chosen to reflect the company’s commitment to health care ... XO, based in Cleveland OH, is part of the Cadrillion Capital family of Healthcare ...
Breaking Medicine News(10 mins):Health News:Two Local San Diego Plumbers from Bill Howe Plumbing, Inc. Graduate from PHCC Academy 2Health News:Two Local San Diego Plumbers from Bill Howe Plumbing, Inc. Graduate from PHCC Academy 3Health News:NYSATA and Members Recognized with National Awards 2Health News:NYSATA and Members Recognized with National Awards 3Health News:American Psychiatric Nurses Association 29th Annual Conference: Continuing Education and Collaboration in Psychiatric-Mental Health and Nursing 2Health News:American Psychiatric Nurses Association 29th Annual Conference: Continuing Education and Collaboration in Psychiatric-Mental Health and Nursing 3Health News:Medflow Launches MEDFLOW 2.0 EHR – The Cloud-Based Ophthalmology EHR 2Health News:Dephinitive Systems Is Getting a New Name 2
... Still Feel Targeted By Tobacco Advertising and Find It,Easy ... across Kansas will,rally against tobacco on April 2 as ... annual Kick Butts Day, sponsored by the Campaign,for Tobacco-Free ... a list of local events, go to http://www.kickbuttsday.org/events ...
... Still Feel Targeted By Tobacco Advertising & Find It,Easy ... across Florida,will rally against tobacco on April 2 as ... annual Kick Butts Day, sponsored by the,Campaign for Tobacco-Free ... a list of local events, go to, http://www.kickbuttsday.org/events )., ...
... 27 Marshall Erdman &,Associates (Erdman) was ... Healthcare,s" 2008 Construction & Design Survey. The ... industry; it,examines year-over-year sales, contracted square footage ... and number of architects, engineers,and interior designers., ...
... knowledge and building important international relationships is top ... DendriMed Research Director Dr Raisa Monteiro, when she ... in May. , One of two Australian life ... candidates for the prestigious 2008 Advancing BioBusiness Award, ...
... alliances that,lead to increased sales and are mutually ... selection of compatible partners. Companies,that succeed in alliance ... articulating the rationale behind the effort, and then,choosing ... Practices, LLC,s white paper "Generating Value From Strategic,Alliances ...
... Practice Information Management Software Introduces Comprehensive Patient and Information Tracking ... ... Back-Up, DALLAS, March 27 Eklin Medical Systems, a ... Practice Management software for veterinary care,(VIA(R)), is showcasing VIA,s new Hospital ...
Cached Medicine News:Health News:Kansas Kids 'Kick Butts' on April 2 2Health News:Kansas Kids 'Kick Butts' on April 2 3Health News:Florida Kids 'Kick Butts' on April 2 2Health News:Florida Kids 'Kick Butts' on April 2 3Health News:Florida Kids 'Kick Butts' on April 2 4Health News:'Modern Healthcare' Names Marshall Erdman Nation's Top Design-Build Company 2Health News:DendriMed scientist seeks to fast-track success 2Health News:Eklin VIA(R) Showcases Hospitalization Functionality to Veterinary Care Market 2Health News:Eklin VIA(R) Showcases Hospitalization Functionality to Veterinary Care Market 3
(Date:6/30/2015)... , June 30, 2015  Today, the National Mobility ... the 2015 National Mobility Awareness Month Local Heroes Contest ... Hero online entries that received 1.3 million votes. The ... , Toyota Mobility , and Valley Honda ... and Vantage Mobility International (VMI) and ...
(Date:6/30/2015)... 2015  Avanir Pharmaceuticals, Inc. today announced top-line ... treatment with NUEDEXTA ® was associated with ... affect (PBA) in patients with traumatic brain injury ... characterized by sudden and uncontrollable outbursts of laughing ... brain injury. PRISM II is a phase IV ...
(Date:6/30/2015)... June 30, 2015  EnteroMedics Inc. (NASDAQ: ETRM ... neuroblocking technology to treat obesity, metabolic diseases, and other ... public offering  of 40,229,886 units. Each unit consists of ... A warrant to purchase one share of common stock, ... one share of common stock, at a purchase price ...
Breaking Medicine Technology:NMEDA Announces National Contest Winners 2NMEDA Announces National Contest Winners 3Avanir Pharmaceuticals Announces Positive Top-line Results from Stroke and TBI Cohorts of PRISM II Study 2Avanir Pharmaceuticals Announces Positive Top-line Results from Stroke and TBI Cohorts of PRISM II Study 3Avanir Pharmaceuticals Announces Positive Top-line Results from Stroke and TBI Cohorts of PRISM II Study 4Avanir Pharmaceuticals Announces Positive Top-line Results from Stroke and TBI Cohorts of PRISM II Study 5Avanir Pharmaceuticals Announces Positive Top-line Results from Stroke and TBI Cohorts of PRISM II Study 6Avanir Pharmaceuticals Announces Positive Top-line Results from Stroke and TBI Cohorts of PRISM II Study 7EnteroMedics Inc. Announces Pricing of $35.0 Million Public Offering of Common Stock and Warrants 2EnteroMedics Inc. Announces Pricing of $35.0 Million Public Offering of Common Stock and Warrants 3
... BROOMFIELD, Colo., April 12, 2011 Lanx ® , ... developing and commercializing innovative devices for spinal surgery, today ... (Concero) at the 2011 American Association of Neurological Surgeons ... Concero system is a minimally invasive fixation alternative to ...
... Living Cell Technologies Limited (ASX: LCT; OTCQX: LVCLY), ... implant therapy to treat diabetes, today announced that it ... through a placement of shares to Otsuka Pharmaceutical Factory, ... Otsuka group of companies. For the placement, Otsuka will ...
Cached Medicine Technology:Lanx®, Inc. Announces Launch of Concero™ Facet Screw System for Spinal Fusion 2LCT and Otsuka of Japan Share Common DIABECELL(R) Vision 2LCT and Otsuka of Japan Share Common DIABECELL(R) Vision 3LCT and Otsuka of Japan Share Common DIABECELL(R) Vision 4LCT and Otsuka of Japan Share Common DIABECELL(R) Vision 5
The Excel Series from DGH-KOI is an excellent choice for the ophthalmic surgeon performing cataract and other general ophthalmic procedures. With a broad range of blade options and our special Excel ...
New! Visually superior, micrometer handle, single foot plate, blade extends to 3.0 mm....
The new TRC-NW200 Non-Mydriatic Retinal Camera combines Topcons years of experience in retinal imaging with the latest advances in digital and electronic technology....
... ClosureWire Vascular Closure System (VCS) utilizes ... Compression., ,The Boomerang ClosureWire technique creates ... of the arteriotomy and just outside ... targeted internal compression of both the ...
Medicine Products: